Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R B, Gartenhaus"'
Autor:
R B Gartenhaus
Publikováno v:
Oncogene. 14:375-378
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western world. Details of the molecular mechanisms involved in the pathogenesis of this leukemia are unclear at present. In other malignancies tumorigenesis has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152d61b5c28216e896de68464169cf1f
https://doi.org/10.1038/sj.onc.1200867
https://doi.org/10.1038/sj.onc.1200867
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
Retinoids, the analogues of vitamin A, have a broad range of effects on different cell types. One biologically active form of vitamin A is all-trans-retinoic acid (ATRA), which binds to retinoic acid receptors, as does its intracellular metabolite, 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e882845fb8af6d1f3045d93e279ca71
https://pubmed.ncbi.nlm.nih.gov/10499631
https://pubmed.ncbi.nlm.nih.gov/10499631
Publikováno v:
Journal of cellular biochemistry. 74(4)
We have recently identified a novel candidate oncogene, MCT-1, in the HUT 78 T-cell line. When overexpressed in NIH3T3 fibroblasts, the MCT-1 gene shortens the G1 phase of the cell cycle and promotes anchorage-independent growth. Progression of cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3110b66d0a531e2a55a7ab348c4c03a5
https://pubmed.ncbi.nlm.nih.gov/10440924
https://pubmed.ncbi.nlm.nih.gov/10440924
Publikováno v:
Cancer research. 58(19)
Using the arbitrarily primed-PCR (AP-PCR) assay to detect genetic abnormalities that occur in a panel of lymphoid cell lines, we identified an amplified stretch of genomic DNA that contained a putative open reading frame. Northern blot analysis with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ae98aef560a9f10ac3420e2767fc348
https://pubmed.ncbi.nlm.nih.gov/9766643
https://pubmed.ncbi.nlm.nih.gov/9766643
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 74(3)
The treatment of chronic lymphocytic leukemia includes the use of alkylating agents, steroids, and more recently nucleoside analogues. While prior studies have described potential mechanisms of 2-chlorodeoxyadenosine cytotoxicity including the accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8082e148e521dabd22754b2be81af028
https://pubmed.ncbi.nlm.nih.gov/8846164
https://pubmed.ncbi.nlm.nih.gov/8846164
Autor:
R B, Gartenhaus, P, Wang
Publikováno v:
Leukemia. 9(12)
Human T cell leukemia virus type-I (HTLV-I), the etiologic agent of adult T cell leukemia (ATL) transforms human T cells in vitro and in vivo. Tax, the major transactivator of HTLV-I is critical for the initial events involved in transformation, howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d62f08709745e6c82d01f0a0a1fbbd9f
https://pubmed.ncbi.nlm.nih.gov/8609720
https://pubmed.ncbi.nlm.nih.gov/8609720