Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R A, Nemenoff"'
Autor:
M, Niederberger, P, Ginès, P Y, Martin, J, St John, P, Woytaszek, L, Xu, P, Tsai, R A, Nemenoff, R W, Schrier
Publikováno v:
Hepatology (Baltimore, Md.). 27(1)
Indirect evidence suggests that the renal and vascular production of prostaglandins is increased in cirrhosis with ascites. However, the activity of the enzymes regulating the prostaglandin pathway has not been investigated in cirrhosis. The aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::991941641eda65d48b2670ce9b592734
https://pubmed.ncbi.nlm.nih.gov/9425915
https://pubmed.ncbi.nlm.nih.gov/9425915
Autor:
P, Ginès, X, Li, J L, Zamarripa, S E, Brown, E D, Wieder, T, Nakamura, P S, Guzelian, R W, Schrier, L E, Heasley, R A, Nemenoff
Publikováno v:
Hepatology (Baltimore, Md.). 22(4 Pt 1)
The response of rat hepatocytes to hormones and growth factors has been extensively studied with respect to phospholipase regulation and calcium mobilization. However, the mitogen-activated protein (MAP) kinase cascade which integrates signals from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b270d3c274a8448a480040eb1e37c927
https://pubmed.ncbi.nlm.nih.gov/7557884
https://pubmed.ncbi.nlm.nih.gov/7557884
Publikováno v:
Zhonghua yi xue za zhi. 75(4)
Activation of the mitogen-activated protein kinase (MAPK) pathway is believed to play a critical role in normal and pathophysiologic proliferation of mesangial cells. Recent studies have shown that MAP kinase activation by growth factors in other cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fa6fba85aa4014f5d70118b00ad0738
https://pubmed.ncbi.nlm.nih.gov/7788549
https://pubmed.ncbi.nlm.nih.gov/7788549
Publikováno v:
The Journal of biological chemistry. 269(30)
Vascular smooth muscle cells have been shown to exist in two phenotypic states which have been designated proliferative and contractile. The properties of rat aortic vascular smooth muscle cells grown on Matrigel were compared with cells grown on unt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5087a53a0df8724951bb67bf6c147661
https://pubmed.ncbi.nlm.nih.gov/8034734
https://pubmed.ncbi.nlm.nih.gov/8034734
Publikováno v:
The Journal of biological chemistry. 269(3)
The 85-kDa cytoplasmic phospholipase A2 (cPLA2) is the major hormone and growth factor-regulated enzyme that catalyzes release of arachidonic acid in mammalian cells. Activation of cPLA2 requires elevation of intracellular Ca2+ and the phosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a58ad56917186906d572ec37cca8a59b
https://pubmed.ncbi.nlm.nih.gov/8294438
https://pubmed.ncbi.nlm.nih.gov/8294438
Publikováno v:
The Journal of biological chemistry. 268(3)
Phospholipase A2 (PLA2) is the enzyme regulating the release of arachidonic acid in most cell types. A high molecular mass, 85-kDa soluble form of PLA2 (cPLA2) has recently been identified, the activity of which is stably increased by stimulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d34102fe225b5dd954efe142a0350871
https://pubmed.ncbi.nlm.nih.gov/8380583
https://pubmed.ncbi.nlm.nih.gov/8380583
Publikováno v:
The Journal of biological chemistry. 265(9)
We have previously characterized a hormonally regulated soluble form of phospholipase A2 (PLA2) in the cultured renal mesangial cell which is similar and possibly identical to the major form in rat kidney. In an attempt to further characterize the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fdca55a26382364bfa9a658f087b850
https://pubmed.ncbi.nlm.nih.gov/2108162
https://pubmed.ncbi.nlm.nih.gov/2108162
Publikováno v:
The Journal of biological chemistry. 257(24)
Addition of insulin to Triton-solubilized extracts of human placental membranes selectively stimulates the incorporation of 32P from [gamma-32P]ATP into an endogenous 95,000-dalton protein, which is identified as a component of the insulin receptor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1825b3450f4b1afa70995850fe850961
https://pubmed.ncbi.nlm.nih.gov/6757253
https://pubmed.ncbi.nlm.nih.gov/6757253
Publikováno v:
The Journal of biological chemistry. 255(22)
Insulin stimulated the uptake of 86Rb+ (a K+ analog) in rat adipocytes and increased the steady state concentration of intracellular potassium. Half-maximal stimulation occurred at an insulin concentration of 200 pM. Both basal- and insulin-stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc0c362a01f73e4d33a2fd8263d127c1
https://pubmed.ncbi.nlm.nih.gov/6253493
https://pubmed.ncbi.nlm.nih.gov/6253493
Publikováno v:
The Journal of biological chemistry. 263(32)
The activity of phospholipase A2 (PLA2), the regulatory enzyme in arachidonic acid release and prostaglandin synthesis, was measured in cell-free extracts of rat renal mesangial cells. Arginine vasopressin (AVP) and phorbol myristate acetate (PMA) bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a31269c76f8ccc0fb4a1e06f69bea8d8
https://pubmed.ncbi.nlm.nih.gov/3141409
https://pubmed.ncbi.nlm.nih.gov/3141409