Výsledky vyhledávání

Akademický článek

NK cells propagate T cell immunity following in situ tumor vaccination

Autor: Won Jong Jin, Justin C. Jagodinsky, Jessica M. Vera, Paul A. Clark, Cindy L. Zuleger, Amy K. Erbe, Irene M. Ong, Trang Le, Kaitlin Tetreault, Tracy Berg, Alexander L. Rakhmilevich, KyungMann Kim, Michael A. Newton, Mark R. Albertini, Paul M. Sondel, Zachary S. Morris

Publikováno v: Cell Reports, Vol 42, Iss 12, Pp 113556- (2023)

Summary: We report an in situ vaccination, adaptable to nearly any type of cancer, that combines radiotherapy targeting one tumor and intratumoral injection of this site with tumor-specific antibody and interleukin-2 (IL-2; 3xTx). In a phase I clinic

Externí odkaz: https://doaj.org/article/3b49ec059cc6419f9fcdd7b1869fd235

Zobrazit plný text záznamu

Akademický článek

Less is more

Autor: R. Alayón, A. Canalda, R. Albertini, J.M. De Gomar, N. Moro

Publikováno v: European Psychiatry, Vol 65, Pp S468-S468 (2022)

Introduction Very few research about atrioventricular blocks (AVB) and use of antipsychotic drugs has been made, although it may play an important role in the outcome of any patient affected by psychosis and AVB. Objectives To describe a case and re

Externí odkaz: https://doaj.org/article/60c44bb7281d498e893a0f2adec66bf6

Zobrazit plný text záznamu

Akademický článek

Immune adverse events (irAEs) with adjuvant ipilimumab in melanoma, use of immunosuppressants and association with outcome: ECOG-ACRIN E1609 study analysis

Autor: F Stephen Hodi, Ahmad A Tarhini, John M Kirkwood, Zeynep Eroglu, Henry B Koon, Ni Kang, Vernon K Sondak, Harriet M Kluger, Sandra J Lee, Gary I Cohen, Laura F Hutchins, Donald P Lawrence, Kari L Kendra, David R Minor, Carrie B Lee, Mark R Albertini, Lawrence E Flaherty, Teresa M Petrella

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)

Background The impact of immune-related adverse events (irAEs) occurring from adjuvant use of immunotherapy and of their management on relapse-free survival (RFS) and overall survival (OS) outcomes is currently not well understood.Patients and method

Externí odkaz: https://doaj.org/article/6f596cfb2e7048f7b2e60a6a21991735

Zobrazit plný text záznamu

Akademický článek

Retrograde Balloon-Assisted Deep Enteroscopy in the Diagnosis of Metastatic Melanoma

Autor: William Barge, Mark R. Albertini, Christopher Cold, Daniel Abbott, Deepak Gopal

Publikováno v: Case Reports in Gastrointestinal Medicine, Vol 2021 (2021)

A 74-year-old male with a history of metastatic melanoma presents with persistently abnormal small bowel findings on PET-CT scan. The patient had persistent FDG uptake near the ileocolic junction on imaging, concerning for metastatic melanoma. Capsul

Externí odkaz: https://doaj.org/article/3703e418ef4e4503b1a7a2a0b49b83f0

Zobrazit plný text záznamu

Akademický článek

Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting.

Autor: Kara Magee, Ian R Marsh, Michelle M Turek, Joseph Grudzinski, Eduardo Aluicio-Sarduy, Jonathan W Engle, Ilene D Kurzman, Cindy L Zuleger, Elizabeth A Oseid, Christine Jaskowiak, Mark R Albertini, Karla Esbona, Bryan Bednarz, Paul M Sondel, Jamey P Weichert, Zachary S Morris, Reinier Hernandez, David M Vail

Publikováno v: PLoS ONE, Vol 16, Iss 8, p e0255798 (2021)

RationaleMurine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the sa

Externí odkaz: https://doaj.org/article/614577853cda400990756e8aa63b13c4

Zobrazit plný text záznamu

Akademický článek

The age of enlightenment in melanoma immunotherapy

Autor: Mark R. Albertini

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-4 (2018)

Abstract An updated survival analysis by Callahan et al. published in the February 1, 2018 issue of the Journal of Clinical Oncology reported a 3-year overall survival (OS) rate of 63% for 94 patients with previously treated or untreated advanced mel

Externí odkaz: https://doaj.org/article/c3576a9b42d54ca892d3be65a2c1d3d6

Zobrazit plný text záznamu

Akademický článek

Multi-model ensemble simulations of olive pollen distribution in Europe in 2014: current status and outlook

Publikováno v: Atmospheric Chemistry and Physics, Vol 17, Pp 12341-12360 (2017)

The paper presents the first modelling experiment of the European-scale olive pollen dispersion, analyses the quality of the predictions, and outlines the research needs. A 6-model strong ensemble of Copernicus Atmospheric Monitoring Service (CAMS

Externí odkaz: https://doaj.org/article/a5198cd9781c43a1823a34ad38bc0499

Zobrazit plný text záznamu