Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R A, Paégle"'
Publikováno v:
Bioorganicheskaia khimiia. 17(6)
In an effort to develop more potent inhibitors of purine nucleoside phosphorylase (PNP, EC 2.4.2.1) as immunosuppressive and anticancer chemotherapeutic agents, the affinity of the electrophoretically homogeneous enzyme from rabbit kidney for sixteen
Autor:
V. D. Grigor'eva, Igor A. Mikhailopulo, Yu. A. Maurin'sh, R. A. Paégle, O. V. Sakhartova, M. Yu. Lidak
Publikováno v:
Chemistry of Heterocyclic Compounds. 25:198-202
Condensation of the trimethylsilyl derivatives of theophyllin and 3-isobutyl-1-methylxanthine with Β-D-glucofuranourono-6,3-lactone in the presence of trimethylsilyl trifluoromethanesulfonate has given N(7)-Β-D-glucofuranouronosides. Their hydrolyt
Publikováno v:
Chemistry of Heterocyclic Compounds. 8:644-648
The protolysis constants of β-(1-uracilyl)propionitriles and β-(1-uracilyl)propionic α-amino-β-(1-pyrimidyl)propionic, and α-amino-γ-(1-pyrimidyl)butyric acids (willardiine analogs) were determined. The electronic effect of substituents and of
Publikováno v:
Chemistry of Heterocyclic Compounds. 7:237-239
Synthetic routes to and the properties of N-(2-chloro-5-fluoro-4-pyrimidyl)- and N-(2-ethylthio-5-fluoro-4-pyrimidyl)-substituted amino acids are shown.
Publikováno v:
Chemistry of Heterocyclic Compounds. 8:641-643
The activated ether and dicyclohexylcarbodiimide methods were used to obtain di- and tripeptides of β-(1-thyminyl)-α-alanine and β-(9-adenyl)-α-alanine.
Publikováno v:
Chemistry of Heterocyclic Compounds. 6:934-935
One of the types of pyurinylpeptides (i.e., peptides constructed of pyrimidyl-and purinyl-α-amino acids) consists of peptides including residues of only those α-amino acids the lateral radicals of which contain nucleic bases. Below, such amino acid