Zobrazeno 1 - 10
of 11
pro vyhledávání: '"R A, Coulombe"'
Autor:
A Henning, Jana E. Compton, B Hatteberg, R A Coulombe, L Erban, J. R. Brooks, J E Selker, S L Pearlstein
Publikováno v:
Nutr Cycl Agroecosyst
Nitrate leaching is an important yet difficult to manage contribution to groundwater and surface water contamination in agricultural areas. We examine 14 farm fields over a four year period (2014–2017) in the southern Willamette Valley, providing 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b3e29172d61385e6c6f27f6afbcc7c
https://europepmc.org/articles/PMC8318121/
https://europepmc.org/articles/PMC8318121/
Publikováno v:
Cytogenetic and genome research. 125(1)
Cytochromes P450 (P450 for protein; CYP for gene) are a superfamily of membrane-bound hemoproteins that oxidize a large number of endogenous and exogenous compounds. Through oxidation reactions, these enzymes are often responsible for the toxic and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fba408bc12f1a92a12f2499478f1e89c
https://pubmed.ncbi.nlm.nih.gov/19617698
https://pubmed.ncbi.nlm.nih.gov/19617698
Publikováno v:
Cytogenetic and genome research. 116(1-2)
Cytochromes P450 (P450) are a superfamily of membrane-bound hemoproteins that oxidize a large number of endogenous and exogenous compounds. The recently cloned P450 gene (CYP1A5) encodes the primary protein responsible for epoxidation of aflatoxin B(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c211eaba2f287f5c723661eb71d66e95
https://pubmed.ncbi.nlm.nih.gov/17268186
https://pubmed.ncbi.nlm.nih.gov/17268186
Autor:
B L, Stegelmeier, J A, Edgar, S M, Colegate, D R, Gardner, T K, Schoch, R A, Coulombe, R J, Molyneux
Publikováno v:
Journal of natural toxins. 8(1)
More than 350 PAs have been identified in over 6,000 plants in the Boraginaceae, Compositae, and Leguminosae families (Table 1). About half of the identified PAs are toxic and several have been shown to be carcinogenic in rodents. PA-containing plant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8a2788149cb5698c54b445edf52837f
https://pubmed.ncbi.nlm.nih.gov/10091131
https://pubmed.ncbi.nlm.nih.gov/10091131
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(4)
The pharmacokinetics of carbocyclic 3-deazaadenosine (Cc3Ado), a competitive inhibitor of S-adenosyl-L-homocysteine hydrolase and novel antiviral agent, was investigated in female BALB/c mice. Mice were dosed either orally or intravenously with a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49cda7ccd385d7956ce425ea9e2bf8df
https://pubmed.ncbi.nlm.nih.gov/8104112
https://pubmed.ncbi.nlm.nih.gov/8104112
Publikováno v:
Cancer research. 50(16)
Aflatoxin B1 (AFB1) DNA binding, adduct formation, and AFB1-DNA adduct repair were studied in tracheal explants from rabbit, hamster, and rat. These species vary in populations of cytochrome P-450-containing nonciliated tracheal epithelial cells. Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc476fc592bb92d23a2b0175e365e570
https://pubmed.ncbi.nlm.nih.gov/2116221
https://pubmed.ncbi.nlm.nih.gov/2116221
Publikováno v:
Cancer research. 50(8)
Aflatoxin B1 (AFB1) is thought to be an occupational risk factor for airway carcinogenesis where exposure to AFB1-laden grain dusts is common. Since activation of AFB1 is catalyzed by cytochromes P-450 associated with the smooth endoplasmic reticulum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2658377fd2d52083a58ce5fa51128844
https://pubmed.ncbi.nlm.nih.gov/2107974
https://pubmed.ncbi.nlm.nih.gov/2107974
Publikováno v:
Basic life sciences. 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::457155010e8748229b97993e8b51a822
https://pubmed.ncbi.nlm.nih.gov/3250531
https://pubmed.ncbi.nlm.nih.gov/3250531
Publikováno v:
Toxicology and applied pharmacology. 87(1)
Human peripheral blood mononuclear cells (PBMC) were isolated from healthy volunteers and exposed in vitro to phenytoin or carbamazepine, two widely used antiepileptic drugs (AED). This study investigated the effects of these drugs on natural killer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6781e67d3c606193dd844e9037ee93ce
https://pubmed.ncbi.nlm.nih.gov/3798446
https://pubmed.ncbi.nlm.nih.gov/3798446