Zobrazeno 1 - 10
of 92
pro vyhledávání: '"R B, Barlow"'
Publikováno v:
The Biological bulletin. 197(2)
The visual system of the horseshoe crab, Limulus polyphemus, shows a remarkable circadian rhythm in sensitivity. About the time of sunset, a circadian oscillator in the brain of the animal generates efferent optic nerve signals to the lateral eye mod
Publikováno v:
British Journal of Pharmacology. 133:1081-1086
Publikováno v:
British Journal of Pharmacology. 133:1087-1095
If one drug, B, antagonizes another, A, by producing the opposite physiological effect, the antagonist concentration-effect curves should be affected by the recording system, which limits the range of agonist responses. With pieces of isolated guinea
Autor:
H. R. Ing, R. B. Barlow
Publikováno v:
British Journal of Pharmacology. 120:50-56
H.R. (Raymond) Ing was a chemist who developed a unique understanding of pharmacology, which arose from working on alkaloid chemistry. To the chemist he is Ing of the Ing and Manske reaction (for the preparation of primary amines) and responsible for
Publikováno v:
British Journal of Pharmacology. 120:13-18
1. Experiments carried out on guinea-pig isolated ileum with carbachol as agonist and diphenyl-acetoxyethyl-dimethyl-ethyl-ammonium (DADMEA) bromide as antagonist gave results which fit the theoretical relation between fractional inhibition (Q) of th
Autor:
O. Jackson, Daniel S. McQueen, R. B. Barlow, A.G. Branthwaite, Paula J. W. Smith, Kirsten M. Smith, Susan M. Bond
Publikováno v:
British Journal of Pharmacology. 116:2897-2902
1. 4-Diphenylacetoxy-N-cyclohexylmethyl-piperidine HCl (hexahydro-benz-4DAP) is more active as an antagonist of carbachol at receptors in guinea-pig isolated ileum, log K (pA2) = 6.64 +/- 0.14 (s.e. 7 results), than at receptors in guinea-pig isolate
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:1502-1507
The crystal structures of N-benzyl-4-(diphenylacetoxy)piperidine methobromide (I) and hydrobromide (II) and N-(cyclohexylmethyl)-4-(diphenylacetoxy)piperidine hydrochloride (III) were determined. Cations of (I) [N-benzyl-4-(diphenylacetoxy)-N-methylp
Autor:
R. B. Barlow, Susan M. Bond, Anne Paterson, Daniel S. McQueen, J.A.K. Howard, D.W. Holdup, M.A. Veale
Publikováno v:
British Journal of Pharmacology. 106:819-822
1. 4-Diphenylacetoxy-1:1-dimethyl cyclohexane (carbo-4-DAMP) is the carbon analogue of 4-diphenylacetoxy-N-methylpiperidine (4-DAMP) methiodide. The compounds differ only in that the quaternary nitrogen atom in 4-DAMP methiodide is replaced by a quat
Autor:
R B Barlow, Douglas G. McMahon
Publikováno v:
Journal of General Physiology. 100:155-169
We have recorded ocular potentials in response to brief flashes of light from two teleosts, the white perch (Roccus americana) and the green sunfish (Lepomis cyanellus). The animals were respired and maintained in an alert state for up to 2 d. Respon
Publikováno v:
British journal of pharmacology. 133(7)
If one drug, B, antagonizes another, A, by producing the opposite physiological effect, the antagonist concentration-effect curves should be affected by the recording system, which limits the range of agonist responses. With pieces of isolated guinea