Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R B, Effros"'
Autor:
H F, Valenzuela, R B, Effros
Publikováno v:
Methods in molecular medicine. 38
Telomere length measurement can be used both to monitor the proliferation of long-term cultures of somatic cells as well as to determine the replicative history of in vivo-derived cells. The most frequently used technique for telomere length measurem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::852bd8143be748a7fae7115a73cfda5d
https://pubmed.ncbi.nlm.nih.gov/22351265
https://pubmed.ncbi.nlm.nih.gov/22351265
Autor:
R B, Effros
Publikováno v:
Novartis Foundation symposium. 235
Immune system alterations during ageing are complex and pleiotropic, suggestive of remodelling or altered regulation, rather than simple immune deficiency. The most dramatic changes with age occur within the T cell compartment, the arm of the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d625b7b8193dc0c9c2c7d247beae5e8c
https://pubmed.ncbi.nlm.nih.gov/11280023
https://pubmed.ncbi.nlm.nih.gov/11280023
Autor:
R B, Effros
Publikováno v:
Aging (Milan, Italy). 10(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53d78c6a7e0b39742179946565f0930f
https://pubmed.ncbi.nlm.nih.gov/9666205
https://pubmed.ncbi.nlm.nih.gov/9666205
Publikováno v:
Mechanisms of ageing and development. 93(1-3)
Peripheral blood lymphocytes of elderly humans show an increased percentage of T cells with characteristics of replicative senescence. Similarly, the overall decrease in T cell proliferation in aged mice reflects a progressively increasing proportion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c58899b947ce466d67945c35a9382e47
https://pubmed.ncbi.nlm.nih.gov/9089568
https://pubmed.ncbi.nlm.nih.gov/9089568
Publikováno v:
Lymphokine and cytokine research. 10(5)
Aging is correlated with a plethora of immunological changes resulting in both decreased immunity to exogenous antigens and increased autoreactivity. Immunosenescence is generally believed to primarily affect the B- and T-cell compartments, leaving m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf23dc00fda931daafffa57b0edda9a2
https://pubmed.ncbi.nlm.nih.gov/1768737
https://pubmed.ncbi.nlm.nih.gov/1768737
Publikováno v:
Frontiers in Bioscience. 4:d216
Deterioration of the immune system with aging ("immunosenescence") is believed to contribute to morbidity and mortality in man due to the greater incidence of infection, as well as possibly autoimmune phenomena and cancer in the aged. Dysregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4b7465b4b680fba718a2eed7fd5ce0
https://doi.org/10.2741/pawelec
https://doi.org/10.2741/pawelec
Publikováno v:
The Journal of Immunology. 137:1599-1603
In this report, we describe the production and characterization of the first human-human hybridoma secreting antibody to HLA Class II determinants. The hybridoma (GMEC101), which has been stable in tissue culture for greater than 20 mo, secretes 10 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10627f59c7a224f14d0b7e39d43a23ab
https://doi.org/10.4049/jimmunol.137.5.1599
https://doi.org/10.4049/jimmunol.137.5.1599
Publikováno v:
The American journal of pathology. 121(1)
An Epstein-Barr-virus-transformed lymphoblastoid cell line (ECEBV) was derived from a multiply transfused renal dialysis patient. ECEBV was shown to secrete specific antibody in a cellular enzyme-linked immunosorbent assay (CELISA) and was hybridized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49bea3af41c4bb591f7c942b76871b92
https://pubmed.ncbi.nlm.nih.gov/2996358
https://pubmed.ncbi.nlm.nih.gov/2996358
Autor:
R B, Effros, R L, Walford
Publikováno v:
Immunology. 49(2)
Declining immunity in aged individuals has been repeatedly verified. However, many of the studies have focused on functions not directly relevant to the antigens normally encountered in vivo. For example, although infectious agents represent a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3ac1b2424638ec78cc4d7f50764bbc4
https://pubmed.ncbi.nlm.nih.gov/6602091
https://pubmed.ncbi.nlm.nih.gov/6602091
Publikováno v:
Immunology. 35(3)
Mice were first primed with a type A or a type B influenza virus and then challenged intranasally at least 1 month later with another type A virus. Potent cytotoxic T cell populations were found in lung, and effector T cell function was also demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71b9d7a61fc717b0a0db0bd61a4cb03a
https://pubmed.ncbi.nlm.nih.gov/308930
https://pubmed.ncbi.nlm.nih.gov/308930