Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rúben G. R. Pinheiro"'
Publikováno v:
Nanomaterials, Vol 11, Iss 10, p 2658 (2021)
Quercetin is a flavonol present in many vegetables and fruits. Generally, quercetin can be found in aglycone and glycoside forms, mainly in leaves. The absorption of this compound occurs in the large and small intestine, where it suffers glucuronidat
Externí odkaz:
https://doaj.org/article/1f6f46af4f65455599ba449e6faafe86
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11654, p 11654 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11654, p 11654 (2021)
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and possesses unique characteristics that make the delivery of drugs to the brain a great challenge. To achieve this purpose, it is necessary to design strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7660e50b950a7d0d242ca15ef87a64
https://doi.org/10.3390/ijms222111654
https://doi.org/10.3390/ijms222111654
Autor:
Rúben G. R. Pinheiro, Andreia Granja, Marina Pinheiro, Ana Rute Neves, Joana A. Loureiro, Salette Reis, Maria do Carmo Pereira
Publikováno v:
Pharmaceutical research. 37(7)
Purpose: Lipid nanoparticles (SLN and NLC) were functionalized with the RVG29 peptide in order to target the brain and increase the neuronal uptake through the nicotinic acetylcholine receptors. These nanosystems were loaded with quercetin to take ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be64a96dd97bede579df129d2d645ad4
https://pubmed.ncbi.nlm.nih.gov/32661727
https://pubmed.ncbi.nlm.nih.gov/32661727
Autor:
Maria do Carmo Pereira, Marina Pinheiro, Joana A. Loureiro, Rúben G. R. Pinheiro, Salette Reis, Ana Rute Neves, Andreia Granja
Publikováno v:
European Journal of Pharmaceutical Sciences. 148:105314
Quercetin was encapsulated in lipid nanoparticles (SLN and NLC) to take advantage of its neuroprotective properties in Alzheimer's disease. The nanoparticles were functionalized with transferrin to facilitate the passage across the blood-brain barrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71eb25f7c2c594ee2ba0e6592e79857
https://doi.org/10.1016/j.ejps.2020.105314
https://doi.org/10.1016/j.ejps.2020.105314
Publikováno v:
Nanoparticles in Life Sciences and Biomedicine
CIÊNCIAVITAE
CIÊNCIAVITAE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701daeab8e22a9f44e36fb0ca7fdb19a
https://doi.org/10.1201/9781351207355-9
https://doi.org/10.1201/9781351207355-9
Autor:
Ruben G. R. Pinheiro, Nuno L. Alves
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The microenvironments formed by cortical (c) and medullary (m) thymic epithelial cells (TECs) play a non-redundant role in the generation of functionally diverse and self-tolerant T cells. The role of TECs during the first weeks of the murine postnat
Externí odkaz:
https://doaj.org/article/953121fe0f19494db4b468f3a159081d