Zobrazeno 1 - 10
of 32
pro vyhledávání: '"R B Fitzgeorge"'
Publikováno v:
Infection and Immunity. 63:4224-4230
A virulent strain of Legionella pneumophila serogroup 1, subgroup Pontiac, was grown in continuous culture at a constant growth rate under iron-replete and iron-limited conditions. Iron limitation was achieved by the removal of ferrous sulfate and he
Publikováno v:
Journal of Medical Microbiology. 42:433-441
A new small animal model of experimental Legionnaires' disease is described in which the reconstitution of SCID-Beige mice with human peripheral blood leucocytes permits the in-vivo growth of Legionella pneumophila in the lungs of aerosol-challenged
Publikováno v:
Journal of Antimicrobial Chemotherapy. 31:171-176
The activities of two new macrolides, azithromycin and clarithromycin, were compared in an aerosol-infected guinea-pig model of legionnaires' disease. The results of this study indicate that a low oral dose of azithromycin (3.6 mg/kg) administered on
Publikováno v:
Research in Microbiology. 143:481-488
Transposon Tn5 mutants of L. pneumophila were isolated and screened for loss of virulence-associated characteristics. Three mutants were found with normal ability to produce putative pathogenicity determinants and to be endocytosed by guinea pig alve
Publikováno v:
Journal of Antimicrobial Chemotherapy. 25:101-108
Azithromycin and erythromycin were compared for efficacy in guinea pigs infected with an aerosol containing Legionella pneumophila. When administered intraperitoneally, azithromycin was very effective in the treatment of experimental Legionnaires' di
Publikováno v:
Epidemiology and infection. 112(1)
SummaryAerosol infection (AI) of Porton outbreak mice withListeriaspecies, exhibiting varying degrees of virulence, was compared with gastric intubation (GI) on the basis of numbers of deaths. 50% lethal dose (LD50) and pattern of listerial infection
Publikováno v:
Journal of general microbiology.
The major extracellular enzyme of Legionella pneumophila, a metalloprotease, has been proposed as a pathogenic factor in Legionnaires' disease due to its cytotoxic, tissue-destructive, and phagocyte-inhibitory properties. The relevance of these activ
Publikováno v:
Research in microbiology. 143(5)
Transposon Tn5 mutants of L. pneumophila were isolated and screened for loss of virulence-associated characteristics. Three mutants were found with normal ability to produce putative pathogenicity determinants and to be endocytosed by guinea pig alve
Publikováno v:
The Veterinary record. 130(18)
Hens were exposed to small-particle aerosols containing different concentrations of Salmonella enteritidis phage type 4. They developed a systemic infection and some birds were still excreting the organism in the faeces when killed 28 days after infe
Publikováno v:
Survey of Anesthesiology. :365
We have assessed in vitro the viability of eight species of micro-organism suspended as aerosols and passed through a soda-lime absorber rebreathing system. As had been predicted, the soda-lime exerted a potent cidal effect on non-sporing organisms,