Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R Bryan Klassen"'
Autor:
Rong Chen, Tara K Sigdel, Li Li, Neeraja Kambham, Joel T Dudley, Szu-Chuan Hsieh, R Bryan Klassen, Amery Chen, Tuyen Caohuu, Alexander A Morgan, Hannah A Valantine, Kiran K Khush, Minnie M Sarwal, Atul J Butte
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 9 (2010)
Serum proteins are routinely used to diagnose diseases, but are hard to find due to low sensitivity in screening the serum proteome. Public repositories of microarray data, such as the Gene Expression Omnibus (GEO), contain RNA expression profiles fo
Externí odkaz:
https://doaj.org/article/c16fd1e3c503408e8ee6fe32abfe142e
Autor:
L. G. Navar, Patricia L. Allen, Timothy G. Hammond, Kelly Johanson, R. Bryan Klassen, Chasity B. Baker, Romer A. Gonzalez-Villalobos, Hiroyuki Kobori
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F1270-F1275
Megalin is a multiligand receptor heavily involved in protein endocytosis. We recently demonstrated that megalin binds and mediates internalization of ANG II. Although there is a strong structural resemblance between ANG II and ANG-(1–7), their phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c6f052d439802f360799af10e574de
https://doi.org/10.1152/ajprenal.00164.2005
https://doi.org/10.1152/ajprenal.00164.2005
Autor:
Renata Kozyraki, Pierre J. Verroust, Patricia L. Allen, R. Bryan Klassen, Laura Tío, Kimberly Crenshaw, Timothy G. Hammond, Sílvia Atrian
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F393-F403
Although several heavy metal toxins are delivered to the kidney on the carrier protein metallothionein (MT), uncertainty as to how MT enters proximal tubular cells limits treatment strategies. Prompted by reports that MT-I interferes with renal uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c9d2238d7cd1905074a6096a7578c9
https://doi.org/10.1152/ajprenal.00233.2003
https://doi.org/10.1152/ajprenal.00233.2003
Publikováno v:
Organometallics. 16:3623-3627
Copper-free [Ag(PBu3)I]4 (1†) promotes the reaction of n-butylmagnesium chloride with 2-cyclohexen-1-one at −45 °C to produce 3-butylcyclohexanone. n-Butyllithium affords comparable results at −78 °C. Notably, compound 1† effects a stoichio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564aeda7f93972a5bac53cfb8169431e
https://doi.org/10.1021/om9700728
https://doi.org/10.1021/om9700728
Publikováno v:
Advances in clinical chemistry. 47
Publication of the human proteome has prompted efforts to develop high-throughput techniques that can catalogue and quantify proteins and peptides present in different tissue types. The field of proteomics aims to identify, quantify, analyze, and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a25cae20279407f370cedcf9b269ef31
https://pubmed.ncbi.nlm.nih.gov/19634780
https://pubmed.ncbi.nlm.nih.gov/19634780
Publication of the human proteome has prompted efforts to develop high-throughput techniques that can catalogue and quantify proteins and peptides present in different tissue types. The field of proteomics aims to identify, quantify, analyze, and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c01acb0f1bddbb0d09cc28382a07bca3
https://doi.org/10.1016/s0065-2423(09)47006-9
https://doi.org/10.1016/s0065-2423(09)47006-9
Publikováno v:
Organometallics. 9:3178-3181
The enantioselective conjugate addition of Grignard reagents to enones catalyzed by copper (I) complexes with bidentate chiral auxiliary ligands, N,N'-dialkyl-substituted aminotropone iminates has been studied. The enantioselectivity of the reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::487f07583d6ea414ef1866becea3b82e
https://doi.org/10.1021/om00162a032
https://doi.org/10.1021/om00162a032
Autor:
Romer Gonzalez-Villalobos, R. Bryan Klassen, Patricia L. Allen, L. G. Navar, Timothy G. Hammond
Publikováno v:
American journal of physiology. Renal physiology. 288(2)
Megalin is an abundant membrane protein heavily involved in receptor-mediated endocytosis. The major functions of megalin in vivo remain incompletely defined as megalin typically faces specialized milieus such as glomerular filtrate, airways, epididy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ab1d6a535cdb0372a98bb5cacbccb8
https://pubmed.ncbi.nlm.nih.gov/15467006
https://pubmed.ncbi.nlm.nih.gov/15467006
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 98(1)
Cubilin and megalin are giant glycoprotein receptors abundant on the luminal surface of proximal tubular cells of the kidney. We showed previously that light chains are a ligand for cubilin. As cubilin and megalin share a number of common ligands, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bf0875a9f5619d5301ebc9d99ee61d
https://pubmed.ncbi.nlm.nih.gov/15286052
https://pubmed.ncbi.nlm.nih.gov/15286052