Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R B, Westkaemper"'
Publikováno v:
Molecular pharmacology. 49(1)
Although the beta-adrenergic receptor antagonist (-)-propranolol binds with relatively low affinity at human 5-hydroxytryptamine1D beta receptors (Ki = 10,200 nM), it displays significantly higher affinity (Ki = 17 nM) at its species homolog, 5-HT1B
Publikováno v:
Molecular pharmacology. 47(3)
In this paper we show that a highly conserved aromatic residue, phenylalanine at the 340-position, is essential for ergoline binding to 5-hydroxytryptamine2A receptors. We hypothesized that F340 was essential for a specific aromatic-aromatic interact
Autor:
R B, Westkaemper, R A, Glennon
Publikováno v:
NIDA research monograph. 146
Publikováno v:
Pharmaceutical research. 9(5)
A method is described for the assay of phenobarbital N-glucosylation using UDP-D-[6-3H]glucose. The radioactive phenobarbital N-glucoside conjugates [(5R)-PBG, (5S)-PBG] formed during the incubations were resolved from each other and from uncharacter
Publikováno v:
Pharmaceutical research. 6(6)
The two diastereomers of 1-(1-beta-D-glucopyranosyl)phenobarbital, (1A) and (1B), decompose to 1-(1-beta-D-glucopyranosyl)-3-(2-ethyl-2-phenylmalonyl)urea (2A or 2B) followed by decarboxylation to 1-(1-beta-D-glucopyranosyl)-3-(2-phenylbutyryl)urea (
Autor:
R. P. HANZLIK, R. B. WESTKAEMPER
Publikováno v:
Chemischer Informationsdienst. 11