Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R A, Bednar"'
Publikováno v:
Archives of Biochemistry and Biophysics. 308:240-253
A neutral proteolytic activity that converts human Big endothelin-1 (Big Et-1) to endothelin-1 has been identified from a human endothelial hybrid cell line, EAHY 926. This enzyme is an integral membrane protein and cofractionates with other enzymes
Autor:
Chin-Yi Jenny Hsu, Alfred P. Spada, Asher Zilberstein, R. A. Bednar, Alexander Levitzki, Persons Paul E
Publikováno v:
Journal of Biological Chemistry. 266:21105-21112
Lavendustin-A was reported to be a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor (Onoda, T., Iinuma, H., Sasaki, Y., Hamada, M., Isshibi, K., Naganawa, H., Takeuchi, T., Tatsuta, K., and Umezawa, K. (1989) J. Nat. Pro
Autor:
B, Bednar, J J, Cook, M A, Holahan, M E, Cunningham, P A, Jumes, R A, Bednar, G D, Hartman, R J, Gould
Publikováno v:
Blood. 94(2)
Most clinical trials with fibrinogen receptor antagonists (FRAs) have been associated with thrombocytopenia. This report describes the occurrence of thrombocytopenia in one chimpanzee and one rhesus monkey upon administration of potent FRAs. Chimpanz
Autor:
R A, Bednar, S L, Gaul, T G, Hamill, M S, Egbertson, J A, Shafer, G D, Hartman, R J, Gould, B, Bednar
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
A critical function of fibrinogen in hemostasis and thrombosis is to mediate platelet aggregation by binding selectively to an activated form of glycoprotein (GP) IIb/IIIa. Although numerous peptide and nonpeptide fibrinogen receptor antagonists have
Autor:
B, Bednar, M E, Cunningham, P A, McQueney, M S, Egbertson, B C, Askew, R A, Bednar, G D, Hartman, R J, Gould
Publikováno v:
Cytometry. 28(1)
Antagonists of platelet glycoprotein IIb/IIIa (GPIIb/IIIa) represent a new therapeutic approach in inhibiting platelet aggregation, thus providing a powerful form of antithrombotic therapy. The measurement of binding of arginine-glycine-aspartic acid
Publikováno v:
The Journal of biological chemistry. 266(31)
Lavendustin-A was reported to be a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor (Onoda, T., Iinuma, H., Sasaki, Y., Hamada, M., Isshibi, K., Naganawa, H., Takeuchi, T., Tatsuta, K., and Umezawa, K. (1989) J. Nat. Pro
Publikováno v:
Journal of Community Psychology. 5:246-256
Autor:
R F Colman, R A Bednar
Publikováno v:
Journal of Biological Chemistry. 257:11734-11739
DPN-dependent isocitrate dehydrogenase is composed of three distinct types of subunits: alpha, beta, and gamma which have molecular weights of about 40,000 but differ in isoelectric points. The relationship of subunit diversity to function was probed
Publikováno v:
American Journal of Orthopsychiatry. 44:497-502
The prevalence of behavior problems in an inner city elementary school was studied longitudinally. During the study period, the administrative size of the school was cut in half and the turnover of teachers decreased. There was a corresponding drop i
Autor:
J R Hadcock, R. A. Bednar
Publikováno v:
Journal of Biological Chemistry. 263:9582-9588
Chalcone isomerase from soybean has been purified 11,000-fold over the crude extract. The purification procedure features pseudo-affinity chromatography on an Amicon Matrex Orange A column with selective elution by a product of the enzymatic reaction