Výsledky vyhledávání - "R A McIlhinney"

The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum

Autor: A, Becher, J H, White, R A, McIlhinney

Publikováno v: Journal of neurochemistry. 79(4)

Recent evidence suggests that specialized microdomains, called lipid rafts, exist within plasma membranes. These domains are enriched in cholesterol and sphingolipids and are resistant to non-ionic detergent-extraction at 4 degrees C. They contain sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce0bd156c3863c8ea10c0828f1e63c24
https://pubmed.ncbi.nlm.nih.gov/11723171

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Metabotropic glutamate receptor type 1alpha and tubulin assemble into dynamic interacting complexes

Autor: F, Ciruela, R A, McIlhinney

Publikováno v: Journal of neurochemistry. 76(3)

Metabotropic glutamate receptors (mGlu receptors) are coupled to G-protein second messenger pathways and modulate glutamate neurotransmission in the brain, where they are targeted to specific synaptic locations. Very recently, we identified tubulin a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a1d41f192c068d0a673351994699750
https://pubmed.ncbi.nlm.nih.gov/11158246

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Mouse brain and muscle tissues constitutively express high levels of Homer proteins

Autor: M M, Soloviev, F, Ciruela, W Y, Chan, R A, McIlhinney

Publikováno v: European journal of biochemistry. 267(3)

In order to characterize expression of Homers in mouse brain and peripheral tissues we have developed a coupled reverse transcription (RT)-PCR/restriction digestion approach. This has allowed us to determine the molecular composition and relative lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bfcdfe158d3559fbe65004496d95ed9a
https://pubmed.ncbi.nlm.nih.gov/10651798

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Identification, cloning and analysis of expression of a new alternatively spliced form of the metabotropic glutamate receptor mGluR1 mRNA1

Autor: M M, Soloviev, F, Ciruela, W Y, Chan, R A, McIlhinney

Publikováno v: Biochimica et biophysica acta. 1446(1-2)

We have applied quantitative RT-PCR analysis to characterise relative levels of expression of the alternatively spliced mGluR1 mRNAs. This has also allowed us to identify and clone a new alternatively spliced form of the mGluR1 mRNA. The newly identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7eebac3f51dbcbc4f0e4003953f57353
https://pubmed.ncbi.nlm.nih.gov/10395931

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Interactions of the C terminus of metabotropic glutamate receptor type 1alpha with rat brain proteins: evidence for a direct interaction with tubulin

Autor: F, Ciruela, M J, Robbins, A C, Willis, R A, McIlhinney

Publikováno v: Journal of neurochemistry. 72(1)

Metabotropic glutamate receptors (mGluRs) are coupled to G protein second messenger pathways and modulate glutamate neurotransmission in the brain, where they are targeted to specific synaptic locations. As part of a strategy for defining the mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93f559b40d0ac1f9668a1197ae93c977
https://pubmed.ncbi.nlm.nih.gov/9886087

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Membrane targeting via protein N-myristoylation

Autor: R A, McIlhinney

Publikováno v: Methods in molecular biology (Clifton, N.J.). 88

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8817fdeb319407e9053c6baedeae443
https://pubmed.ncbi.nlm.nih.gov/9664308

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Immunochemical characterization of human N-myristoyltransferase: evidence for more than one form of the enzyme

Autor: K, Young, M, Egerton, R, Camble, A, White, R A, McIlhinney

Publikováno v: Biochemical Society transactions. 25(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e50815ecda35e66f7c10fdf264db608
https://pubmed.ncbi.nlm.nih.gov/9450059

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The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

Autor: A, Baude, Z, Nusser, J D, Roberts, E, Mulvihill, R A, McIlhinney, P, Somogyi

Publikováno v: Neuron. 11(4)

An antiserum to mGluR1 alpha labeled a 160 kd protein in immunoblots of membranes derived from rat brain or cells transfected with mGluR1 alpha. Immunoreactivity for mGluR1 alpha was present in discrete subpopulations of neurons. The GABAergic neuron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3dc5bf24378af5753fced917b0fb617a
https://pubmed.ncbi.nlm.nih.gov/8104433

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Myristoylation of flagellar creatine kinase in the sperm phosphocreatine shuttle is linked to its membrane association properties

Autor: A F, Quest, J K, Chadwick, D D, Wothe, R A, McIlhinney, B M, Shapiro

Publikováno v: The Journal of biological chemistry. 267(21)

TCK, the flagellar creatine kinase (ATP:creatine N-phosphotransferase) of sperm from the sea urchin Strongylocentrotus purpuratus is a membrane-associated lipophilic protein involved in energy transport. The cDNA derived protein sequence contains a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c2a780e8695bcfd63870e8c20073388
https://pubmed.ncbi.nlm.nih.gov/1634544

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