Výsledky vyhledávání - "R B, Gammill"

U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors

Autor: G H, Dillon, H K, Im, B J, Hamilton, D B, Carter, R B, Gammill, T M, Judge, W B, Im

Publikováno v: Molecular pharmacology. 44(4)

We discovered the ability of U-93631 (4-dimethyl-3-t-butylcarboxyl-4,5- dihydro[1,5-a]imidazoquinoxaline) to accelerate decay of gamma-aminobutyric acid (GABA)-induced currents, and we explored its mechanism in human embryonic kidney cells (HEK-293)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf6d7140d2ec8083c23192e648a951e1
https://pubmed.ncbi.nlm.nih.gov/8232235

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Substituted pyrazinones, a new class of allosteric modulators for gamma-aminobutyric acidA receptors

Autor: H K, Im, W B, Im, T M, Judge, R B, Gammill, B J, Hamilton, D B, Carter, J F, Pregenzer

Publikováno v: Molecular pharmacology. 44(2)

We discovered substituted pyrazinones as a new class of allosteric modulators of gamma-aminobutyric acid (GABA)A receptors. Prototype pyrazinones, U-92813 [1-(furfuryl)-3,5-dichloro-6-phenylpyrazinone] and U-94863 [1-benzyl-3,5-dichloro-6-(2-chloroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6285b769e64bfcd32e4402701f00c88
https://pubmed.ncbi.nlm.nih.gov/8018215

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Synthesis of α-Methylene-γ-Butyrolactones

Autor: C. A. Wilson, R. B. Gammill, Thomas A. Bryson

Publikováno v: Synthetic Communications. 5:245-268

The development of natural product synthesis is synonomous with the chemistry of unsaturated carbonyl compounds. Central to numerous steroid, terpene and alkaloid syntheses has been the construction of carbocyclic systems using the conjugated enone f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f51aeeb3aef7a678178c4b9e2b9f4d1
https://doi.org/10.1080/00397917508064119

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A New Synthesis and the13C-NMR OF β-Cyperone 1,3-Dibromo-2-Pentene, A New Ethyl Vinyl Ketone Equivalent

Autor: Thomas A. Bryson, R. B. Gammill

Publikováno v: Synthetic Communications. 6:209-215

In connection with another study underway i n this lab we have been investigating the use of vinylogous thioester 1 as a synthon f o r sesquiterpene synthesis. We have found that 1 is useful for ring annelations and introduction of multiple substitue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f6d3569c0d7b95d2e86d5bf60e74934
https://doi.org/10.1080/00397917608072632

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