Výsledky vyhledávání

Characterization of a highly metastatic, orthotopic lung cancer model in the nude rat

Autor: R B, Howard, J B, Mullen, M E, Pagura, M R, Johnston

Publikováno v: Clinicalexperimental metastasis. 17(2)

The prevailing subcutaneous nude rodent tumor xenograft models used for biological and preclinical studies do not optimally reflect some important biological properties of cancer, especially invasion and metastasis. Orthotopic models have been develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::612efb60897febbfca2748cedfd4e31c
https://pubmed.ncbi.nlm.nih.gov/10411108

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Rat ovarian angiotensin II receptors, renin, and angiotensin I-converting enzyme during pregnancy and the postpartum period

Autor: R B, Howard, A, Husain

Publikováno v: Biology of reproduction. 47(6)

The ovarian renin-angiotensin system (RAS) has been studied extensively in the virgin cycling rat, but little information is available about this system in pregnant and postpartum rats. We show that renin and angiotensin I-converting enzyme (ACE)--th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0565eb8416bbcba0d3371628a826da46
https://pubmed.ncbi.nlm.nih.gov/1337275

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Mucin gel formed by tumorigenic squamous lung carcinoma cells has Le(a)-X oligosaccharides and excludes antibodies from underlying cells

Autor: P L, Stranahan, R B, Howard, O, Pfenninger, M E, Cowen, M R, Johnston, D E, Pettijohn

Publikováno v: Cancer research. 52(10)

Cells of cloned lines of human squamous lung carcinomas elaborate large glycoproteins that are associated with their tumorigenic potential. Two groups of clones (called Le(a)-X-positive and Le(a)-X-negative) were studied that either do or do not expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03e271e6ee48f424e3634ada1a5bd717
https://pubmed.ncbi.nlm.nih.gov/1581910

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Lung tolerance to hyperthermia by in vivo perfusion

Autor: R. B. Howard, D. Mulvin, Michael R. Johnston, C. A. Dawson, M. E. Cowen

Publikováno v: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 6(4)

In vivo isolated lung perfusion is a novel technique for targeting anticancer therapy to the lung while avoiding systemic toxicity as normal lung toxicity from the antitumour therapy becomes the limiting factor. This study was performed to investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c016d9383f31cfa82b7216d3b34ed56
https://pubmed.ncbi.nlm.nih.gov/1586490

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Extracellular flush solution that contains blood, mannitol, albumin, and prostacyclin protects rat lungs from six hours of ischemia

Autor: D W, Mulvin, D K, Jones, R B, Howard, M A, Grosso, J E, Repine, M R, Johnston

Publikováno v: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 10(6)

We have used an isolated rat lung model to compare the quality of preservation of different flush techniques with each other and with topical cooling alone. Lung injury was assessed by recording lung weights after reperfusion after 4 and 6 hours of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea4ee3b9afd3bb230099f6eb95aa7c37
https://pubmed.ncbi.nlm.nih.gov/1756165

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Irradiated nude rat model for orthotopic human lung cancers

Autor: R B, Howard, H, Chu, B E, Zeligman, T, Marcell, P A, Bunn, T L, McLemore, D W, Mulvin, M E, Cowen, M R, Johnston

Publikováno v: Cancer research. 51(12)

The development of improved animal models for biological and preclinical studies of human lung cancer is important because lung cancer is the leading cause of cancer death in the United States. To determine whether the Rowett nude rat could serve as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2f85f3279d7515e9d3eb3b61df82f6f
https://pubmed.ncbi.nlm.nih.gov/2040002

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