Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R A, Borman"'
5-HT2B receptors play a key role in mediating the excitatory effects of 5-HT in human colon in vitro
Autor:
R. L. G. Sheldrick, R.A. Coleman, E.S. Ellis, Dan W. Harmer, J. Carey, Baxter Gordon Smith, N. Day, Nick Tilford, R. A. Borman
Publikováno v:
British Journal of Pharmacology. 135:1144-1151
5-Hydroxytryptamine (5-HT) is known to produce a number of different effects in the gastrointestinal tract of various species, and has been proposed to play a key role in a number of intestinal disorders in man, including irritable bowel syndrome (IB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a9f79dbe06bac3c24d94f28487e7bc
https://doi.org/10.1038/sj.bjp.0704571
https://doi.org/10.1038/sj.bjp.0704571
Publikováno v:
British Journal of Pharmacology. 123:231-236
We have investigated the effects of platelet-activating factor (PAF), an endogenous mediator of inflammation, on ion transport and prostaglandin synthesis in the human isolated colon. Application of PAF to the serosal surface of human colonic mucosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26142e6866869edb74091212479a565
https://doi.org/10.1038/sj.bjp.0701602
https://doi.org/10.1038/sj.bjp.0701602
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 23(8)
Prostaglandin E(2) (PGE(2) ) is an inflammatory mediator implicated in several gastrointestinal pathologies that affect normal intestinal transit. The aim was to establish the contribution of the four EP receptor types (EP(1-4) ), in human colon, tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23c6a341658033b0da95a1efdc3548d3
https://pubmed.ncbi.nlm.nih.gov/21605283
https://pubmed.ncbi.nlm.nih.gov/21605283
Autor:
G J, Sanger, S M, Westaway, A A, Barnes, D T, Macpherson, A I, Muir, E M, Jarvie, V N, Bolton, S, Cellek, E, Näslund, P M, Hellström, R A, Borman, W P, Unsworth, K L, Matthews, K, Lee
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 21(6)
There is an urgent clinical need for a safe, efficacious stimulant of gastric emptying; current therapies include erythromycin (an antibiotic with additional properties which preclude chronic use) and metoclopramide (a 5-hydroxytryptamine type 4 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::887cbe19e89bd93134b549f28be3ff3c
https://pubmed.ncbi.nlm.nih.gov/19374732
https://pubmed.ncbi.nlm.nih.gov/19374732
Autor:
A K, Bassil, R A, Borman, E M, Jarvie, R J, McArthur-Wilson, R, Thangiah, E Z H, Sung, K, Lee, G J, Sanger
Publikováno v:
British journal of pharmacology. 154(1)
Lubiprostone (Amitiza), a possible ClC-2 channel opener derived from prostaglandin E(1) and indicated for the treatment of constipation, increases chloride ion transport and fluid secretion into the intestinal lumen. As lubiprostone may also directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9667d9d29c75cb864a8a30d98281867
https://pubmed.ncbi.nlm.nih.gov/18332851
https://pubmed.ncbi.nlm.nih.gov/18332851
Autor:
R A, Borman, N S, Tilford, D W, Harmer, N, Day, E S, Ellis, R L G, Sheldrick, J, Carey, R A, Coleman, G S, Baxter
Publikováno v:
British journal of pharmacology. 135(5)
1. 5-Hydroxytryptamine (5-HT) is known to produce a number of different effects in the gastrointestinal tract of various species, and has been proposed to play a key role in a number of intestinal disorders in man, including irritable bowel syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed8f0e882a04d95b6e7dd3f2ab817537
https://pubmed.ncbi.nlm.nih.gov/11877320
https://pubmed.ncbi.nlm.nih.gov/11877320
Publikováno v:
Journal of Science and Medicine in Sport. 12:S58-S59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b89bcbb5dbe9ce2613e9865263914552
https://doi.org/10.1016/j.jsams.2008.12.137
https://doi.org/10.1016/j.jsams.2008.12.137
Autor:
D E, Burleigh, R A, Borman
Publikováno v:
Digestive diseases and sciences. 42(9)
Cholera toxin-induced intestinal secretion in intact rats requires a functioning myenteric plexus. The aim of this investigation was to determine whether neural elements were essential for cholera toxin to produce a secretory effect in human isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6130cf1f2f280fb5ff5ed4a6d56ff4cc
https://pubmed.ncbi.nlm.nih.gov/9331163
https://pubmed.ncbi.nlm.nih.gov/9331163
Publikováno v:
The Journal of foot surgery. 30(3)
The authors discuss treatment of the anticoagulated patient prior to elective surgery. They review factors that increase and decrease patient response to this therapy. Recommended procedure for dealing with the anticoagulated surgical patient is then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e67a5d847ca36cd5a014d780d64dba4
https://pubmed.ncbi.nlm.nih.gov/1875011
https://pubmed.ncbi.nlm.nih.gov/1875011
Autor:
J R, Feltes, R J, Borman
Publikováno v:
The Journal of foot surgery. 30(2)
Various medications are used by the lower extremity surgeon that affect the entire body. Nonsteroidal anti-inflammatory drugs are one such class. The authors review certain commonly used pharmaceuticals in this category, comparing the basic character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b95a15ef98de54a776ecf886b12c3278
https://pubmed.ncbi.nlm.nih.gov/1865075
https://pubmed.ncbi.nlm.nih.gov/1865075