Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R A, Aldape"'
Autor:
M.E. Morales-Vallejo, R. Dondiego-Aldape, Joel Salazar-Flores, Rodrigo Rubi-Castellanos, Héctor Rangel-Villalobos, J.F. Muñoz-Valle, M. Anaya-Palafox, Ismael Nuño-Arana, R. Campos-Gutiérrez, N. Barojas-Pérez, Luis Miguel Canseco-Ávila, G. Flores-Flores
Publikováno v:
American Journal of Human Biology. 22:401-409
Mestizos currently represent most of the Mexican population (>90%); they are defined as individuals born in the country having a Spanish-derived last name, with family antecedents of Mexican ancestors back at least to the third generation. Mestizos a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffb5d23c6f1e051252f0a83e79f5cd6
https://doi.org/10.1002/ajhb.21013
https://doi.org/10.1002/ajhb.21013
Autor:
Shigeru Itoh, Mark A. Fleming, Frank J. Bruzzese, David J. Livingston, Matthew J. Fitzgibbon, John A. Thomson, Stephen P. Chambers, Patrick R. Connelly, R A Aldape, Manuel A. Navia
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1964-1968
Parallel measurements of the thermodynamics (free-energy, enthalpy, entropy and heat-capacity changes) of ligand binding to FK506 binding protein (FKBP-12) in H2O and D2O have been performed in an effort to probe the energetic contributions of single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d888ba7711d1d3d2cea5363a8cd4727
https://doi.org/10.1073/pnas.91.5.1964
https://doi.org/10.1073/pnas.91.5.1964
Publikováno v:
The Journal of biological chemistry. 270(32)
The 12- and 13-kDa FK506 binding proteins (FKBP12 and FKBP13) are cis-trans peptidyl-prolyl isomerases that bind the macrolides FK506 (Tacrolimus) and rapamycin (Sirolimus). The FKBP12.FK506 complex is immunosuppressive, acting as an inhibitor of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49d4c738363833b142df7fa0b92a391b
https://pubmed.ncbi.nlm.nih.gov/7642551
https://pubmed.ncbi.nlm.nih.gov/7642551
Autor:
K P, Wilson, J A, Black, J A, Thomson, E E, Kim, J P, Griffith, M A, Navia, M A, Murcko, S P, Chambers, R A, Aldape, S A, Raybuck
Publikováno v:
Nature. 370(6487)
Interleukin-1 beta converting enzyme (ICE) processes an inactive precursor to the proinflammatory cytokine, interleukin-1 beta, and may regulate programmed cell death in neuronal cells. The high-resolution structure of human ICE in complex with an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4abab6e10bf2176b03c74155162ac44e
https://pubmed.ncbi.nlm.nih.gov/8035871
https://pubmed.ncbi.nlm.nih.gov/8035871
Publikováno v:
The Journal of biological chemistry. 267(23)
The mechanism of FK506 immunosuppression has been proposed to proceed by formation of a tight-binding complex with the intracellular 12-kDa FK506-binding protein (FKBP12). The FK506-FKBP12 complex then acts as a specific high-affinity inhibitor of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60837e53cc9a46bef35fe2c0816aa601
https://pubmed.ncbi.nlm.nih.gov/1379588
https://pubmed.ncbi.nlm.nih.gov/1379588
Publikováno v:
The Journal of biological chemistry. 267(5)
FK506-binding protein (FKBP) catalyzes the cis-trans isomerization of the peptidyl-prolyl amide bond (the PPIase reaction) and is the major intracellular receptor for the immunosuppressive drugs FK506 and rapamycin. One mechanism proposed for catalys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::388509fdc73c5f5ec5937a02598c5b9d
https://pubmed.ncbi.nlm.nih.gov/1371117
https://pubmed.ncbi.nlm.nih.gov/1371117
Publikováno v:
Transplantation proceedings. 23(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3a6e88855ab5298975b7c4c18d4cb7b
https://pubmed.ncbi.nlm.nih.gov/1721299
https://pubmed.ncbi.nlm.nih.gov/1721299