Highlights of the 30th International Conference on Antiviral Research

Autor: Aruna Sampath, R. Anthony Vere Hodge, Kara Carter, E. Bart Tarbet, Zlatko Janeba, José A. Esté, Mike Bray, Luis M. Schang, Graciela Andrei

Publikováno v: Antiviral Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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The 30th International Conference on Antiviral Research (ICAR) was held in Atlanta, GA, USA from May 18 to 21, 2017. This report provides an account of award lectures, invited keynote addresses and oral presentations during the meeting. The 2017 Gert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575fb813897c89f7cff635ab62b7a988
https://doi.org/10.1016/j.antiviral.2017.07.017

Meeting report: 27th International conference on antiviral research, in Raleigh, NC, USA

Autor: R. Anthony Vere Hodge

Publikováno v: Antiviral Research

Highlights • The 27th ICAR was held in Raleigh, NC, USA, May 12–16, 2014. This article summarizes the principal invited lectures. • The Elion Award lecturer recalled the early days of antiviral drugs and how their modes of action were elucidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfc145a186402306ebc01c49b92f4e7

Antiviral agents for herpes simplex virus

Autor: R Anthony, Vere Hodge, Hugh J, Field

Publikováno v: Advances in pharmacology (San Diego, Calif.). 67

This review starts with a brief description of herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), the clinical diseases they cause, and the continuing clinical need for antiviral chemotherapy. A historical overview describes the progress from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8503a80a55b474a003fbfab15cc0b8ac
https://pubmed.ncbi.nlm.nih.gov/23885997

The Mode of Action of Penciclovir

Autor: R. A. Vere Hodge, Yung-Chi Cheng

Publikováno v: Antiviral Chemistry and Chemotherapy. 4:13-24

This review describes the studies that have been carried out to date to investigate the mode of action of penciclovir. Penciclovir is phosphorylated much more efficiently than acyclovir in herpesvirus-infected cells yet the host cell kinases phosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06246640387fbe84ef2cd735bec7a4f0
https://doi.org/10.1177/09563202930040s601

Use of isotopically chiral [4?-13C]famciclovir and13C NMR to identify the chiral monoacetylated intermediates in the conversion of famciclovir to penciclovir by human intestinal wall extract

Autor: Simon A. Readshaw, R. Anthony Vere Hodge, Sarah J. Darlison

Publikováno v: Chirality. 5:577-582

Famciclovir is the oral form of the potent antiherpesvirus agent, penciclovir. Hydrolysis of one of the acetyl ester groups of famciclovir creates a chiral centre leading to the possible formation of (R)- and (S)-enantiomers. During its conversion to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fd810ecccdf74290844dd406e74cb1
https://doi.org/10.1002/chir.530050803