Zobrazeno 1 - 10
of 84
pro vyhledávání: '"R A Kloner"'
Autor:
R A, Kloner, R B, Jennings
Publikováno v:
Circulation. 104:3158-3167
In experimental studies in the dog, total proximal coronary artery occlusions of up to 15 minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 minutes of ischemia, however, induce numerous changes in the myocardi
Autor:
R. A. Kloner, A. Jacobson
Publikováno v:
MD Conference Express. 9:8-10
Autor:
J P Jarow, R A Kloner
Publikováno v:
The American Journal of Cardiology. 83:576-582
Since the release of sildenafil citrate (Viagra), increasing numbers of patients are seeking treatment for erectile dysfunction (ED). Many of the risk factors for ED are the same as those for cardiac disease. Sildenafil citrate is a highly effective
Autor:
R. A. Kloner, Yuwei Li
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 268:H426-H431
Protein kinase C (PKC) has been implicated in the cardioprotective effects of ischemic preconditioning in rabbits, but whether it plays a role in rats is unknown. We tested this preconditioning PKC theory by assessing whether the inhibition of PKC wi
Publikováno v:
Circulation. 88:659-672
BACKGROUND "Preconditioning" with brief episodes of coronary artery occlusion reduces infarct size caused by subsequent sustained ischemia. However, the effects of preconditioning on the coronary vasculature are poorly understood. We sought to determ
Autor:
S H, Rezkalla, R A, Kloner
Publikováno v:
Panminerva medica. 47(2)
Brief episodes of ischemia prior to coronary occlusion protect the heart during sustained coronary ischemia and is known as ischemic preconditioning. During acute myocardial infarction it is associated with smaller infarction size, less cardiac arrhy
Autor:
K. Przyklenk, R. A. Kloner
Publikováno v:
Basic Research in Cardiology. 91:41-43
Publikováno v:
Heart disease (Hagerstown, Md.). 1(3)
Myocardial hibernation is defined as a state of chronically reduced contractility in response to a reduction in blood supply and the ability to recover function after revascularization. There is controversy about the chronicity of a reduction in myoc
Publikováno v:
Cardiovascular drugs and therapy. 14(6)
Adenosine A1 receptor agonists given prior to myocardial ischemia limit ischemic injury in several species. However, the ability of adenosine receptor agonists to limit infarct size when given at reperfusion has proved controversial. We designed a th
Autor:
R A, Kloner, M, Weinberger, J L, Pool, S G, Chrysant, R, Prasad, S M, Harris, T M, Zyczynski, N K, Leidy, E L, Michelson
Publikováno v:
The American journal of cardiology. 87(6)
The comparative antihypertensive efficacy and tolerability of the angiotensin II receptor blocker candesartan cilexetil and the calcium channel blocker amlodipine were evaluated in an 8-week, multicenter, double-blind, randomized, parallel-group, for