Indium-labelled human gut-derived T cells from healthy subjects with strong in vitro adhesion to MAdCAM-1 show no detectable homing to the gut in vivo

Autor: Kelsen, J, Agnholt, J, Falborg, L, Theil, Jørn, Rømer, J L, Hoffmann, Hans Jürgen, Dahlerup, J F

Publikováno v: Kelsen, J, Agnholt, J, Falborg, L, Nielsen, J T, Romer, J L, Hoffmann, H J & Dahlerup, J F 2004, ' Indium-labelled human gut-derived T cells from healthy subjects with strong in vitro adhesion to MAdCAM-1 show no detectable homing to the gut in vivo ' Clin. Exp. Immunol., vol. 138, no. 1, pp. 66-74 .
Kelsen, J, Agnholt, J, Falborg, L, Theil, J, Rømer, J L, Hoffmann, H J & Dahlerup, J F 2004, ' Indium-labelled human gut-derived T cells from healthy subjects with strong in vitro adhesion to MAdCAM-1 show no detectable homing to the gut in vivo ', Clinical and Experimental Immunology, vol. 138, no. 1, pp. 66-74 . https://doi.org/10.1111/j.1365-2249.2004.02578.x

Integrin alpha4beta 7 is the principal gut-homing receptor, and it is assumed that expression of this specific integrin directs lymphocytes to the gut in vivo. Adoptive cellular immunotherapy against inflammatory bowel disease (IBD) may depend on the

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https://pure.au.dk/portal/da/publications/indiumlabelled-human-gutderived-t-cells-from-healthy-subjects-with-strong-in-vitro-adhesion-to-madcam1-show-no-detectable-homing-to-the-gut-in-vivo(2634de20-efbc-11da-bee9-02004c4f4f50).html

FoxP3⁺CD4⁺CD25⁺ T cells with regulatory properties can be cultured from colonic mucosa of patients with Crohn's disease.

Autor: Kelsen, J., Agnholt, J., Hoffmann, H. J., Rømer, J. L., Hvas, C. L., Dahlerup, J. F.

Publikováno v: Clinical & Experimental Immunology; Sep2005, Vol. 141 Issue 3, p549-557, 9p

FoxP3(+)CD4(+)CD25(+) T cells with regulatory properties can be cultured from colonic mucosa of patients with Crohn's disease.

Autor: Kelsen J; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark. jekel@as.aaa.dk, Agnholt J, Hoffmann HJ, Rømer JL, Hvas CL, Dahlerup JF

Publikováno v: Clinical and experimental immunology [Clin Exp Immunol] 2005 Sep; Vol. 141 (3), pp. 549-57.