Zobrazeno 1 - 10
of 74
pro vyhledávání: '"R A, de Zeeuw"'
A Fluorescent Receptor Assay for Benzodiazepines Using Coumarin-Labeled Desethylflumazenil as Ligand
Publikováno v:
Analytical Chemistry. 73:3168-3173
This article describes a novel nonisotopic receptor assay for benzodiazepines with fluorescence detection, As labeled ljgand (coumarin-labeled desethylflumazenil, CLDEF), a metabolite of the benzodiazepine antagonist flumazenil (desetheylflumazenil,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee1c41d3e36b4af485aa8ee367cfb18
https://doi.org/10.1021/ac001480f
https://doi.org/10.1021/ac001480f
Autor:
K, Ensing, R A, de Zeeuw
Publikováno v:
Pharmaceutical research. 3(6)
A number of corresponding tertiary and quaternary anticholinergic analogues were examined for their ability to inhibit specific (3)H-dexetimide binding to calf brain muscarinic receptors. In all cases the tertiary antagonists (except pirenzepine) sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::819478ea3a8efcae898cc2c66a4dd895
https://pubmed.ncbi.nlm.nih.gov/24271831
https://pubmed.ncbi.nlm.nih.gov/24271831
Publikováno v:
Preparative Biochemistry. 25:197-221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a3d9118f77be0065dc6c89ff577660
https://doi.org/10.1080/10826069508010121
https://doi.org/10.1080/10826069508010121
Autor:
K. de Jonge, R. A. de Zeeuw, A. P. Bruins, A. B. L. Lanting, K Ensing, B. F. H. Drenth, Dirk K. F. Meijer
Publikováno v:
Biological Mass Spectrometry. 22:226-234
To gather more information on stereochemical factors in the hepatic disposition of organic cations, mass spectrometry coupled to liquid chromatography was used to determine the identity of the metabolites excreted in bile after isolated rat liver per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d0c6e185ea6043c3634f036f4ea18b
https://doi.org/10.1002/bms.1200220403
https://doi.org/10.1002/bms.1200220403
Publikováno v:
Xenobiotica. 20:515-524
1. The disposition and metabolic profiling of 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin(I), a dopamine agonist, were studied in anaesthetized rats after i.v. administration and in non-anaesthetized rats after i.v. and oral dosing. No major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a98539c373d81db9a401e10796c53a
https://doi.org/10.3109/00498259009046866
https://doi.org/10.3109/00498259009046866
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 794(1)
Solid-phase extraction (SPE) was directly coupled to mass spectrometry (MS) to assess the feasibility of the system for the rapid determination of prednisolone in serum. A C(18) stationary phase allowed washing of the cartridge with 25% methanol. Elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb9dc051c65b607e2650e27152441b29
https://pubmed.ncbi.nlm.nih.gov/12888211
https://pubmed.ncbi.nlm.nih.gov/12888211
Publikováno v:
Rapid communications in mass spectrometry : RCM. 17(3)
Ion suppression effects were observed during the determination of clenbuterol in urine with solid-phase extraction/multiple-stage ion-trap mass spectrometry (SPE/MS(3)), despite the use of atmospheric pressure chemical ionisation. During SPE, a polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06ccd6d258e38aea1bc22c3f96031d7a
https://pubmed.ncbi.nlm.nih.gov/12539191
https://pubmed.ncbi.nlm.nih.gov/12539191
Publikováno v:
Forensic Science International, 121(1-2), 89-96
Capillary electrophoresis (CE) is a modern separation technique that has some distinct advantages for toxicological analysis, such as a high efficiency, fast analysis, flexibility, and complementary separation mechanisms to chromatographic methods. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817c8554de38d10fb9be6bad9e27bb2b
https://pubmed.ncbi.nlm.nih.gov/11516892
https://pubmed.ncbi.nlm.nih.gov/11516892
Publikováno v:
Electrophoresis. 21(15)
A review is presented on the use of charged cyclodextrins (CDs) as chiral selectors in capillary electrophoresis (CE) for the separation of analytes in pharmaceutical analysis. An overview is given of theoretical models that have been developed for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b303edc5e52fffc64053c0eb92d49f30
https://pubmed.ncbi.nlm.nih.gov/11001221
https://pubmed.ncbi.nlm.nih.gov/11001221
Publikováno v:
Electrophoresis. 21(8)
The intra- and interinstrument reproducibilities of four capillary electrophoresis instruments were studied for identification purposes in systematic toxicological analysis (STA). A test set of 20 acidic test compounds and 5 reference compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fbfc910da4b3e34c880dc9bc999f0ce
https://pubmed.ncbi.nlm.nih.gov/10832886
https://pubmed.ncbi.nlm.nih.gov/10832886