Zobrazeno 1 - 10
of 42
pro vyhledávání: '"R A Yeates"'
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 39:389-394
Concentrations of fluconazole in sebum and plasma were determined in 2 parallel groups, each consisting of 8 healthy subjects. Group 1 received a 150 mg fluconazole capsule once weekly over a period of 4 weeks, Group 2 was administered 2 capsules/wee
Publikováno v:
The Journal of Clinical Pharmacology. 39:1021-1031
The influence of gastrointestinal (GI) transit times on the pharmacokinetics (PK) of three calcium channel blockers (CCBs), recommended for once-daily dosing, was investigated. In a three-way crossover design, the single-dose PK of a controlled-deliv
Publikováno v:
The Journal of Clinical Pharmacology. 38:138-143
The accumulation in scalp hair of the antimycotic triazole, fluconazole, was studied during and after administration. Fluconazole 50 mg was administered to 12 healthy subjects as a single capsule each day for 28 days. The concentration of fluconazole
Publikováno v:
Mycoses. 40:259-265
Fluconazole shows good penetration into the tissues and body fluids examined and a rapid equilibrium is achieved between the concentrations in the various compartments. The pharmacokinetics of fluconazole after intravenous or oral administration are
Publikováno v:
Mycoses. 39:357-360
Summary. Administration of fluconazole in capsule form has proved effective in the prophylaxis and treatment of mucosal candidosis, particularly in immunosuppressed patients. An additional topical effect in oropharyngeal and oesophageal candidosis mi
Publikováno v:
Mycoses. 39:123-126
Zusammenfassung. Die Applikation von Fluconazol-Kapseln hat sich in der Candidose-Therapie und bei immunsupprimierten Patienten zur Candidose-Prophylaxe bewahrt. Von der Darreichungsform einer Fluconazol-Suspension wird ein zusatzlicher topischer Eff
Publikováno v:
Journal of Antimicrobial Chemotherapy. 35:641-647
The pharmacokinetics of a single 100 mg iv dose of fluconazole were studied in parallel groups of ten normal subjects and nine patients with liver cirrhosis, a condition with a high risk of life-threatening fungal infection. The following mean pharma
Publikováno v:
European Journal of Pharmacology. 192:181-184
This study includes the first systematic comparison of an organic nitrate with the corresponding organic nitrite - isobutyl nitrate and isobutyl nitrite. The spasmolytic activity of the nitrite on isolated rabbit aortic strips was stronger, more rapi
Publikováno v:
Infection. 25:192-194
In order to investigate the clinical efficacy of the triazole antifungal agent fluconazole (FCA) in the treatment of pulmonary mycosis, in the present study the concentrations of fluconazole in human pulmonary tissue, pericardial fluid and serum were
Autor:
Marcus E. Martignoni, Beat Gloor, Helmut Friess, Jörg Kleeff, Markus W. Büchler, Shailesh V. Shrikhande, R A Yeates, Huang Yong, Claudia Issenegger
Publikováno v:
Antimicrobial agents and chemotherapy. 44(9)
Because of antibiotic prophylaxis for necrotizing pancreatitis, the frequency of fungal superinfection in patients with pancreatic necrosis is increasing. In this study we analyzed the penetration of fluconazole into the human pancreas and in experim