Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R Brent Thomson"'
Autor:
Nicolas Cornière, R Brent Thomson, Stéphanie Thauvin, Bruno O Villoutreix, Sophie Karp, Diane W Dynia, Sarah Burlein, Lennart Brinkmann, Alaa Badreddine, Aurélie Dechaume, Mehdi Derhourhi, Emmanuelle Durand, Emmanuel Vaillant, Philippe Froguel, Régine Chambrey, Peter S Aronson, Amélie Bonnefond, Dominique Eladari
Publikováno v:
Journal of Medical Genetics. 59:1035-1043
BackgroundNephrolithiasis (NL) is a complex multifactorial disease affecting up to 10%–20% of the human population and causing a significant burden on public health systems worldwide. It results from a combination of environmental and genetic facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6b64342b58674b35aa84ff0d5dd64
https://doi.org/10.1136/jmedgenet-2021-108256
https://doi.org/10.1136/jmedgenet-2021-108256
Publikováno v:
The Journal of urology. 197(2)
The brush border Cl−-oxalate exchanger SLC26A6 plays an essential role in mediating intestinal secretion of oxalate and is crucial for the maintenance of oxalate homeostasis and the prevention of hyperoxaluria and calcium oxalate nephrolithiasis. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903e24023dc5982b61fe075ba29312df
https://pubmed.ncbi.nlm.nih.gov/27681177
https://pubmed.ncbi.nlm.nih.gov/27681177
Autor:
Stefan Somlo, Eric Delpire, Karen Earle, R. Brent Thomson, Peter S. Aronson, SueAnn Mentone, Robert Kim
Publikováno v:
American Journal of Physiology-Renal Physiology. 285:F870-F880
It has been proposed that autosomal dominant polycystic kidney disease (ADPKD)affected renal epithelial cells undergo a phenotypic transition from a highly differentiated absorptive state to a much less differentiated secretory state during cystogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d59a951ec4c7dc317704e7543ca0fb
https://doi.org/10.1152/ajprenal.00153.2003
https://doi.org/10.1152/ajprenal.00153.2003
Autor:
Sue Ann Mentone, Chao Ling Yang, Peter S. Aronson, R. Brent Thomson, Gerhard Giebisch, Felix Knauf
Publikováno v:
Proceedings of the National Academy of Sciences. 98:9425-9430
A key function of the proximal tubule is retrieval of most of the vast quantities of NaCl and water filtered by the kidney. Physiological studies using brush border vesicles and perfused tubules have indicated that a major fraction of Cl − reabsorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47060edc0e16c929ce952e399a40e72
https://doi.org/10.1073/pnas.141241098
https://doi.org/10.1073/pnas.141241098
Autor:
Congyi Li, Peter S. Aronson, Peter Igarashi, Stacey L. Nix, Sharon L. Karp, R. Brent Thomson, Reza Zanjani, Dilys A. Whyte
Publikováno v:
Experts@Minnesota
Kidney-specific cadherin (Ksp-cadherin, cadherin 16) is a novel, kidney-specific member of the cadherin superfamily that is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. To characterize the Ksp-cadherin gene pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c1fd66332372fe7c3d5f8330a2ef58
https://doi.org/10.1152/ajprenal.1999.277.4.f587
https://doi.org/10.1152/ajprenal.1999.277.4.f587
Autor:
R. Brent Thomson, Peter S. Aronson
Publikováno v:
American Journal of Physiology-Renal Physiology. 277:F146-F156
The potential for Ksp-cadherin involvement in either the development or maintenance of the metanephric kidney was assessed by immunocytochemical localization of a monoclonal antibody directed against the rabbit isoform of Ksp-cadherin in both neonata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338aaa0c076fc452cde46f1b6b5f851b
https://doi.org/10.1152/ajprenal.1999.277.1.f146
https://doi.org/10.1152/ajprenal.1999.277.1.f146
Publikováno v:
Journal of Experimental Biology. 155:455-467
The commonly used method of passing short-circuit current (Isc) across insect epithelia through Ag-AgCl electrodes, without the use of salt bridges, leads to significant OH− production at the cathode (lumen side) when high currents are applied. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf02b7d14ad12d5b061473ddc258c632
https://doi.org/10.1242/jeb.155.1.455
https://doi.org/10.1242/jeb.155.1.455
Autor:
Angeliki Louvi, Zhiheng Yu, Sekiya Shibazaki, Stefan Somlo, Michihiro Mitobe, Saori Nishio, Shuta Ishibe, Lloyd G. Cantley, Xin Tian, Peter Igarashi, Heino Velazquez, R. Brent Thomson
Polycystic kidney disease (ADPKD) results from failure of the kidney to properly maintain three-dimensional structure after loss of either polycystin-1 or -2. Mice with kidney selective inactivation of Pkd1 during embryogenesis develop profound renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525f89afb565669c48013ff578b4e0c1
https://europepmc.org/articles/PMC2902289/
https://europepmc.org/articles/PMC2902289/
Autor:
Tong Wang, Luis Tarrats, Benjamin R. Thomson, Peter S. Aronson, Adriana C. C. Girardi, Manoocher Soleimani, SueAnn Mentone, R. Brent Thomson, Olivier Kocher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(37)
Na-H exchanger NHE3 and Cl-anion exchanger CFEX (SLC26A6, PAT1) play principal roles in the reabsorption of Na and Cl in the proximal tubule of the mammalian kidney. The mechanisms by which NHE3 and CFEX are localized to and maintained in the brush b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e257e577280ce423c04df3e44b0256
https://pubmed.ncbi.nlm.nih.gov/16141316
https://pubmed.ncbi.nlm.nih.gov/16141316
Autor:
R. Brent Thomson, Martin Susani, Peter R. Mazal, Sigurd Krieger, Peter S. Aronson, Andrea Haitel, Markus Exner
Publikováno v:
Human pathology. 36(1)
Distinguishing renal oncocytoma from chromophobe and other renal carcinomas is essential, considering their differing biological potentials. Although renal oncocytoma is considered a benign tumor, chromophobe renal cell carcinoma has potentially mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad108a32ef1a3f9dd73a3904cdc707b
https://pubmed.ncbi.nlm.nih.gov/15712178
https://pubmed.ncbi.nlm.nih.gov/15712178