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pro vyhledávání: '"R A, Comley"'
Autor:
R. Edward Comley, Matthew J. Dry
Publikováno v:
Experimental and Clinical Psychopharmacology. 28:112-129
Although the strength of the effect produced by alcohol is generally dose dependent, its effect on behavior cannot be reliably predicted by the dose alone because the dose effect has been shown to vary. Acute behavioral tolerance is a rapid decrease
Autor:
Matthew J. Dry, R. Edward Comley
Publikováno v:
Experimental and clinical psychopharmacology. 28(6)
Acute tolerance is a rapid decrease in the effect of alcohol relative to the blood alcohol concentration (BAC) occurring within the duration of a single dose of alcohol. It remains uncertain which cognitive domains are susceptible to acute tolerance,
Autor:
S, Ashworth, A, Berges, E A, Rabiner, A A, Wilson, R A, Comley, R Y K, Lai, R, Boardley, G, Searle, R N, Gunn, M, Laruelle, V J, Cunningham
Publikováno v:
British journal of pharmacology. 171(5)
This study aimed to investigate the relationship between the plasma concentration (PK) of the novel histamine H3 receptor antagonist, GSK239512, and the brain occupancy of H(3) receptors (RO) in healthy human volunteers.PET scans were obtained after
Autor:
R A Comley, J E Brignell
Publikováno v:
Journal of Physics E: Scientific Instruments. 14:963-967
The application of microprocessor instrumentation to a clinical EEG problem, detection of a waveform known to be associated with the epileptic fit, is examined. Reasons are advanced for the relative failure of earlier attempts to use the matched filt