Zobrazeno 1 - 10
of 448
pro vyhledávání: '"R A, BRADY"'
Autor:
Daniel R. Schmidt, Iva Monique T. Gramatikov, Allison Sheen, Christopher L. Williams, Martina Hurwitz, Laura E. Dodge, Edward Holupka, W. S. Kiger, Milton R. Cornwall-Brady, Wei Huang, Howard H. Mak, Kathleen S Cormier, Charlene Condon, K. Dane Wittrup, Ömer H. Yilmaz, Mary Ann Stevenson, Julian D. Down, Scott R. Floyd, Jatin Roper, Matthew G. Vander Heiden
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-20 (2023)
Abstract Background Genetically engineered mouse models (GEMMs) of cancer are powerful tools to study mechanisms of disease progression and therapy response, yet little is known about how these models respond to multimodality therapy used in patients
Externí odkaz:
https://doaj.org/article/e2abc75b55aa4454ae9d147cefaedee3
Autor:
William M. Dawson, Kathryn L. Shelley, Jordan M. Fletcher, D. Arne Scott, Lucia Lombardi, Guto G. Rhys, Tania J. LaGambina, Ulrike Obst, Antony J. Burton, Jessica A. Cross, George Davies, Freddie J. O. Martin, Francis J. Wiseman, R. Leo Brady, David Tew, Christopher W. Wood, Derek N. Woolfson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Differential sensing aims to mimic senses such as taste and smell through the use of synthetic receptors. Here, the authors show that arrays of de novo designed peptide assemblies can be used as sensor components to distinguish various analytes and c
Externí odkaz:
https://doaj.org/article/a820f403adc549ffa2b3bf2e841354ca
Autor:
William M. Dawson, Eric J. M. Lang, Guto G. Rhys, Kathryn L. Shelley, Christopher Williams, R. Leo Brady, Matthew P. Crump, Adrian J. Mulholland, Derek N. Woolfson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
So far most of the de novo designed proteins are for single states only. Here, the authors present the de novo design and crystal structure determination of a coiled-coil peptide that assembles into multiple, distinct conformational states under the
Externí odkaz:
https://doaj.org/article/da6fbe49cbb74470820dc44739bd5079
Autor:
Sharmayne R. E. Brady, Donna M. Urquhart, Sultana Monira Hussain, Andrew Teichtahl, Yuanyuan Wang, Anita E. Wluka, Flavia Cicuttini
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Objectives Low back pain is the largest contributor to disability worldwide. The role of body composition as a risk factor for back pain remains unclear. Our aim was to examine the relationship between fat mass and fat distribution on back p
Externí odkaz:
https://doaj.org/article/4e95071004154c5089f4d240686557f8
Publikováno v:
Biogeosciences, Vol 16, Pp 329-346 (2019)
The air–sea CO2 fluxes in eastern boundary upwelling systems (EBUSs) vary strongly in time and space, with some of the highest flux densities globally. The processes controlling this variability have not yet been investigated consistently across al
Externí odkaz:
https://doaj.org/article/26a2468f02a24b839c99b74449152db5
Publikováno v:
Colorectal Disease. 25:747-756
Patients undergoing stoma surgery have a higher risk for early readmission. Some patients may benefit from closer postdischarge surveillance to provide early detection of complications and timely intervention. However, there is a paucity of validated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676570515fa3b3808248cf63f2cb0ac3
https://doi.org/10.1111/codi.16423
https://doi.org/10.1111/codi.16423
Autor:
Guto G. Rhys, Christopher W. Wood, Eric J. M. Lang, Adrian J. Mulholland, R. Leo Brady, Andrew R. Thomson, Derek N. Woolfson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Higher order coiled coils with five or more helices can form α-helical barrels. Here the authors show that placing β-branched aliphatic residues along the lumen yields stable and open α-helical barrels, which is of interest for the rational design
Externí odkaz:
https://doaj.org/article/5c02c52e40f94c5bb66b86f6007891f4
Autor:
Yuanyuan Wang, Catherine Lombard, Sultana Monira Hussain, Cheryce Harrison, Samantha Kozica, Sharmayne R. E. Brady, Helena Teede, Flavia M. Cicuttini
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Knee pain is common with obesity and weight gain being important risk factors. Previous clinical trials have focused on overweight or obese adults with knee pain and osteoarthritis and demonstrated modest effects of intense weight
Externí odkaz:
https://doaj.org/article/91ff3c97568a449899ee08c50c655ae4
Autor:
Matthew L. Brewer, David Dymock, R. Leo Brady, Bernhard B. Singer, Mumtaz Virji, Darryl J. Hill
Publikováno v:
Journal of Oral Microbiology, Vol 11, Iss 1 (2019)
Neisseria meningitidis, Haemophilus influenzae, and Moraxella catarrhalis are pathogenic bacteria adapted to reside on human respiratory mucosal epithelia. One common feature of these species is their ability to target members of the carcinoembryonic
Externí odkaz:
https://doaj.org/article/7f49ede41c7144dab76ae536caa2eb74
Autor:
Andrew Tassang, R. Michael Brady, Tosin Yinka Akintunde, George Enow Orock, Ewane Theophile Palle, Angwi Enow Tassang, Frederick Nchang Cho, Thierry Tassang, Walters Ndaka, Ncham Genesis Fointwen, Ngum Fru Paulette, Daniel Okono Ndongo
Publikováno v:
World Journal of Advanced Research and Reviews. 13:035-044
The ectocervix is the part of the uterus which plunges into the apex of the vagina. A stratified squamous epithelium covers it. The endocervical canal, which establishes communication between the vagina and the endometrial cavity, is paved with a muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be8bf9af44e6f4874af4219347d16ae
https://doi.org/10.30574/wjarr.2022.13.3.0183
https://doi.org/10.30574/wjarr.2022.13.3.0183