Zobrazeno 1 - 10
of 66
pro vyhledávání: '"R Andrew, Atkinson"'
Autor:
Eva Crosas-Molist, Vittoria Graziani, Oscar Maiques, Pahini Pandya, Joanne Monger, Remi Samain, Samantha L. George, Saba Malik, Jerrine Salise, Valle Morales, Adrien Le Guennec, R. Andrew Atkinson, Rosa M. Marti, Xavier Matias-Guiu, Guillaume Charras, Maria R. Conte, Alberto Elosegui-Artola, Mark Holt, Victoria Sanz-Moreno
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase (AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3-dimensional matrices, fast-migrating amoeboid cancer cells exer
Externí odkaz:
https://doaj.org/article/350286488c1e4475afc3dd506fdbc8ec
Autor:
Daniel S Gutmans, Sara B-M Whittaker, Karishma Asiani, R Andrew Atkinson, Alain Oregioni, Mark Pfuhl
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210352 (2019)
Nek2 is a dimeric serine/ threonine protein kinase that belongs to the family of NIMA-related kinases (Neks). Its N-terminal catalytic domain and its C-terminal regulatory region are bridged by a leucine zipper, which plays an important role in the a
Externí odkaz:
https://doaj.org/article/de49b37a53f24351ba84fd3a4ecaf817
Autor:
Michaeljohn Kalakoutis, Ross D. Pollock, Norman R. Lazarus, R Andrew Atkinson, Marc George, Onur Berber, Roger C. Woledge, Julien Ochala, Stephen D.R. Harridge
Publikováno v:
American Journal of Physiology-Cell Physiology.
Specific force (SF) has been shown to be reduced in some but not all studies of human ageing using chemically skinned single muscle fibres. This may be due in part to the health status/physical activity levels of different older cohorts, but also fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9c5fe41158c7aa221d1614e22e87ab4
https://doi.org/10.1152/ajpcell.00525.2022
https://doi.org/10.1152/ajpcell.00525.2022
Autor:
Michelle T. Ma, Ingebjørg N Hungnes, Fiona Clarke, Paul G. Pringle, Thomas R. Eykyn, Philip J. Blower, Fahad Al-Salemee, Samantha Y.A. Terry, R. Andrew Atkinson, Peter J. Gawne
Publikováno v:
Hungnes, I N, Al-Salemee, F, Gawne, P J, Eykyn, T, Atkinson, R A, Terry, S Y A, Clarke, F, Blower, P J, Pringle, P G & Ma, M T 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging : a versatile diphosphine chelator for 99mTc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/d1dt03177e
Dalton Transactions
Dalton Transactions, Royal Society of Chemistry, 2021, 50 (44), pp.16156-16165. ⟨10.1039/d1dt03177e⟩
Hungnes, I, Al Salemee, F, Gawne, P, Eykyn, T R, Atkinson, A, Terry, S, Clarke, F, Blower, P J, Pringle, P G & Ma, M 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99m Tc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/D1DT03177E
Dalton Transactions
Dalton Transactions, Royal Society of Chemistry, 2021, 50 (44), pp.16156-16165. ⟨10.1039/d1dt03177e⟩
Hungnes, I, Al Salemee, F, Gawne, P, Eykyn, T R, Atkinson, A, Terry, S, Clarke, F, Blower, P J, Pringle, P G & Ma, M 2021, ' One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99m Tc radiolabelling of peptides ', Dalton Transactions, vol. 50, no. 44, pp. 16156-16165 . https://doi.org/10.1039/D1DT03177E
Radiotracers labelled with technetium-99m (99mTc) enable accessible diagnostic imaging of disease, provided that radiotracer preparation is simple. Whilst 99mTc radiopharmaceuticals for imaging perfusion are routinely prepared from kits, and regularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9215b53701872aac69e2b7a2f051abaa
https://hdl.handle.net/1983/fb96ed35-28e8-45e8-8768-7b359c87aac6
https://hdl.handle.net/1983/fb96ed35-28e8-45e8-8768-7b359c87aac6
Autor:
Ingebjørg N, Hungnes, Fahad, Al-Salemee, Peter J, Gawne, Thomas, Eykyn, R Andrew, Atkinson, Samantha Y A, Terry, Fiona, Clarke, Philip J, Blower, Paul G, Pringle, Michelle T, Ma
Publikováno v:
Dalton Transactions (Cambridge, England : 2003)
Radiotracers labelled with technetium-99m (99mTc) enable accessible diagnostic imaging of disease, provided that radiotracer preparation is simple. Whilst 99mTc radiopharmaceuticals for imaging perfusion are routinely prepared from kits, and regularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::919a396fdd0fd9be97ca0f7f4f7c2cfe
https://pubmed.ncbi.nlm.nih.gov/34704995
https://pubmed.ncbi.nlm.nih.gov/34704995
Autor:
Mark R. Holt, Adrien D. Le Guennec, Saba Malik, Oscar Maiques, Victoria Sanz-Moreno, Maria R. Conte, Jerrine Salise, Pahini Pandya, R. Andrew Atkinson, Joanne Monger, Vittoria Graziani, Eva Crosas-Molist, Guillaume Charras
Publikováno v:
SSRN Electronic Journal.
Cell migration is crucial for development, immunity and cancer dissemination. We find that mitochondrial dynamics control plasticity of cell migration by sensing adhesion levels. Amoeboid cells migrating in 3-dimensions (3D) harbour high Myosin II le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d1169f4f6dc6dfcc43c0fbe44b0bc8
https://doi.org/10.2139/ssrn.3845005
https://doi.org/10.2139/ssrn.3845005
Autor:
Maria Takacs, Maxim V Petoukhov, R Andrew Atkinson, Pierre Roblin, François-Xavier Ogi, Borries Demeler, Noelle Potier, Yassmine Chebaro, Annick Dejaegere, Dmitri I Svergun, Dino Moras, Isabelle M L Billas
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67810 (2013)
BackgroundPGC-1α is a crucial regulator of cellular metabolism and energy homeostasis that functionally acts together with the estrogen-related receptors (ERRα and ERRγ) in the regulation of mitochondrial and metabolic gene networks. Dimerization
Externí odkaz:
https://doaj.org/article/0645df87374045a1b9f15e0fba416ec9
Autor:
Zhisheng Lu, Julien R. C. Bergeron, R. Andrew Atkinson, Torsten Schaller, Dennis A. Veselkov, Alain Oregioni, Yi Yang, Stephen J. Matthews, Michael H. Malim, Mark R. Sanderson
Publikováno v:
Open Biology, Vol 3, Iss 11 (2013)
The HIV-1 viral infectivity factor (Vif) neutralizes cell-encoded antiviral APOBEC3 proteins by recruiting a cellular ElonginB (EloB)/ElonginC (EloC)/Cullin5-containing ubiquitin ligase complex, resulting in APOBEC3 ubiquitination and proteolysis. Th
Externí odkaz:
https://doaj.org/article/a0a1999b03a04aa8bcef089b05add5e1
Autor:
Alex F. Drake, Charlotte K. Hind, Richard T. Amison, David A. Phoenix, Alice C. Hodgson-Casson, Tam T. T. Bui, Giorgia Manzo, Clive P. Page, Philip M. Ferguson, Carolyn Lam, J. Mark Sutton, Blaze G O' Shaughnessy, Melanie Clifford, A. James Mason, Bethany J Weller, Christian D. Lorenz, Simon C. Pitchford, Maria Clarke, Rico C. H. Man, Jenny K.W. Lam, Katarzyna A Ciazynska, R. Andrew Atkinson
Publikováno v:
Communications Biology
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-01420-3⟩
Manzo, G, Hind, C K, Ferguson, P, Amison, R, Hodgson-Casson, A, Ciazynska, K, Weller, B, Clarke, M, Lam, C, Man, R, O'Shaughnessy, B, Clifford, M, Bui, T, Drake, A, Atkinson, A, Lam, J, Pitchford, S, Page, C, Phoenix, D, Lorenz, C, Sutton, J M & Mason, J 2020, ' A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy ', Communications Biology, vol. 3, no. 1, 697 . https://doi.org/10.1038/s42003-020-01420-3
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-01420-3⟩
Manzo, G, Hind, C K, Ferguson, P, Amison, R, Hodgson-Casson, A, Ciazynska, K, Weller, B, Clarke, M, Lam, C, Man, R, O'Shaughnessy, B, Clifford, M, Bui, T, Drake, A, Atkinson, A, Lam, J, Pitchford, S, Page, C, Phoenix, D, Lorenz, C, Sutton, J M & Mason, J 2020, ' A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy ', Communications Biology, vol. 3, no. 1, 697 . https://doi.org/10.1038/s42003-020-01420-3
Antimicrobial peptides (AMPs) are a potential alternative to classical antibiotics that are yet to achieve a therapeutic breakthrough for treatment of systemic infections. The antibacterial potency of pleurocidin, an AMP from Winter Flounder, is link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75d65adf0a69c4934578e53063e81e0
https://hal.archives-ouvertes.fr/hal-03030382
https://hal.archives-ouvertes.fr/hal-03030382
Autor:
R. Andrew Atkinson
Publikováno v:
Specialist Periodical Reports Nuclear Magnetic Resonance
Specialist Periodical Reports Nuclear Magnetic Resonance, pp.250-271, 2020, 978-1-78262-998-6. ⟨10.1039/9781788010665-00250⟩
Nuclear Magnetic Resonance ISBN: 9781839167065
Specialist Periodical Reports Nuclear Magnetic Resonance, pp.250-271, 2020, 978-1-78262-998-6. ⟨10.1039/9781788010665-00250⟩
Nuclear Magnetic Resonance ISBN: 9781839167065
A review of key publications from 2020, describing methodological developments and research applications of NMR of proteins and nucleic acids. Particularly novel approaches and reports of exceptional interest are highlighted. Special attention is pai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb8ed0bd94b9ebf7126ea3f4b138472
https://hal.archives-ouvertes.fr/hal-03031969
https://hal.archives-ouvertes.fr/hal-03031969