Zobrazeno 1 - 10 of 294 pro vyhledávání: '"R A, Abagyan"'
1
Synthesis of [1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones by the Condensation of 3-Alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-Keto Esters or Diethyl Ethoxymethylenemalonate
Autor: Victor M. Chernyshev, Roman I. Zubatyuk, R. S. Abagyan, A. V. Astakhov
Publikováno v: Chemistry of Heterocyclic Compounds. 49:1500-1507
The condensation of 3-alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-keto esters or diethyl ethoxymethylenemalonate in the presence of acetic acid proceeds selectively to give 3-alkylamino-1-phenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0735c1aedbc89b3914fbd997025f21f
https://doi.org/10.1007/s10593-014-1401-y
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2
ChemInform Abstract: Synthesis of [1,2,4]Triazolo[4,3-a]pyrimidin-5(1H)-ones by the Condensation of 3-Alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-Keto Esters or Diethyl Ethoxymethylenemalonate
Autor: Roman I. Zubatyuk, Victor M. Chernyshev, A. V. Astakhov, R. S. Abagyan
Publikováno v: ChemInform. 45
The condensation of 3-alkylamino-5-amino-1-phenyl[1,2,4]triazoles with β-keto esters or diethyl ethoxymethylenemalonate in the presence of acetic acid proceeds selectively to give 3-alkylamino-1-phenyl[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd7e1bc263d8a59784a0ba6bc6627996
https://doi.org/10.1002/chin.201421182
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3
Modeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (loop 8) of triosephosphate isomerase: toward a new substrate specificity
Autor: B V, Norledge, A M, Lambeir, R A, Abagyan, A, Rottmann, A M, Fernandez, V V, Filimonov, M G, Peter, R K, Wierenga
Publikováno v: Proteins. 42(3)
Loop 8 (residues 232-242) in triosephosphate isomerase (TIM) is a highly conserved loop that forms a tight binding pocket for the phosphate moiety of the substrate. Its sequence includes the fully conserved, solvent-exposed Leu238. The tight phosphat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d750305b45f45f2026be11e74fafcc5
https://pubmed.ncbi.nlm.nih.gov/11151009
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4
Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR
Autor: A V, Filikov, V, Mohan, T A, Vickers, R H, Griffey, P D, Cook, R A, Abagyan, T L, James
Publikováno v: Journal of computer-aided molecular design. 14(6)
Binding of the Tat protein to TAR RNA is necessary for viral replication of HIV-1. We screened the Available Chemicals Directory (ACD) to identify ligands to bind to a TAR RNA structure using a four-step docking procedure: rigid docking first, follow
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fdb89e7b6ef6f86e5d79413c6fe6046
https://pubmed.ncbi.nlm.nih.gov/10921774
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5
TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha
Autor: I R, Patel, M G, Attur, R N, Patel, S A, Stuchin, R A, Abagyan, S B, Abramson, A R, Amin
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(9)
A snake venom-like protease isolated by a differential display screen between normal and osteoarthritis (OA)-affected cartilage (designated as cSVP) has a cDNA sequence identical to TNF-alpha convertase enzyme (TACE). TACE shows the presence of an un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69ebc6707ed23275868553dadaa0126c
https://pubmed.ncbi.nlm.nih.gov/9574564
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6
Akademický článek
Structural Relationships to Efficacy for Prazole‐Derived Antivirals.
Autor: Nyenhuis, David A.1 (AUTHOR), Watanabe, Susan2 (AUTHOR), Bernstein, Rebecca1 (AUTHOR), Swenson, Rolf E.3 (AUTHOR), Raju, Natarajan3 (AUTHOR), Sabbasani, Venkata R.3 (AUTHOR), Mushti, Chandrasekhar3 (AUTHOR), Lee, Duck‐Yeon4 (AUTHOR), Carter, Carol2 (AUTHOR) carol.carter@stonybrook.edu, Tjandra, Nico1 (AUTHOR) tjandran@nhlbi.nih.gov
Publikováno v: Advanced Science. May2024, Vol. 11 Issue 18, p1-13. 13p.
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7
Structure of the hydration shells of oligo(dA-dT).oligo(dA-dT) and oligo(dA).oligo(dT) tracts in B-type conformation on the basis of Monte Carlo calculations
Autor: F, Eisenhaber, V G, Tumanyan, R A, Abagyan
Publikováno v: Biopolymers. 30(5-6)
Monte Carlo simulations [(N, V, T)-ensemble] were performed for the hydration shell of poly(dA-dT).poly(dA-dT) in canonical B form and for the hydration shell of poly(dA).poly(dT) in canonical B conformation and in a conformation with narrow minor gr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::283ae772343b589d0442e44a805e1a51
https://pubmed.ncbi.nlm.nih.gov/2265229
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8
Akademický článek
Thermocatalytic Dehydrogenation‐Enabled Arene‐Alkane Couplings†.
Autor: Yu, Feng1,2, Tao, Renqing2, Gan, Lan2, Ni, Hao1,2, Kang, Qi‐Kai3, Liu, Guixia2 guixia@sioc.ac.cn, Huang, Zheng1,2,3 huangzh@sioc.ac.cn
Publikováno v: Chinese Journal of Chemistry. Aug2023, Vol. 41 Issue 16, p1905-1914. 10p.
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9
Akademický článek
Palladium-catalyzed cross-coupling of benzene sulfonhydrazides and benzyltrimethylammonium salts: Synthesis of diarylmethanes.
Autor: Yu, Weijie1 (AUTHOR), Wan, Juelin1 (AUTHOR), Chen, Puqing2 (AUTHOR), Zhao, Kuang1 (AUTHOR), Huang, Haijin3 (AUTHOR), Wang, Tao1 (AUTHOR), Luo, Jin2 (AUTHOR)
Publikováno v: Synthetic Communications. 2023, Vol. 53 Issue 6, p511-518. 8p. 4 Diagrams, 1 Chart.
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