Zobrazeno 1 - 10
of 1 124
pro vyhledávání: '"R Behr"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Using ex vivo microscopy, virtual pathology can improve histological procedures by providing pathology images in near real-time without tissue destruction. Several emerging and promising approaches leverage fast-acting small-molecule fluores
Externí odkaz:
https://doaj.org/article/f020897b02c848c1ad078cfe8f31a4d1
Autor:
C. Anwar A. Chahal, David J. Tester, Ahmed U. Fayyaz, Keerthi Jaliparthy, Nadeem A. Khan, Dongmei Lu, Mariha Khan, Aradhana Sahoo, Aiswarya Rajendran, Jennifer A. Knight, Michael A. Simpson, Elijah R. Behr, Elson L. So, Erik K. St. Louis, R. Ross Reichard, William D. Edwards, Michael J. Ackerman, Virend K. Somers
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021)
Background Sudden cardiac arrest is the leading mode of death in the United States. Epilepsy affects 1% of Americans; yet epidemiological data show a prevalence of 4% in cases of sudden cardiac arrest. Sudden unexpected death in epilepsy (SUDEP) may
Externí odkaz:
https://doaj.org/article/1ce33c1a26ed48f499265cf0a37d1956
Autor:
Hariharan Raju, James S. Ware, Jonathan R. Skinner, Paula L. Hedley, Gavin Arno, Donald R. Love, Christian van der Werf, Jacob Tfelt-Hansen, Bo Gregers Winkel, Marta C. Cohen, Xinzhong Li, Shibu John, Sanjay Sharma, Steve Jeffery, Arthur A. M. Wilde, Michael Christiansen, Mary N. Sheppard, Elijah R. Behr
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background We aimed to determine the mutation yield and clinical applicability of “molecular autopsy” following sudden arrhythmic death syndrome (SADS) by validating and utilizing low-cost high-throughput technologies: Fluidigm Access Ar
Externí odkaz:
https://doaj.org/article/dcacc9ba179d4d699a6d0ada9f7f32ac
Publikováno v:
Primate Biology, Vol 6, Pp 75-86 (2019)
Clinical application of regenerative therapies using embryonic or induced pluripotent stem cells is within reach. Progress made during recent years has encouraged researchers to address remaining open questions in order to finally translate experimen
Externí odkaz:
https://doaj.org/article/40bce257b9ad45efa9e1bdde0fbe451f
Autor:
Chris Miles, Bastiaan J. Boukens, Chiara Scrocco, Arthur A.M. Wilde, Koonlawee Nademanee, Michel Haissaguerre, Ruben Coronel, Elijah R. Behr
Publikováno v:
Circulation, 147(21), 1622-1633. Lippincott Williams and Wilkins
Brugada syndrome (BrS), early repolarization syndrome (ERS), and idiopathic ventricular fibrillation (iVF) have long been considered primary electrical disorders associated with malignant ventricular arrhythmia and sudden cardiac death. However, rece
Autor:
Giuseppe Ciliberti, Joseph Westaby, Michael Papadakis, Elijah R. Behr, Sanjay Sharma, Gherardo Finocchiaro, Mary N. Sheppard
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:787-792
Background: Spontaneous coronary artery dissection (SCAD) and myocardial infarction with nonobstructed coronary arteries (MINOCA) are increasingly recognized causes of acute coronary syndrome and potentially of sudden cardiac death (SCD). SCAD has be
Autor:
Kevin R. Bersell, Tao Yang, Jonathan D. Mosley, Andrew M. Glazer, Andrew T. Hale, Dmytro O. Kryshtal, Kyungsoo Kim, Jeffrey D. Steimle, Jonathan D. Brown, Joe-Elie Salem, Courtney C. Campbell, Charles C. Hong, Quinn S. Wells, Amanda N. Johnson, Laura Short, Marcia A. Blair, Elijah R. Behr, Evmorfia Petropoulou, Yalda Jamshidi, Mark D. Benson, Michelle J. Keyes, Debby Ngo, Ramachandran S. Vasan, Qiong Yang, Robert E. Gerszten, Christian Shaffer, Shan Parikh, Quanhu Sheng, Prince J. Kannankeril, Ivan P. Moskowitz, John D. York, Thomas J. Wang, Bjorn C. Knollmann, Dan M. Roden
Publikováno v:
Circulation. 147:824-840
Background: Brugada syndrome (BrS) is an inherited arrhythmia syndrome caused by loss-of-function variants in the cardiac sodium channel gene SCN5A (sodium voltage-gated channel alpha subunit 5) in ≈20% of subjects. We identified a family with 4 in
Publikováno v:
Primate Biology, Vol 4, Pp 231-240 (2017)
The protein c-CBL is a ubiquitin ligase. It catalyzes the last step of the transfer of ubiquitin to target proteins. Upon completion of polyubiquitination, the target proteins are degraded. Clinically, it is important that c-CBL is mutated in a su
Externí odkaz:
https://doaj.org/article/98b1bde1478644808ada660e5b44cc80
Autor:
Y Wijeyeratne, M W Tanck, P P Mckeown, V Probst, L Crotti, S Page, J Galvin, E Petzer, M Horie, D Roden, C Veltmann, N Makita, T Aiba, M J Ackerman, E R Behr
Publikováno v:
Europace. 25
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): National Institute of Health Research St George's, University of London Background SCN5A-E1784K (c.5350G>A) is the most common variant associated with th
Autor:
Richard Saumarez, John Silberbauer, Jack Scannell, Mariusz Pytkowski, Elijah R Behr, Timothy Betts, Paulo Della Bella, Nicholas S Peters
Publikováno v:
EP Europace.
While sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) is due to arrhythmias, the guidelines for prediction of SCD are based solely on non-electrophysiological methods. This study aims to stimulate thinking about whether the interests