Zobrazeno 1 - 10
of 1 390
pro vyhledávání: '"R A, Johnston"'
Autor:
Matthew P. Goetz, Irfan Cicin, Laura Testa, Sara M. Tolaney, Jens Huober, Valentina Guarneri, Stephen R. D. Johnston, Miguel Martin, Priya Rastogi, Nadia Harbeck, Ashwin Shahir, Ran Wei, Valérie André, Hope S. Rugo, Joyce O’Shaughnessy
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract In monarchE, adjuvant abemaciclib significantly improved invasive disease-free survival (IDFS) and distant relapse-free survival (DRFS), with sustained benefit beyond the 2-year treatment period. Abemaciclib dose reductions were allowed to p
Externí odkaz:
https://doaj.org/article/1378a75d34cd4a89ad1255e30c08bb59
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-19 (2023)
Abstract The human epidermal growth factor receptor 2 (HER2) is overexpressed in 13–22% of breast cancers (BC). Approximately 60–70% of HER2+ BC co-express hormone receptors (HRs). HR/HER2 co-expression modulates response to both anti-HER2–dire
Externí odkaz:
https://doaj.org/article/680e57aefd68447cbc25c5d6d3fb71ce
Autor:
Shani Paluch-Shimon, Patrick Neven, Jens Huober, Irfan Cicin, Matthew P. Goetz, Chikako Shimizu, Chiun-Sheng Huang, Hans Joachim Lueck, Jane Beith, Eriko Tokunaga, Jessica Reyes Contreras, Rosane Oliveira de Sant’Ana, Ran Wei, Ashwin Shahir, Sarah C. Nabinger, Tammy Forrester, Stephen R. D. Johnston, Nadia Harbeck
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Abemaciclib is the first and only cyclin-dependent kinases 4 and 6 inhibitor approved for adjuvant treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−), node-positive, and high-risk ear
Externí odkaz:
https://doaj.org/article/9dbf86693a4a460dbf6601907c6ba0ed
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background and aims: Atherosclerotic plaque rupture in the carotid artery can cause small emboli to travel to cerebral arteries, causing blockages and preventing blood flow leading to stroke. Contrast enhanced micro computed tomography (CEμCT) using
Externí odkaz:
https://doaj.org/article/4d77b9009b914ed8a1cb2c89bfedf9b2
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
A critical decline of functional insulin-producing pancreatic β-cells is the central pathologic element of both type 1 and type 2 diabetes. Mammalian Sterile 20-like kinase 1 (MST1) is a key mediator of β-cell failure and the identification of nera
Externí odkaz:
https://doaj.org/article/0c9dd3492760421480a43eb22fe8b545
Autor:
Stephen R. D. Johnston
Publikováno v:
Annals of Palliative Medicine. 12:421-426
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474e18f19df74af32188f6525b7d7327
https://doi.org/10.21037/apm-22-981
https://doi.org/10.21037/apm-22-981
Autor:
Stephen R D, Johnston
Publikováno v:
Hematology/Oncology Clinics of North America. 37:89-102
There is now a deeper understanding of the biology of hormone receptor-positive (HR+) early breast cancer (EBC) that can be used to inform assessment of risk and prognosis, and also guide more effective adjuvant systemic therapies. For postmenopausal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bd8e4378d29fc6f48e0b56673dc4ad
https://doi.org/10.1016/j.hoc.2022.08.011
https://doi.org/10.1016/j.hoc.2022.08.011
Autor:
Stephen R D, Johnston, Masakazu, Toi, Joyce, O'Shaughnessy, Priya, Rastogi, Mario, Campone, Patrick, Neven, Chiun-Sheng, Huang, Jens, Huober, Georgina Garnica, Jaliffe, Irfan, Cicin, Sara M, Tolaney, Matthew P, Goetz, Hope S, Rugo, Elzbieta, Senkus, Laura, Testa, Lucia, Del Mastro, Chikako, Shimizu, Ran, Wei, Ashwin, Shahir, Maria, Munoz, Belen, San Antonio, Valérie, André, Nadia, Harbeck, Miguel, Martin
Publikováno v:
The Lancet Oncology. 24:77-90
Adjuvant abemaciclib plus endocrine therapy previously showed a significant improvement in invasive disease-free survival and distant relapse-free survival in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2; also known as ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff773b443545dc60195d174427ba206
https://doi.org/10.1016/s1470-2045(22)00694-5
https://doi.org/10.1016/s1470-2045(22)00694-5
Autor:
Basrull N. Bhaludin, Nina Tunariu, Dow-Mu Koh, Christina Messiou, Alicia F. Okines, Sophie E. McGrath, Alistair E. Ring, Marina M. Parton, Bhupinder Sharma, Tanja Gagliardi, Steven D. Allen, Romney Pope, Stephen R. D. Johnston, Kate Downey
Publikováno v:
European Radiology. 32:6514-6525
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a7da00a1116c70dd3b1a506399b7be0
https://doi.org/10.1007/s00330-022-08714-6
https://doi.org/10.1007/s00330-022-08714-6
