Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R A Roubey"'
Publikováno v:
The Journal of Immunology. 154:954-960
"Anticardiolipin" autoantibodies (aCL) bind to anionic phospholipids only in the presence of beta 2-glycoprotein I (beta 2GPI), a phospholipid-binding plasma protein. The exact role of beta 2GPI in the antigenic specificity of these autoantibodies is
Publikováno v:
The Journal of Immunology. 146:3557-3562
C receptor CR3 (iC3b-receptor, CD11b/CD18) plays an essential role in several phagocytic and adhesive neutrophil functions. Recent evidence suggests that stimulus-induced phosphorylation of the CR3 beta-chain, CD18, may mediate certain neutrophil fun
Autor:
S Minota, W N Jarjour, N Suzuki, Y Nojima, R A Roubey, T Mimura, A Yamada, T Hosoya, F Takaku, J B Winfield
Publikováno v:
The Journal of Immunology. 146:2249-2252
The 110-kDa intracellular phosphoprotein (110K) described previously by this laboratory as a common IgM autoantigen in SLE and certain other systemic autoimmune disorders and viral infections is identified as nucleolin in the present investigation. U
Publikováno v:
The Journal of Immunology. 144:1263-1269
Utilizing nonionic detergent lysates of human lymphoid and non-lymphoid cells as substrate, IgM and/or IgG antibodies to a 110-kDa/isoelectric point 5.4 phosphoprotein (110K) was demonstrated in serum from patients with SLE or certain other systemic
Autor:
Jack R. Harkema, Bruce N. Ames, David B. Peden, James G. Wagner, Qing Jiang, Beate Illek, R. A. Roubey
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 38(3)
Background Traditional therapies for asthma and allergic rhinitis (AR) such as corticosteroids and antihistamines are not without limitations and side effects. The use of complementary and alternative approaches to treat allergic airways disease, inc
Autor:
R A, Roubey
Publikováno v:
Thrombosis and haemostasis. 82(2)
Publikováno v:
British journal of haematology. 105(1)
Antiphospholipid antibodies (aPL), including antibodies detected in anti-cardiolipin (aCL) enzyme-linked immunosorbent assays and in lupus anticoagulant (LA) tests, are strongly associated with recurrent thrombosis and recurrent fetal loss, i.e. the
Autor:
N, Goel, T L, Ortel, D, Bali, J P, Anderson, I S, Gourley, H, Smith, C A, Morris, M, DeSimone, D W, Branch, P, Ford, D, Berdeaux, R A, Roubey, D D, Kostyu, S F, Kingsmore, T, Thiel, C, Amos, M F, Seldin
Publikováno v:
Arthritis and rheumatism. 42(2)
To develop diagnostic criteria for a familial form of antiphospholipid antibody syndrome (APS), identify families with1 affected member, examine possible modes of inheritance, and determine linkage to potential candidate genes.Family members of proba
Publikováno v:
Thrombosis and haemostasis. 80(4)
The plasma protein beta2-glycoprotein I (beta2-GPI) is a major target of autoantibodies in patients with the antiphospholipid syndrome. To understand the physiological function of beta2-GPI and its potential role in the pathophysiology of the antipho
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(2)
"Anticardiolipin" autoantibodies (aCL) bind to anionic phospholipids only in the presence of beta 2-glycoprotein I (beta 2GPI), a phospholipid-binding plasma protein. The exact role of beta 2GPI in the antigenic specificity of these autoantibodies is