Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R A, Smulders"'
Publikováno v:
The American Journal of Emergency Medicine. 60:106-115
Chest pain is among the most common reasons for Emergency Department (ED) presentation, while most patients should be considered low risk for Acute Coronary Syndrome (ACS). Management of these patients places a significant burden on our health care s
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 43:227-238
Objective: The pharmacokinetics of solifenacin succinate (YM905; Vesicare®), a new, bladder-selective, muscarinic receptor antagonist for the treatment of overactive bladder in young/middle-aged and elderly subjects werecompared. Material: Solifenac
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 16:449-459
Paroxetine inhibits cytochrome P(450) 2D6, which is involved in the metabolism of mirtazapine. The possible drug-drug interaction between two pharmacologically distinct antidepressants, mirtazapine and paroxetine, has been investigated in a randomize
Publikováno v:
European Journal of Clinical Investigation. 30:853-860
Background The usefulness of treatment with an angiotensin-converting enzyme-inhibitor (ACE-inhibitor) in normotensive patients with type 1 diabetes is controversial. We investigated whether ACE-inhibition improves endothelial function in such patien
Autor:
R A, Smulders, W, Zhang, S A, Veltkamp, J, van Dijk, W J J, Krauwinkel, J, Keirns, T, Kadokura
Publikováno v:
Diabetes, obesitymetabolism. 14(10)
To investigate the effect of ipragliflozin on the pharmacokinetics of sitagliptin, pioglitazone or glimepiride and vice versa in healthy subjects.Three trials with an open-label, randomized, two-way crossover design were conducted in healthy subjects
Publikováno v:
European journal of clinical investigation. 30(10)
The usefulness of treatment with an angiotensin-converting enzyme-inhibitor (ACE-inhibitor) in normotensive patients with type 1 diabetes is controversial. We investigated whether ACE-inhibition improves endothelial function in such patients and comp
Publikováno v:
Molecular biology reports. 25(4)
alphaA-Crystallin is a member of the small heat shock protein family that is abundantly expressed as a structural component in the vertebrate eye lens. In lenses of rodents and some other mammals, there occurs a minor variant of alphaA-crystallin, wh
Autor:
R A, Smulders, C D, Stehouwer, C G, Schalkwijk, A J, Donker, V W, van Hinsbergh, J M, TeKoppele
Publikováno v:
Thrombosis and haemostasis. 80(1)
Dysfunction of the vascular endothelium is considered an early step in the development of diabetic angiopathy. Hyperglycaemia results in endothelial dysfunction, both through direct effects of glucose and through formation of advanced glycosylation e
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation, 15, 281-286. Informa Healthcare
Lambert, J, Smulders, R A, Aarsen, M, Gallay, F P & Stehouwer, C D A 1997, ' The acute effect of hyperglycaemia on vessel wall properties ', Scandinavian Journal of Clinical and Laboratory Investigation, vol. 15, pp. 281-286 . https://doi.org/10.3109/00365519709084588
Lambert, J, Smulders, R A, Aarsen, M, Gallay, F P & Stehouwer, C D A 1997, ' The acute effect of hyperglycaemia on vessel wall properties ', Scandinavian Journal of Clinical and Laboratory Investigation, vol. 15, pp. 281-286 . https://doi.org/10.3109/00365519709084588
Arterial distensibility is a marker of functional and structural vessel wall properties. A decreased distensibility is an important risk factor for cardiovascular disease. In insulin-dependent diabetes mellitus of short duration, arterial stiffness h