Zobrazeno 1 - 10
of 15
pro vyhledávání: '"R A, Ophoff"'
Publikováno v:
Human Molecular Genetics. 10:545-551
Recent interest in using association studies to investigate complex traits has focused attention on understanding linkage disequilibrium (LD) in the human genome. We examined the genome-wide distribution and magnitude of such background LD (BLD) usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c71c90622e0fe38a58a5e2e7e22e504
https://doi.org/10.1093/hmg/10.5.545
https://doi.org/10.1093/hmg/10.5.545
Autor:
C D, Schubart, M P M, Boks, E J, Breetvelt, W A, van Gastel, R H H, Groenwold, R A, Ophoff, I E C, Sommer, R S, Kahn
Publikováno v:
Acta psychiatrica Scandinavica. 123(5)
To investigate the relationship between cannabis use and mental health.A cross-sectional analysis in a sample of 17 698 individuals with a mean age of 22 years (SD: 4.2). Participants provided information on the amount and initial age of cannabis use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc6f60dca1b2dab057241e23e21be960
https://pubmed.ncbi.nlm.nih.gov/21198455
https://pubmed.ncbi.nlm.nih.gov/21198455
Publikováno v:
European journal of human genetics : EJHG. 6(4)
Clinical and genetic heterogeneity as well as influence of environmental factors have hampered identification of the genetic factors which are involved in episodic diseases such as migraine, episodic ataxia and epilepsy. The study of rare, but clearl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b143925397dfea6191bf08190aa598e6
https://pubmed.ncbi.nlm.nih.gov/9781035
https://pubmed.ncbi.nlm.nih.gov/9781035
Publikováno v:
Histology and histopathology. 13(3)
Neurotransmitter release, neuronal excitation, and a whole variety of other neuronal functions are controlled by the intra/extra cellular Ca2+ gradient. The major pathway for entry of Ca2+ into the excitable cells is mediated by voltage-gated Ca2+ ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e0a6f0886d76419fac3f4038f32014e
https://pubmed.ncbi.nlm.nih.gov/9690139
https://pubmed.ncbi.nlm.nih.gov/9690139
Autor:
A, Maassen VanDenBrink, M N, Vergouwe, R A, Ophoff, S L, Naylor, H G, Dauwerse, P R, Saxena, M D, Ferrari, R R, Frants
Publikováno v:
American journal of medical genetics. 77(5)
The 5-HT1F receptor, which is present in both human vascular and neuronal tissue, may mediate the therapeutic effect and/or side-effects of sumatriptan. We investigated the chromosomal localization of the 5-HT1F receptor gene and the relation between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b9085adb66a42a4db3efc13cc0ff9b1
https://pubmed.ncbi.nlm.nih.gov/9632173
https://pubmed.ncbi.nlm.nih.gov/9632173
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 142(18)
There is increasing evidence of involvement of genes coding for ion channels in the pathogenesis of paroxysmal neurological disorders. Recently for instance, mutations in the calcium channel gene on chromosome 19 were identified in migraine, ataxia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d14bbe8c30d9e4b73a2af7d5cee1aa8f
https://pubmed.ncbi.nlm.nih.gov/9623202
https://pubmed.ncbi.nlm.nih.gov/9623202
Publikováno v:
Neurology. 50(4)
Familial hemiplegic migraine (FHM) is an autosomal dominant subtype of migraine with aura, with half of the families being assigned to chromosome 19p13. We identified missense mutations in a brain-specific calcium channel alpha1A-subunit (CACNA1A) ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79f693425447220f3945ed234c214cf3
https://pubmed.ncbi.nlm.nih.gov/9566402
https://pubmed.ncbi.nlm.nih.gov/9566402
Publikováno v:
Neurologia (Barcelona, Spain). 12
A gene for familial hemiplegic migraine (FHM), a subtype of migraine with aura, has been assigned to chromosome 19p13. In this region we identified a brain-specific P/Q-type calcium channel alpha 1A-subunit gene, CACNL1A4, with 47 exons covering 300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dac60dd82593de1ec36102448e341e7
https://pubmed.ncbi.nlm.nih.gov/9436352
https://pubmed.ncbi.nlm.nih.gov/9436352
Publikováno v:
Headache. 37(8)
A gene for familial hemiplegic migraine, a subtype of migraine with aura, was assigned to chromosome 19p13. In this region, we identified a brain-specific P/Q-type calcium-channel alpha 1A-subunit gene, CACNA 1A, with 47 exons covering 300 kb. Sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e43ec1563761c263cce03531cc76e3bf
https://pubmed.ncbi.nlm.nih.gov/9329229
https://pubmed.ncbi.nlm.nih.gov/9329229
Autor:
R A, Ophoff, G M, Terwindt, M N, Vergouwe, R, van Eijk, H, Mohrenweiser, M, Litt, M H, Hofker, J, Haan, M D, Ferrari, R R, Frants
Publikováno v:
European journal of human genetics : EJHG. 4(6)
Familial hemiplegic migraine (FHM) is an autosomal domianant subtype of migraine with attacks, associated with transient episodes of hemiparesis. One of the genes for FHM has been assigned to chromosome 19p13. Detailed analysis of critical recombinan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6dff0fcb73ccbe1bb9cde2ee49624d1
https://pubmed.ncbi.nlm.nih.gov/9043864
https://pubmed.ncbi.nlm.nih.gov/9043864