Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R A Wetsel"'
Publikováno v:
The Journal of Immunology. 159:861-869
The anaphylatoxin C5a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammation in the subarachnoid space. We investigated the expression of the receptor for C5a (C5aR) in brains of mice with experimental Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ed0ce5d7896cea95d928f70946c2dd6
https://doi.org/10.4049/jimmunol.159.2.861
https://doi.org/10.4049/jimmunol.159.2.861
Autor:
X Wang, D T Fleischer, W T Whitehead, D L Haviland, S I Rosenfeld, J P Leddy, R Snyderman, R A Wetsel
Publikováno v:
The Journal of Immunology. 154:5464-5471
Hereditary C5 deficiency has been reported in several families of different ethnic backgrounds and from different geographic regions, but the molecular genetic defect causing C5 deficiency has not been delineated in any of them. To examine the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053922c2454abcd47457bf1fbebcd53b
https://doi.org/10.4049/jimmunol.154.10.5464
https://doi.org/10.4049/jimmunol.154.10.5464
Autor:
D L Haviland, R L McCoy, W T Whitehead, H Akama, E P Molmenti, A Brown, J C Haviland, W C Parks, D H Perlmutter, R A Wetsel
Publikováno v:
The Journal of Immunology. 154:1861-1869
The small-complement C5 activation fragment, C5a, is a potent phlogistic molecule that, on binding to the C5a Receptor (C5aR), mediates contraction of smooth muscle, enhances vascular permeability, and promotes leukocyte functions such as directed ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40171eb27ca9de8d5bbf30a605bda43f
https://doi.org/10.4049/jimmunol.154.4.1861
https://doi.org/10.4049/jimmunol.154.4.1861
Publikováno v:
Parasite immunology. 34(8-9)
Complement contributes to inflammation during pathogen infections; however, less is known regarding its role during malaria and in the severest form of the disease, cerebral malaria. Recent studies have shown that deletion of the complement anaphylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f8e41850687d7f3e448fbe7a986c8c9
https://pubmed.ncbi.nlm.nih.gov/22708514
https://pubmed.ncbi.nlm.nih.gov/22708514
Publikováno v:
The Journal of Immunology. 146:362-368
Two truncated human C5 clones, pHC5A and pHC5B, were isolated from an adult human liver cDNA library, and contained inserts of 2930 and 2181 bp, respectively. Both clones were polyadenylated and encoded the 5'-end of the C5 pro-molecule, thereby comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f4cee2a24c77bc76430ef8292b4e1a
https://doi.org/10.4049/jimmunol.146.1.362
https://doi.org/10.4049/jimmunol.146.1.362
Publikováno v:
Scandinavian journal of immunology. 53(5)
The molecular mechanisms underlying protective granuloma formation and control of bacterial growth during infection with Mycobacterium tuberculosis (MTB) are not yet completely understood. MTB-infected mice with natural deficiency in complement compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f20c3f50a8e4063346430fa614dd5341
https://pubmed.ncbi.nlm.nih.gov/11309154
https://pubmed.ncbi.nlm.nih.gov/11309154
Publikováno v:
Immunology. 93(2)
Deficiency of the complement protein C2 (C2D), one of the most common genetic deficiencies of the complement system, is associated with rheumatological disorders and increased susceptibility to infection. Two types of C2D have been recognized, each i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddaa87d295ae75cab641592f19a358b7
https://pubmed.ncbi.nlm.nih.gov/9616367
https://pubmed.ncbi.nlm.nih.gov/9616367
Autor:
P F, Stahel, K, Frei, H P, Eugster, A, Fontana, K M, Hummel, R A, Wetsel, R S, Ames, S R, Barnum
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(2)
The anaphylatoxin C5a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammation in the subarachnoid space. We investigated the expression of the receptor for C5a (C5aR) in brains of mice with experimental Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dca377851f4311a502f6cff79dee7d4
https://pubmed.ncbi.nlm.nih.gov/9218605
https://pubmed.ncbi.nlm.nih.gov/9218605
Autor:
R A, Wetsel, J, Kulics, M L, Lokki, P, Kiepiela, H, Akama, C A, Johnson, P, Densen, H R, Colten
Publikováno v:
The Journal of biological chemistry. 271(10)
Type II complement protein C2 deficiency is characterized by a selective block in C2 secretion. The Type II C2 null allele (C2Q0) is linked to two major histocompatibility haplotypes (MHC) that differ from the MHC of the more common Type I C2 deficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb135e84a4d89909a11f3b0486d6c40b
https://pubmed.ncbi.nlm.nih.gov/8621452
https://pubmed.ncbi.nlm.nih.gov/8621452
Autor:
X, Wang, D T, Fleischer, W T, Whitehead, D L, Haviland, S I, Rosenfeld, J P, Leddy, R, Snyderman, R A, Wetsel
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(10)
Hereditary C5 deficiency has been reported in several families of different ethnic backgrounds and from different geographic regions, but the molecular genetic defect causing C5 deficiency has not been delineated in any of them. To examine the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a16e57652b556fde8f98fb6ebaace77
https://pubmed.ncbi.nlm.nih.gov/7730648
https://pubmed.ncbi.nlm.nih.gov/7730648