Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R B Lobell"'
Publikováno v:
The Journal of Immunology. 152:811-818
Mouse IL-3-dependent, bone marrow culture-derived mast cells (BMMC) bind IgG immune complexes through Fc receptors for IgG (Fc gamma R) but express minimal Fc gamma RIII on their surfaces. BMMC do not degranulate appreciably when their Fc gamma R are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ead3999ec687dab93a268321ee726e45
https://doi.org/10.4049/jimmunol.152.2.811
https://doi.org/10.4049/jimmunol.152.2.811
Publikováno v:
Journal of Biological Chemistry. 268:1207-1212
Although mouse interleukin-3-dependent, bone marrow culture-derived progenitor mast cells (BMMC) and a Kirsten sarcoma virus (KiSV)-immortalized mouse mast cell line (MC4w) both express on their surfaces receptors for the Fc portion of IgG (Fc gamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd209eaefaf2353b2544faffddfd851
https://doi.org/10.1016/s0021-9258(18)54061-8
https://doi.org/10.1016/s0021-9258(18)54061-8
Autor:
B W, Trotter, A G, Quigley, W C, Lumma, J T, Sisko, E S, Walsh, C S, Hamann, R G, Robinson, H, Bhimnathwala, D G, Kolodin, W, Zheng, C A, Buser, H E, Huber, R B, Lobell, N E, Kohl, T M, Williams, S L, Graham, C J, Dinsmore
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(7)
A series of 2-arylindole-3-acetamide farnesyl protein transferase inhibitors has been identified. The compounds inhibit the enzyme in a farnesyl pyrophosphate-competitive manner and are selective for farnesyl protein transferase over the related enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1599c354d9826a5883ec39a6ca48202
https://pubmed.ncbi.nlm.nih.gov/11294379
https://pubmed.ncbi.nlm.nih.gov/11294379
Autor:
C A, Omer, Z, Chen, R E, Diehl, M W, Conner, H Y, Chen, M E, Trumbauer, S, Gopal-Truter, G, Seeburger, H, Bhimnathwala, M T, Abrams, J P, Davide, M S, Ellis, J B, Gibbs, I, Greenberg, K S, Koblan, A M, Kral, D, Liu, R B, Lobell, P J, Miller, S D, Mosser, T J, O'Neill, E, Rands, M D, Schaber, E T, Senderak, A, Oliff, N E, Kohl
Publikováno v:
Cancer research. 60(10)
For Ras oncoproteins to transform mammalian cells, they must be posttranslationally modified with a farnesyl group in a reaction catalyzed by the enzyme farnesyl:protein transferase (FPTase). Inhibitors of FPTase have therefore been developed as pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2912ec44ca2d1ecb77982ce053c4c10a
https://pubmed.ncbi.nlm.nih.gov/10825141
https://pubmed.ncbi.nlm.nih.gov/10825141
Autor:
R B, Lobell, N E, Kohl
Publikováno v:
Cancer metastasis reviews. 17(2)
ras is the oncogene most frequently found in human cancers, being detected in 30% of most human cancers and at significantly higher rates in certain cancers including pancreatic (90%) and colon (50%) [1]. Almost 10 years ago it was shown that a C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a02c26d423d978fdfd1f2fa01d55ecf
https://pubmed.ncbi.nlm.nih.gov/9770117
https://pubmed.ncbi.nlm.nih.gov/9770117
Autor:
R B, Lobell
Publikováno v:
Advances in immunology. 68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7afd4dbe9591b4b0380d65b001b6807b
https://pubmed.ncbi.nlm.nih.gov/9505089
https://pubmed.ncbi.nlm.nih.gov/9505089
Autor:
H R, Katz, R B, Lobell
Publikováno v:
International archives of allergy and immunology. 107(1-3)
Activation of mast cells for the release of secretory granule, membrane lipid, and cytokine mediators via Fc gamma R requires cell surface expression of Fc gamma RIII. A soluble factor(s) from fibroblasts up-regulates the surface expression of Fc gam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95725c852bebf083f6d7754b8ef804e9
https://pubmed.ncbi.nlm.nih.gov/7613221
https://pubmed.ncbi.nlm.nih.gov/7613221
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(2)
Mouse IL-3-dependent, bone marrow culture-derived mast cells (BMMC) bind IgG immune complexes through Fc receptors for IgG (Fc gamma R) but express minimal Fc gamma RIII on their surfaces. BMMC do not degranulate appreciably when their Fc gamma R are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e25d1ccb64d042dd58a0e5158f41dfb4
https://pubmed.ncbi.nlm.nih.gov/8283054
https://pubmed.ncbi.nlm.nih.gov/8283054
Publikováno v:
The Journal of biological chemistry. 268(2)
Although mouse interleukin-3-dependent, bone marrow culture-derived progenitor mast cells (BMMC) and a Kirsten sarcoma virus (KiSV)-immortalized mouse mast cell line (MC4w) both express on their surfaces receptors for the Fc portion of IgG (Fc gamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f884af6a918cddea2a2ee7f1577c1801
https://pubmed.ncbi.nlm.nih.gov/8419324
https://pubmed.ncbi.nlm.nih.gov/8419324