Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R A, Sarabdjitsingh"'
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0253406 (2022)
Early-life adversity (ELA) causes long-lasting structural and functional changes to the brain, rendering affected individuals vulnerable to the development of psychopathologies later in life. Immediate-early genes (IEGs) provide a potential marker fo
Externí odkaz:
https://doaj.org/article/10d1ab6802c8414ea115e8905db76c4d
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0249102 (2021)
Environmental information plays an important role in remembering events. Information about stable aspects of the environment (here referred to as 'context') and the event are combined by the hippocampal system and stored as context-dependent memory.
Externí odkaz:
https://doaj.org/article/6fe255eaf9bc4a169b1d482cc8f65a51
Autor:
Henk Karst, Wouter J. Droogers, Nelleke van der Weerd, Ruth Damsteegt, Nicky van Kronenburg, R. Angela Sarabdjitsingh, Marian Joëls
Publikováno v:
Neuropharmacology. 234:109543
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185061 (2017)
Adverse experiences early in life impair cognitive function both in rodents and humans. In humans this increases the vulnerability to develop mental illnesses while in the rodent brain early life stress (ELS) abnormalities are associated with changes
Externí odkaz:
https://doaj.org/article/9cd41e79917c431793bc779f1892bd31
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164551 (2016)
INTRODUCTION:Early life stress (ELS) increases the risk for developing psychopathology in adulthood. When these effects occur is largely unknown. We here studied at which time during development ELS affects hippocampal synaptic plasticity, from early
Externí odkaz:
https://doaj.org/article/c87850e060b24f82a2d4a592758d1410
Autor:
R Angela Sarabdjitsingh, Natasha Pasricha, Johanna A S Smeets, Amber Kerkhofs, Lenka Mikasova, Henk Karst, Laurent Groc, Marian Joëls
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145858 (2016)
In recent years it has become clear that corticosteroid hormones (such as corticosterone) are released in ultradian pulses as a natural consequence of pituitary-adrenal interactions. All organs, including the brain, are thus exposed to pulsatile chan
Externí odkaz:
https://doaj.org/article/c31da707038e42d78b234dbec98292f3
Autor:
Valeria Bonapersona, Heike Schuler, Ruth Damsteegt, Youri Adolfs, R. Jeroen Pasterkamp, Martijn P. van den Heuvel, Marian Joëls, R. Angela Sarabdjitsingh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2114002119. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2114002119, 1-9. National Acad Sciences
Bonapersona, V, Schuler, H, Damsteegt, R, Adolfs, Y, Pasterkamp, R J, van den Heuvel, M P, Joëls, M & Sarabdjitsingh, R A 2022, ' The mouse brain after foot shock in four dimensions : Temporal dynamics at a single-cell resolution ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 8, e2114002119 . https://doi.org/10.1073/pnas.2114002119
Bonapersona, V, Schuler, H, Damsteegt, R, Adolfs, Y, Pasterkamp, R J, van den Heuvel, M P, Joëls, M & Sarabdjitsingh, R A 2022, ' The mouse brain after foot shock in four dimensions : Temporal dynamics at a single-cell resolution ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 8, e2114002119, pp. 1-9 . https://doi.org/10.1073/pnas.2114002119
Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2114002119. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2114002119, 1-9. National Acad Sciences
Bonapersona, V, Schuler, H, Damsteegt, R, Adolfs, Y, Pasterkamp, R J, van den Heuvel, M P, Joëls, M & Sarabdjitsingh, R A 2022, ' The mouse brain after foot shock in four dimensions : Temporal dynamics at a single-cell resolution ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 8, e2114002119 . https://doi.org/10.1073/pnas.2114002119
Bonapersona, V, Schuler, H, Damsteegt, R, Adolfs, Y, Pasterkamp, R J, van den Heuvel, M P, Joëls, M & Sarabdjitsingh, R A 2022, ' The mouse brain after foot shock in four dimensions : Temporal dynamics at a single-cell resolution ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 8, e2114002119, pp. 1-9 . https://doi.org/10.1073/pnas.2114002119
Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2114002119. National Academy of Sciences
Acute stress leads to sequential activation of functional brain networks. A biologically relevant question is exactly which (single) cells belonging to brain networks are changed in activity over time after acute stress across the entire brain. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e65d275e9ee4359b28e321622ff6c31
https://research.rug.nl/en/publications/b71ed058-cd87-4586-913f-96cbf5a2fa84
https://research.rug.nl/en/publications/b71ed058-cd87-4586-913f-96cbf5a2fa84
Early life adversity (ELA) is a well-documented risk factor for psychiatric illnesses in humans. This risk may, in part, be conferred by structural changes induced by ELA, lasting into adulthood. We here review the evidence for such lasting structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4bc7fee280abfb649610920a123b7e3
https://doi.org/10.1101/2022.01.17.476580
https://doi.org/10.1101/2022.01.17.476580
While many people experience potentially threatening events during their life, only a minority develops posttraumatic stress disorder (PTSD). The identification of individuals at risk among those exposed to trauma is crucial for PTSD prevention in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c572e1bb9e7fc35c2fcd741dfbd6a93
https://doi.org/10.1101/2021.07.17.452780
https://doi.org/10.1101/2021.07.17.452780
Early-life adversity (ELA) causes long-lasting structural and functional changes to the brain, rendering affected individuals vulnerable to the development of psychopathologies later in life. Immediate-early genes (IEGs) provide a potential marker fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c16c5f8dfb327591a53a81b810cc7a
https://doi.org/10.1101/2021.06.07.447369
https://doi.org/10.1101/2021.06.07.447369