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Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene. Structure and regulation by cAMP in vitro

Autor: R B, Oonk, K L, Parker, J L, Gibson, J S, Richards

Publikováno v: The Journal of biological chemistry. 265(36)

The entire rat P-450scc gene has been cloned, positions/sequences of the exon-intron boundaries (I-IX) are described and 940 base pairs (bp) of 5'-flanking DNA have been sequenced, compared to mouse, bovine and human genes, and analyzed by functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32d1a58867eecad31a719b41f8dc5bf5
https://pubmed.ncbi.nlm.nih.gov/2176216

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Cyclic AMP-dependent and -independent regulation of cholesterol side chain cleavage cytochrome P-450 (P-450scc) in rat ovarian granulosa cells and corpora lutea. cDNA and deduced amino acid sequence of rat P-450scc

Autor: R B, Oonk, J S, Krasnow, W G, Beattie, J S, Richards

Publikováno v: The Journal of biological chemistry. 264(36)

We report the isolating and sequencing of three cDNA clones encoding rat P-450scc, the nucleotide and protein sequences of which are highly homologous to those of bovine and human P-450scc, especially in the putative heme and steroid binding domains.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7428a98866a6e0a1dfb9858ce54168f
https://pubmed.ncbi.nlm.nih.gov/2480959

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