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Akademický článek

Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound

Autor: Pia H Puhakka, Nikae C R te Moller, Petri Tanska, Simo Saarakkala, Virpi Tiitu, Rami K Korhonen, Harold Brommer, Tuomas Virén, Jukka S Jurvelin, Juha Töyräs

Publikováno v: Acta Orthopaedica, Vol 87, Iss 4, Pp 418-424 (2016)

Background and purpose — Arthroscopic estimation of articular cartilage thickness is important for scoring of lesion severity, and measurement of cartilage speed of sound (SOS)—a sensitive index of changes in cartilage composition. We investigate

Externí odkaz: https://doaj.org/article/ef09579f60a0457cb983b73e9a082adc

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Dual‐contrast computed tomography enables detection of equine posttraumatic osteoarthritis in vitro

Autor: Jaakko K. Sarin, Olli Nykänen, P. René van Weeren, Irina A. D. Mancini, Mikko J. Nissi, Nikae C. R. te Moller, Jos Malda, Harold Brommer, Juha Töyräs, Jetze Visser, Annina E. A. Saukko, Harrie Weinans, Mark W. Grinstaff

Publikováno v: Journal of Orthopaedic Research: a journal for musculoskeletal investigation, 40(3)
Journal of Orthopaedic Research, 40, 703-711
Journal of Orthopaedic Research, 40, 3, pp. 703-711

Contains fulltext : 251100.pdf (Publisher’s version ) (Open Access) To prevent the progression of posttraumatic osteoarthritis, assessment of cartilage composition is critical for effective treatment planning. Posttraumatic changes include proteogl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d00ac99f3b61cb93e7e6ab50a901c96
https://doi.org/10.1002/jor.25066

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Evaluation of articular cartilage with quantitative MRI in an equine model of post‐traumatic osteoarthritis

Autor: Abdul Wahed Kajabi, P. René van Weeren, Irina A. D. Mancini, Olli Nykänen, Nikae C. R. te Moller, Miika T. Nieminen, Jetze Visser, Mikko J. Nissi, Harold Brommer, Victor Casula, Jos Malda, Juuso H. Ketola, Jaakko K. Sarin, Juha Töyräs

Publikováno v: Journal of Orthopaedic Research
Journal of Orthopaedic Research, 39, 63-73
Journal of Orthopaedic Research, 39, 1, pp. 63-73

Contains fulltext : 245050.pdf (Publisher’s version ) (Open Access) Chondral lesions lead to degenerative changes in the surrounding cartilage tissue, increasing the risk of developing post-traumatic osteoarthritis (PTOA). This study aimed to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fc2fcb9c8b8919facf58229cc3d057
https://doi.org/10.1002/jor.24780

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T2* mapping in an equine articular groove model: Visualizing changes in collagen orientation

Autor: Martijn Froeling, Keita Ito, Dennis W. J. Klomp, Harold Brommer, Sander Brinkhof, Nikae C. R. te Moller, René van Weeren

Publikováno v: Journal of Orthopaedic Research

T2* mapping is promising for the evaluation of articular cartilage collagen. In this work, a groove model in a large animal is used as a model for posttraumatic arthritis. We hypothesized that T2* mapping could be employed to differentiate between he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2810be39aff660eb9001c0466ec45a8
https://doi.org/10.1002/jor.24764

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Site- and Zone-Dependent Changes in Proteoglycan Content and Biomechanical Properties of Bluntly and Sharply Grooved Equine Articular Cartilage

Autor: Ali, Mohammadi, Nikae C R, Te Moller, Mohammadhossein, Ebrahimi, Saskia, Plomp, Harold, Brommer, P René, van Weeren, Janne T A, Mäkelä, Juha, Töyräs, Rami K, Korhonen

Publikováno v: Annals of biomedical engineering. 50(12)

In this study, we mapped and quantified changes of proteoglycan (PG) content and biomechanical properties in articular cartilage in which either blunt or sharp grooves had been made, both close to the groove and more remote of it, and at the opposing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1919916622f3c5faeb69e11cddd51e9
https://pubmed.ncbi.nlm.nih.gov/35754073

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T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage

Autor: O, Nykänen, J K, Sarin, J H, Ketola, H, Leskinen, N C R, Te Moller, V, Tiitu, I A D, Mancini, J, Visser, H, Brommer, P R, van Weeren, J, Malda, J, Töyräs, M J, Nissi

Publikováno v: Osteoarthritis and cartilage. 27(10)

To investigate the potential of quantitative susceptibility mapping (QSM) and T2* relaxation time mapping to determine mechanical and structural properties of articular cartilage via univariate and multivariate analysis.Samples were obtained from a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d413d33aa740912f034ec1c47c38d446
https://pubmed.ncbi.nlm.nih.gov/31276818

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Spectroscopic Evaluation of Post-Traumatic Osteoarthritis in Shetland Ponies

Autor: Isaac O. Afara, Irina A. D. Mancini, Jos Malda, René van Weeren, Jaakko K. Sarin, Nikae C. R. te Moller, Juha Töyräs, Harold Brommer

Publikováno v: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS).

We present preliminary findings on multivariate modeling between cartilage biomechanical properties and spectroscopic measurements, performed in arthroscopic surgery and laboratory. Also, generic multivariate regression techniques were compared.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6405fb2e41af89d0c837809600a7006
https://doi.org/10.1364/ots.2018.otu4d.5

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