Zobrazeno 1 - 8
of 8
pro vyhledávání: '"R A, Abagyan"'
Publikováno v:
Chemistry of Heterocyclic Compounds. 49:1500-1507
The condensation of 3-alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-keto esters or diethyl ethoxymethylenemalonate in the presence of acetic acid proceeds selectively to give 3-alkylamino-1-phenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones. The
Publikováno v:
ChemInform. 45
The condensation of 3-alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-keto esters or diethyl ethoxymethylenemalonate in the presence of acetic acid proceeds selectively to give 3-alkylamino-1-phenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones. The
Autor:
B V, Norledge, A M, Lambeir, R A, Abagyan, A, Rottmann, A M, Fernandez, V V, Filimonov, M G, Peter, R K, Wierenga
Publikováno v:
Proteins. 42(3)
Loop 8 (residues 232-242) in triosephosphate isomerase (TIM) is a highly conserved loop that forms a tight binding pocket for the phosphate moiety of the substrate. Its sequence includes the fully conserved, solvent-exposed Leu238. The tight phosphat
Publikováno v:
Journal of computer-aided molecular design. 14(6)
Binding of the Tat protein to TAR RNA is necessary for viral replication of HIV-1. We screened the Available Chemicals Directory (ACD) to identify ligands to bind to a TAR RNA structure using a four-step docking procedure: rigid docking first, follow
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(9)
A snake venom-like protease isolated by a differential display screen between normal and osteoarthritis (OA)-affected cartilage (designated as cSVP) has a cDNA sequence identical to TNF-alpha convertase enzyme (TACE). TACE shows the presence of an un
Publikováno v:
Biopolymers. 30(5-6)
Monte Carlo simulations [(N, V, T)-ensemble] were performed for the hydration shell of poly(dA-dT).poly(dA-dT) in canonical B form and for the hydration shell of poly(dA).poly(dT) in canonical B conformation and in a conformation with narrow minor gr
Autor:
R A, Abagyan
Publikováno v:
Biofizika. 28(3)
This study analyses all possible models of molecular packing of collagen in quasi-hexagonal lattice. Models which contain microfibril compressed to place molecular axes on quasi-hexagonal lattice are refused since in this case molecules occupy non-eq
Autor:
R A, Abagyan
Publikováno v:
Biofizika. 28(3)
Formula are obtained for the diffraction on fibrous biopolymers with strands alternating between segments of right- and left-handed helix. Additional set of reflections having definite positions and relative intensities is shown to be characteristic