Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R B, Baggs"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(6)
Acylases catalyze the hydrolysis of a range of S-substituted N-acetyl-L-cysteines. The hydrolysis of N-acetyl-L-cysteine is catalyzed by cytosolic acylase I, and activity is present in human endothelial cells and rat lung, intestinal, and liver homog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::646923c1ddfa19434797a3772da75c96
https://pubmed.ncbi.nlm.nih.gov/10820133
https://pubmed.ncbi.nlm.nih.gov/10820133
Publikováno v:
Neurotoxicology. 19(6)
Animal studies of the neuropathological effects of prenatal methylmercury (MeHg) seldom use regimens that represent environmental exposures. While acute administration of high doses of MeHg to developing rodents can model some of the outcomes MeHg pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b60a93fa20c4e25839b68cb3340dd47a
https://pubmed.ncbi.nlm.nih.gov/9863776
https://pubmed.ncbi.nlm.nih.gov/9863776
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(1)
Distribution of microsomal glutathione transferase (mGST) protein in rat tissues was investigated by immunohistochemistry. Studies on the localization of mGST are of interest because of its involvement in the detoxication and bioactivation of xenobio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::085aa03a1003d03affc1110dc0a5fe5b
https://pubmed.ncbi.nlm.nih.gov/9010624
https://pubmed.ncbi.nlm.nih.gov/9010624
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(1)
5,6-Dichloro-4-thia-5-hexenoic acid (DCTH) is toxic to rat liver and kidney mitochondria and is cytotoxic to isolated rat hepatocytes. The object of this investigation was to test the hypothesis that DCTH is bioactivated in vivo by the enzymes of mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8659983e48dee8743d97e6fd8c1661c6
https://pubmed.ncbi.nlm.nih.gov/7965751
https://pubmed.ncbi.nlm.nih.gov/7965751
Publikováno v:
Cancer research. 53(11)
The role of the insulin-like growth factor (IGF) receptor in regulating the growth of melanoma cells was evaluated by examining the effect of antibody-mediated IGF receptor inhibition on the growth of four human melanoma cell lines in culture and as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2206ee5395c22634cadbb385058342b8
https://pubmed.ncbi.nlm.nih.gov/8495414
https://pubmed.ncbi.nlm.nih.gov/8495414
Publikováno v:
Contemporary topics in laboratory animal science. 33(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d98eb98806e4157dd33952d4de755db7
https://pubmed.ncbi.nlm.nih.gov/16468687
https://pubmed.ncbi.nlm.nih.gov/16468687
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(3)
The mercapturate S-(2-bromo-2-chloro-1,1-difluoroethyl)-N-acetyl-L-cysteine, which is apparently derived from the halothane degradation product 2-bromo-2-chloro-1,1-difluoroethene, is excreted in urine. S-(2-Bromo-2-chloro-1,1-difluoroethyl)glutathio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c0b3d7dd0f2c0785ccbd3b8123f8509
https://pubmed.ncbi.nlm.nih.gov/1602387
https://pubmed.ncbi.nlm.nih.gov/1602387
Publikováno v:
Cancer research. 52(8)
Mice carrying mutations at the Sl (steel) and W (dominant white spotting) loci develop abnormalities on 3 migratory embryonic stem cell populations: hematopoietic stem cells, neural crest-derived melanocytes, and primordial germ cells. Transplantatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46516b55e847260228d7260d9d187e8a
https://pubmed.ncbi.nlm.nih.gov/1559233
https://pubmed.ncbi.nlm.nih.gov/1559233
Publikováno v:
Cancer research. 51(12)
Diethylstilbestrol (DES) has been associated with vaginal neoplasia and malformations in humans. We have studied a test population of 504 female Wistar rats given diethylstilbestrol at from 0.0 to 0.5 mg/kg maternal body weight on days 18, 19, and 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32826a9ac754ad75a290a2c2c9877af3
https://pubmed.ncbi.nlm.nih.gov/2040004
https://pubmed.ncbi.nlm.nih.gov/2040004