Zobrazeno 1 - 10
of 76
pro vyhledávání: '"R Bryan Sutton"'
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270188 (2022)
Ferlins are complex, multi-domain proteins, involved in membrane trafficking, membrane repair, and exocytosis. The large size of ferlin proteins and the lack of consensus regarding domain boundaries have slowed progress in understanding molecular-lev
Externí odkaz:
https://doaj.org/article/963002a30b464c2c9ce1863e9f93ae45
Autor:
Nazmul H Khan, Anthony A Bui, Yang Xiao, R Bryan Sutton, Robert W Shaw, Benjamin J Wylie, Michael P Latham
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214440 (2019)
The hydrolysis of β-lactam antibiotics by β-lactamase enzymes is the most prominent antibiotic resistance mechanism for many pathogenic bacteria. Out of this broad class of enzymes, metallo-β-lactamases are of special clinical interest because of
Externí odkaz:
https://doaj.org/article/b06f4fd85931481b978be919b54b1ff1
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110152- (2024)
Summary: The mouse epididymis is a long tubule connecting the testis to the vas deferens. Its primary functions are to mature spermatozoa into motile and fertile cells and to protect them from pathogens that ascend the male tract. We previously demon
Externí odkaz:
https://doaj.org/article/ba88ca6aa0d94f4a98537c517fb04e0a
Autor:
Michael E Fealey, Jacob W Gauer, Sarah C Kempka, Katie Miller, Kamakshi Nayak, R Bryan Sutton, Anne Hinderliter
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46748 (2012)
Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has c
Externí odkaz:
https://doaj.org/article/636971064df94cd5aafbb4edaf9752e4
Autor:
Robert D Lagow, Hong Bao, Evan N Cohen, Richard W Daniels, Aleksej Zuzek, Wade H Williams, Gregory T Macleod, R Bryan Sutton, Bing Zhang
Publikováno v:
PLoS Biology, Vol 5, Iss 4, p e72 (2007)
Both constitutive secretion and Ca(2+)-regulated exocytosis require the assembly of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes. At present, little is known about how the SNARE complexes mediating these
Externí odkaz:
https://doaj.org/article/4cf400d1f8444216b93189a1ea0713bc
Autor:
R. Bryan Sutton
Publikováno v:
Southwest Respiratory and Critical Care Chronicles, Vol 6, Iss 23, Pp 1-3 (2018)
Externí odkaz:
https://doaj.org/article/aeb383cf9f6c4fc7b47c7de710e159f2
Autor:
Isaac L. Scott, Matthew J. Dominguez, Adam Snow, Faraz M. Harsini, Justin Williams, Kerry L. Fuson, Roshan Thapa, Pushpak Bhattacharjee, Gail A. Cornwall, Peter A. Keyel, R. Bryan Sutton
Publikováno v:
bioRxiv
Limb-Girdle Muscular Dystrophy Type-2B/2R is caused by mutations in thedysferlingene (DYSF). This disease has two known pathogenic missense mutations that occur within dysferlin’s C2A domain, namely C2AW52Rand C2AV67D. Yet, the etiological rational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86334900b6dfa65d722438b3336c834
https://doi.org/10.1101/2023.04.24.538129
https://doi.org/10.1101/2023.04.24.538129
Autor:
Minal Engavale, Colton J. Hernandez, Angelica Infante, Tanya LeRoith, Elliott Radovan, Lauryn Evans, Johanna Villarreal, Christopher M. Reilly, R. Bryan Sutton, Peter A. Keyel
Publikováno v:
bioRxiv
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease caused by environmental factors and loss of key proteins. One such protein is a serum endonuclease secreted by macrophages and dendritic cells, Dnase1L3. Loss of Dnase1L3 causes pedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937d5f8772081ec4326a9660e59b4b30
https://doi.org/10.1101/2023.04.17.537232
https://doi.org/10.1101/2023.04.17.537232
Autor:
Chi Wang, Zhengrong Yang, Blaine J. Loughlin, Haijin Xu, Guido Veit, Sergey Vorobiev, Oliver B. Clarke, Fan Jiang, Yaohui Li, Shikha Singh, Zachary Rich, Elizabeth R. Menten, Robert A. Grassucci, Wei Wang, Allison Mezzell, Ziao Fu, Kam-Ho Wong, Jing Wang, Diana R. Wetmore, R. Bryan Sutton, Christie G. Brouillette, Ina L. Urbatsch, John C. Kappes, Gergely L. Lukacs, Joachim Frank, John F. Hunt
Cystic fibrosis (CF) is caused by mutations in a chloride channel called the human Cystic Fibrosis Transmembrane Conductance Regulator (hCFTR). We used cryo-EM global conformational ensemble reconstruction to characterize the mechanism by which the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8099769d8252d91e0952af46cc5ab09
https://doi.org/10.1101/2022.10.10.510913
https://doi.org/10.1101/2022.10.10.510913
Autor:
Minal Engavale, Peter Keyel, Elisabeth Bengtson, R. Bryan Sutton, Jon J. McCord, Britney Mapp, Nadine Nzimulinda
Publikováno v:
Encyclopedia, Vol 1, Iss 44, Pp 527-541 (2021)
The deoxyribonuclease 1 (Dnase1) family is a key family of endonucleases that degrades DNA. Loss of Dnase1 family function causes several diseases where the host’s immune system targets the host, such as systemic lupus erythematosus, hypocomplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d178abfd46bbf35ff5fb84f3afea489b
https://www.mdpi.com/2673-8392/1/3/44
https://www.mdpi.com/2673-8392/1/3/44