Zobrazeno 1 - 10 of 125 pro vyhledávání: '"R B Nussenblatt"'
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Interferon-β and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling
Autor: Kozaburo Hayashi, M. T. Lee, R. B. Nussenblatt, L.C. Hooper, Barbara Detrick, Leila I. Kump, John J. Hooks
Publikováno v: Clinical and Experimental Immunology. 147:71-80
Summary Retinal vasculitis is a major component of ocular inflammation that plays a role in retinal tissue damage in patients with idiopathic uveitis and Behçet's disease. Here we show that type 1 interferons (IFN α/β) were not detected in sera fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac8aa1b32628695405dfaf365223715
https://doi.org/10.1111/j.1365-2249.2006.03253.x
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2
Iris Involvement in Primary Intraocular Lymphoma
Autor: De Smet, Gisela Velez, R. B. Nussenblatt, C.-C. Chan, Scott M. Whitcup, Michael R. Robinson
Publikováno v: Survey of Ophthalmology. 44:518-526
Non-Hodgkin's lymphoma involves ocular tissues either as a primary tumor or as secondary metastasis from systemic disease. Diagnosis is based on the identification of malignant cells in the eye by biopsy. Although primary intraocular lymphoma cells h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caa294b6ea5f762e0508791cfb175f04
https://doi.org/10.1016/s0039-6257(00)00118-1
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3
Human Lymphocyte Responses against Epitopes of a Self Antigen: A Follow-up at Different Time Points
Autor: Joseph Shiloach, Atsuki Fukushima, R. B. Nussenblatt, Scott M. Whitcup, Igal Gery
Publikováno v: Cellular Immunology. 167:150-153
This study was aimed at examining the changes that may occur with time in the lymphocyte responses of an individual against peptide determinants of self antigens. Peripheral blood lymphocytes were collected from the same donor at seven different time
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6c20b84fee5e847f884f12d4912d91
https://doi.org/10.1006/cimm.1996.0019
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4
Periocular inflammation in mice with experimental systemic lupus erythematosus. A new experimental blepharitis and its modulation
Autor: C C Chan, I Gery, L D Kohn, R B Nussenblatt, E Mozes, D S Singer
Publikováno v: The Journal of Immunology. 154:4830-4835
Experimental systemic lupus erythematosus (SLE) can be induced in mice by immunization with a human monoclonal anti-DNA Ab, bearing a major Id 16/6Id. Immunized mice initially produce Abs to 16/6Id, DNA and nuclear Ags, and subsequently develop vario
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11388f46290dafabe09703f016d8ae88
https://doi.org/10.4049/jimmunol.154.9.4830
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5
Synergistic effect of rapamycin and cyclosporin A in the treatment of experimental autoimmune uveoretinitis
Autor: D F Martin, L R DeBarge, R B Nussenblatt, C C Chan, F G Roberge
Publikováno v: The Journal of Immunology. 154:922-927
Immunosuppressive drugs currently available for the treatment of autoimmune diseases display a narrow therapeutic window between efficacy and toxic side effects. The use of combinations of drugs that have a synergistic effect may expand this window a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fa573421e95f4e456583240a828fbb9
https://doi.org/10.4049/jimmunol.154.2.922
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6
Intraocular Lymphoma
Autor: M. D. de Smet, Miguel Burnier, Alan G. Palestine, Scott M. Whitcup, Daniel F. Martin, Chi-Chao Chan, Benjamin I. Rubin, R. B. Nussenblatt
Publikováno v: Ophthalmology. 100:1399-1406
Background: Intraocular lymphoma is associated with significant morbidity and mortality, but early diagnosis and treatment may improve prognosis. Methods: The diagnostic features of 12 cases of intraocular lymphoma diagnosed at the National Eye Insti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df1279c743036c3abf5fd0b6b8564c7f
https://doi.org/10.1016/s0161-6420(93)31469-7
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7
Evidence for selective accumulation of V beta 8+ T lymphocytes in experimental autoimmune uveoretinitis induced with two different retinal antigens
Autor: C E Egwuagu, R M Mahdi, R B Nussenblatt, I Gery, R R Caspi
Publikováno v: The Journal of Immunology. 151:1627-1636
Experimental autoimmune uveoretinitis (EAU) is a T cell-mediated autoimmune disease that serves as a model of human intraocular inflammatory disease (uveitis) and is initiated in susceptible animals by immunization with retinal Ag, such as interphoto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184a014efdbd695ec1f30af990bb8280
https://doi.org/10.4049/jimmunol.151.3.1627
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8
Monoclonal Antibodies against ICAM-1 (CD54) and LFA-1 (CD11a/CD18) Inhibit Experimental Autoimmune Uveitis
Autor: Scott M. Whitcup, R. B. Nussenblatt, Chi-Chao Chan, R. Harning, L. R. Debarge, Rachel R. Caspi
Publikováno v: Clinical Immunology and Immunopathology. 67:143-150
Cell adhesion molecules are surface proteins important for cell migration and adhesion and are strongly expressed in eyes with inflammation. We studied the expression of two cell adhesion molecules: intercellular adhesion molecule-1 (ICAM-1, CD54) an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f537e842fa2ce10fbd590585f60f62
https://doi.org/10.1006/clin.1993.1057
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