Zobrazeno 1 - 10
of 361
pro vyhledávání: '"R Beers"'
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 24, Pp 1357-1379 (2024)
Moderate- or high-severity fires promote increases in runoff and erosion, leading to a greater likelihood of extreme geomorphic responses, including debris flows. In the first several years following fire, the majority of debris flows initiate when r
Externí odkaz:
https://doaj.org/article/2b219707d56a4ce387f15e9cd206aae2
Autor:
Jason R. Thonhoff, David R. Beers, Weihua Zhao, Alireza Faridar, Aaron Thome, Shixiang Wen, Aijun Zhang, Jinghong Wang, Stanley H. Appel
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectiveTo determine whether a combination therapy with abatacept (CTLA4-Ig) and interleukin-2 (IL-2) is safe and suppresses markers of oxidative stress, inflammation, and degeneration in ALS.MethodsIn this open-label study, four participants with A
Externí odkaz:
https://doaj.org/article/23b3a503a45b412f8431ba1083024eb8
Autor:
Brad G. Kurowski, Amery Treble-Barna, Valentina Pilipenko, Lisa J. Martin, Anil G. Jegga, Aimee E. Miley, Nanhua Zhang, Anthony Fabio, Ranjit S. Chima, Anna-Lynne R. Adlam, Kenneth Kaufman, Michael J. Bell, Sue R. Beers, Stephen R. Wisniewski, Shari L. Wade, TBI Genetics and Environment Study Team
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Introduction: There is significant unexplained variability in behavioral and executive functioning after pediatric traumatic brain injury (TBI). Prior research indicates that there are likely genetic contributions; however, current research is limite
Externí odkaz:
https://doaj.org/article/ef70d6c38f6e4c31b24d60c6d0614514
Autor:
Alireza Faridar, Abdulmunaim M. Eid, Aaron D. Thome, Weihua Zhao, David R. Beers, Maria B. Pascual, Mohammad O. Nakawah, Gustavo C. Roman, Charles S. Davis, Michael Grundman, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-4 (2023)
Trial registration ClinicalTrials.gov Identifier: NCT05821153, Registered April 20 2023, Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05821153
Externí odkaz:
https://doaj.org/article/e8a0ebe6290e4359b7e72393eaf523ef
Autor:
F. K. Rengers, L. A. McGuire, K. R. Barnhart, A. M. Youberg, D. Cadol, A. N. Gorr, O. J. Hoch, R. Beers, J. W. Kean
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 23, Pp 2075-2088 (2023)
Debris flows transport large quantities of water and granular material, such as sediment and wood, and this mixture can have devastating effects on life and infrastructure. The proportion of large woody debris (LWD) incorporated into debris flows can
Externí odkaz:
https://doaj.org/article/7b150d5c7b114224ba08817d2c88e191
Autor:
Alireza Faridar, Matthew Vasquez, Aaron D. Thome, Zheng Yin, Hui Xuan, Jing Hong Wang, Shixiang Wen, Xuping Li, Jason R. Thonhoff, Weihua Zhao, Hong Zhao, David R. Beers, Stephen T. C. Wong, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions. We previously documented that Treg immunomodulatory mechanisms are comp
Externí odkaz:
https://doaj.org/article/52b183fb078941b9b217ebdf26d36db7
Autor:
Aaron D. Thome, Farah Atassi, Jinghong Wang, Alireza Faridar, Weihua Zhao, Jason R. Thonhoff, David R. Beers, Eugene C. Lai, Stanley H. Appel
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Inflammation is a pathological hallmark of Parkinson’s disease (PD). Chronic pro-inflammatory responses contribute to the loss of neurons in the neurodegenerative process. The present study was undertaken to define the peripheral innate an
Externí odkaz:
https://doaj.org/article/31fbf101a5d54be486190d6c220e76d4
Autor:
Aaron D. Thome, Jason R. Thonhoff, Weihua Zhao, Alireza Faridar, Jinghong Wang, David R. Beers, Stanley H. Appel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Extracellular vehicles (EVs) are efficient biomarkers of disease and participate in disease pathogenesis; however, their use as clinical therapies to modify disease outcomes remains to be determined. Cell-based immune therapies, including regulatory
Externí odkaz:
https://doaj.org/article/d4950a1a2da241859872c70b9fd4dbf0
Autor:
Daryaneh Badaly, Sue R. Beers, Rafael Ceschin, Vincent K. Lee, Shahida Sulaiman, Alexandria Zahner, Julia Wallace, Aurélia Berdaa-Sahel, Cheryl Burns, Cecilia W. Lo, Ashok Panigrahy
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectiveChildren, adolescents, and young adults with congenital heart defects (CHD) often display executive dysfunction. We consider the prefrontal and cerebellar brain structures as mechanisms for executive dysfunction among those with CHD.Methods5
Externí odkaz:
https://doaj.org/article/0f7496d2e3c844899b16920152b6beeb
Autor:
Vanessa J. Schmithorst, Phillip S. Adams, Daryaneh Badaly, Vincent K. Lee, Julia Wallace, Nancy Beluk, Jodie K. Votava-Smith, Jacqueline G. Weinberg, Sue R. Beers, Jon Detterich, John C. Wood, Cecilia W. Lo, Ashok Panigrahy
Publikováno v:
Metabolites, Vol 12, Iss 9, p 882 (2022)
We use a non-invasive MRI proxy of neurovascular function (pnvf) to assess the ability of the vasculature to supply baseline metabolic demand, to compare pediatric and young adult congenital heart disease (CHD) patients to normal referents and relate
Externí odkaz:
https://doaj.org/article/17726992aced489aa5e633331545cf73