Zobrazeno 1 - 10
of 30
pro vyhledávání: '"R A Stoltz"'
Autor:
Yan Lavrovsky, M. E. Gerritsen, Richard D. Levere, Shigeki Shibahara, M L Schwartzman, Nader G. Abraham, Attallah Kappas, R A Stoltz
Publikováno v:
Proceedings of the National Academy of Sciences. 92:6798-6802
Heme oxygenase (HO) is a stress protein and has been suggested to participate in defense mechanisms against agents that may induce oxidative injury such as metals, endotoxin, heme/hemoglobin, and various cytokines. Overexpression of HO in cells might
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV. 19(4)
Objective To determine the effectiveness and safety of ravuconazole in the treatment of toenail onychomycosis. Design A phase I/II randomized, double-blind, double-dummy, placebo-controlled, dose-ranging study. Four 12-week dosing regimens were used:
Publikováno v:
Investigative ophthalmologyvisual science. 38(10)
Alkali burning of the rabbit cornea is a well-established model for the study of anterior surface inflammation, neovascularization, and wound-healing processes. 12-hydroxyeicosanoids have been implicated as mediators of such responses. 12(S)-hydroxye
Publikováno v:
Current eye research. 16(4)
The RPE is essential in the maintenance of retinal vasculature homeostasis, since increased cellular expression of heme oxygenase-1 (HO-1) has been implicated as a defense mechanism against oxidative stress. This study was done in an effort to determ
Autor:
R. R. Stoltz
Publikováno v:
Landscape Journal. 24:109-110
Autor:
A W, Fox, B W, Sullivan, J D, Buffini, M L, Neichin, R, Nicora, F K, Hoehler, R, O'Rourke, R R, Stoltz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(2)
Sodium dichloroacetate (DCA) or placebo, two infusions 30 min in duration and 8 h apart, was administered to healthy subjects under double-blind conditions. The objectives were to characterize accurately the tolerability of DCA, its pharmacokinetics,
Publikováno v:
Journal of cellular biochemistry. 61(2)
The promoter region of the c-fos oncogene 5' flanking sequence contains enhancer elements crucial for binding nuclear factors that regulate transcription following cell proliferation and differentiation. Single-stranded deoxyoligonucleotides were cho
Autor:
N G, Abraham, J L, da Silva, Y, Lavrovsky, R A, Stoltz, A, Kappas, M W, Dunn, M L, Schwartzman
Publikováno v:
Investigative ophthalmologyvisual science. 36(11)
Heme oxygenase-1 (HO-1) is a stress protein induced up to 100-fold within a few hours after exposure to oxidative stress, and it has been shown to counteract oxidative injury induced by ultraviolet light or free radicals. The current study was undert
Autor:
M S, Conners, R A, Stoltz, S C, Webb, J, Rosenberg, M W, Dunn, N G, Abraham, M, Laniado-Schwartzman
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
To characterize a model of contact lens-induced corneal inflammation in the closed eye, with respect to inflammatory parameters and the metabolism of arachidonic acid by homogenates of the corneal epithelium.Rabbit eyes were fitted with extended wear
Autor:
M S, Conners, R A, Stoltz, K L, Davis, M W, Dunn, N G, Abraham, R D, Levere, M, Laniado-Schwartzman
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
The authors have previously shown a marked increase in corneal epithelial arachidonic acid metabolism to 12-hydroxyeicosatetraenoic acid (12-HETE) and 12-hydroxyeicosatrienoic acid (12-HETrE) in a model of closed eye-contact lens wear. Their formatio