Zobrazeno 1 - 3
of 3
pro vyhledávání: '"R A, Humerickhouse"'
Autor:
R A, Humerickhouse, M E, Dolan, D J, Haraf, B, Brockstein, K, Stenson, M, Kies, L, Sulzen, M J, Ratain, E E, Vokes
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(2)
5-Fluorouracil (5-FU) is an effective enhancer of radiation therapy (RT) in head and neck cancers. Due to rapid, predominantly hepatic metabolism by dihydropyrimidine dehydrogenase (DPD) and suggested clinical benefit from prolonged drug exposure, 5-
Autor:
R A, Humerickhouse, K R, Bidasee, K, Gerzon, J T, Emmick, S, Kwon, J L, Sutko, L, Ruest, H R, Besch
Publikováno v:
The Journal of biological chemistry. 269(48)
The plant alkaloids ryanodine and dehydroryanodine are specific and potent modulators of the sarcoplasmic reticulum calcium release channel. In the present study, acidic, basic, and neutral side chains esters of these diterpene compounds were prepare
Publikováno v:
Molecular pharmacology. 44(2)
Two novel natural ryanoids from extracts of the wood of Ryania speciosa Vahl were evaluated with sarcoplasmic reticulum (SR) vesicles for their binding affinities and their activating and deactivating effects on Ca2+ release channels. The new ryanoid