INSPIRED Symposium Part 4A: Access to CAR T Cell Therapy in Unique Populations with B Cell Acute Lymphoblastic Leukemia.

Autor: Winestone LE; Division of Allergy, Immunology, and BMT, Department of Pediatrics, UCSF Benioff Children's Hospitals, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California. Electronic address: lena.winestone@ucsf.edu., Bhojwani D; Division of Pediatric Hematology-Oncology, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center and Keck School of Medicine, University of Southern California, Los Angeles, California., Ghorashian S; Haematology Department, Great Ormond Street Hospital, London UK, Developmental Biology and Cancer, UCL-Great Ormond Street Institute of Child Health, University College London, London United Kingdom., Muffly L; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, California., Leahy AB; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Chao K; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California., Steineck A; MACC Fund Center for Cancer and Blood Disorders, Medical College of Wisconsin, Milwaukee, Wisconsin., Rössig C; University Children's Hospital Muenster, Pediatric Hematology and Oncology, Muenster, Germany; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Lamble A; Division of Hematology and Oncology, Seattle Children's Hospital, Department of Pediatrics, University of Washington, Seattle, Washington., Maude SL; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Myers R; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Rheingold SR; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Publikováno v: Transplantation and cellular therapy [Transplant Cell Ther] 2024 Jan; Vol. 30 (1), pp. 56-70. Date of Electronic Publication: 2023 Oct 10.

Antigen-specific redirection of off-the-shelf NK-92 cells using the universal CAR platform ‘‘UniCAR’’

Autor: Mitwasi, N., Feldmann, A., Arndt, C., Koristka, S., Loureiro, L. R., Berndt, N., Tonn, T., Bergmann, R., Rössig, C., Wels, W. S., Bachmann, M.

Publikováno v: International Conference on Lymphocyte Engineering, 31.03.-02.04.2022, Munich, Germany

Modifying of immune effector cells with chimeric antigen receptors (CARs) has revealed a promising therapeutic potential for targeting cancer, especially with CAR-modified T cells. However, the use of other immune cells like primary NK cells or NK ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::b5850174093bb2661da15bd0a4e11666
https://www.hzdr.de/publications/Publ-33879-1

Rapid diagnosis of an AT/RT by the detection of a heterozygous SMARCB1 germ line deletion in an infant

Autor: Kerl, K., Oyen, F., Giannikopoulou, D., Rössig, C., Rellensmann, G., Sandkötter, J., Brentrup, A., Selzer, G., Schneppenheim, R., Frühwald, Michael C.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3341::0166fe86c03e8b3eed3b0a5ddc6ac390
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72971

Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study.

Autor: Albert MH; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany., Sirait T; Statistical Unit and Data Office, European Society for Blood and Marrow Transplantation (EBMT), Leiden, The Netherlands., Eikema DJ; Statistical Unit and Data Office, European Society for Blood and Marrow Transplantation (EBMT), Leiden, The Netherlands., Bakunina K; Statistical Unit and Data Office, European Society for Blood and Marrow Transplantation (EBMT), Leiden, The Netherlands., Wehr C; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Suarez F; Department of Adult Hematology, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Fox ML; Department of Hematology, Hospital Universitari Vall d'Hebron, Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Hospital Campus, Barcelona, Spain., Mahlaoui N; Pediatric Immuno-Hematology and Rheumatology Unit, Necker-Enfants University Hospital and French National Reference Center for Primary Immunodeficiencies (CEREDIH), AP-HP, Paris, France., Gennery AR; Department of Pediatric Immunology & Haematopoietic Stem Cell Transplantation (HSCT), Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Lankester AC; Department of Pediatrics, Pediatric Stem Cell Transplantation Program, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands., Beier R; Department of Pediatric Hematology and Oncology, Medizinische Hochschule Hannover (MHH), Hannover, Germany., Bernardo ME; Department of Pediatric Immunohematology, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan, Italy., Bigley V; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Northern Center for Cancer Care, Newcastle upon Tyne Hospitals National Health Service (NHS) Foundation Trust, Newcastle upon Tyne, United Kingdom., Lindemans CA; Department of Pediatric Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatric Blood and Bone Marrow Transplantation, Princess Maxima Center, Utrecht, The Netherlands., Burns SO; Department of Immunology, Royal Free London Hospitals NHS Foundation Trust, London, United Kingdom.; Institute of Immunity and Transplantation, University College London (UCL), London, United Kingdom., Carpenter B; Department of Clinical Hematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom., Dybko J; Department of Hematology and Cellular Transplantation, Lower Silesian Center of Oncology, Wroclaw, Poland., Güngör T; Department of Hematology/Oncology/Immunology, Gene-Therapy, and Stem Cell Transplantation, University Children's Hospital Zurich - Eleonore Foundation & Children's Research Center (CRC), Zürich, Switzerland., Hauck F; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany., Lum SH; Department of Pediatric Immunology & Haematopoietic Stem Cell Transplantation (HSCT), Great North Children's Hospital, Newcastle upon Tyne, United Kingdom., Balashov D; Department of Hematopoietic Stem Cell Transplantation, Dmitriy Rogachev National Center for Pediatric Hematology, Oncology, and Immunology, Moscow, Russian Federation., Meisel R; Division of Pediatric Stem Cell Therapy, Department of Paediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany., Moshous D; Department of Pediatric Immunology, Hematology, and Rheumatology, Necker-Enfants Malades University Hospital, AP-HP, Paris, France., Schulz A; Department of Pediatrics, University Medical Center Ulm, Ulm, Germany., Speckmann C; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Pediatric Hematology and Oncology, Center for Pediatrics and Adolescent Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Slatter MA; Department of Pediatric Immunology & Haematopoietic Stem Cell Transplantation (HSCT), Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Strahm B; Department of Pediatric Hematology and Oncology, Center for Pediatrics and Adolescent Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Uckan-Cetinkaya D; Department of Pediatrics, Bone Marrow Transplantation (BMT) Unit, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Meyts I; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium.; Department of Microbiology, Immunology, and Transplantation, Katholieke Universiteit (KU) Leuven, Leuven, Belgium., Vallée TC; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany., Wynn R; Blood and Marrow Transplant Program, Royal Manchester Children's Hospital, Manchester, United Kingdom., Neven B; Department of Pediatric Immunology, Hematology, and Rheumatology, Necker-Enfants Malades University Hospital, AP-HP, Paris, France., Morris EC; Department of Immunology, Royal Free London Hospitals NHS Foundation Trust, London, United Kingdom.; Institute of Immunity and Transplantation, University College London (UCL), London, United Kingdom.; Department of Clinical Hematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom., Aiuti A, Maschan A, Aljurf M, Gedde-Dahl T, Gurman G, Bordon V, Kriván G, Locatelli F, Porta F, Valcárcel D, Beguin Y, Faraci M, Kröger N, Kulagin A, Shaw PJ, Veelken JH, Diaz de Heredia C, Fagioli F, Felber M, Gruhn B, Holter W, Rössig C, Sedlacek P, Apperley J, Ayas M, Bodova I, Choi G, Cornelissen JJ, Sirvent A, Khan A, Kupesiz A, Lenhoff S, Ozdogu H, von der Weid N, Rovira M, Schots R, Vinh DC

Publikováno v: Blood [Blood] 2022 Oct 06; Vol. 140 (14), pp. 1635-1649.

Inotuzumab ozogamicin as single agent in pediatric patients with relapsed and refractory acute lymphoblastic leukemia: results from a phase II trial.

Autor: Pennesi E; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands., Michels N; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Brivio E; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands., van der Velden VHJ; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Jiang Y; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Thano A; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Ammerlaan AJC; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands., Boer JM; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Beverloo HB; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Sleight B; Pfizer Inc, Groton, CT, USA., Chen Y; Pfizer Inc, Groton, CT, USA., Vormoor-Bürger B; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Rives S; Pediatric Oncology and Hematology Department, Hospital Sant Joan de Déu de Barcelona, Barcelona, Spain.; Institut de Recerca Sant Joan de Déu, Barcelona, Spain., Bielorai B; Division of Pediatric Hematology and Oncology, Sheba Medical Center, Ramat-Gan, Israel., Rössig C; Pediatric Hematology and Oncology, University Children's Hospital Muenster, Münster, Germany., Petit A; Department of pediatric Hematology and Oncology, Hopital Armand Trousseau, APHP, Sorbonne Université, Paris, France., Rizzari C; Pediatric Hematology-Oncology Unit, Department of Pediatrics, MBBM Foundation, ASST Monza, University of Milano-Bicocca, Monza, Italy., Engstler G; St Anna Children's Hospital, Medical University of Vienna, Vienna, Austria., Starý J; Department of Pediatric Hematology and Oncology, University Hospital Motol, Prague, Czech Republic., Bautista Sirvent FJ; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Department of Pediatric Oncology and Hematology, Hospital Niño Jesús, Madrid, Spain., Chen-Santel C; Department of Pediatrics, Division of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Pediatrics, Rostock University Medical Centre, Rostock, Germany., Bruno B; Pediatric Hematology, Hôpital Jeanne de Flandre, CHRU de Lille, Lille, France., Bertrand Y; Institute of Pediatric Hematology and Oncology, Civil Hospital of Lyon, Claude Bernard University, Lyon, France., Rialland F; Service Onco-Hématologie Pédiatrique, Hôpital Mère-Enfant, Nantes University Hospital, Nantes, France., Plat G; Service d'Hématologie-Immunologie-Oncologie, Hôpital des Enfants, CHU Toulouse, Toulouse, France., Reinhardt D; Department of Pediatric Oncology, Essen University Hospital, Essen, Germany., Vinti L; Department of Hematology, Oncology and of Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesú, Sapienza, University of Rome, Rome, Italy., Von Stackelberg A; Department of Pediatrics, Division of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; IntReALL study group, Berlin, Germany., Locatelli F; Department of Hematology, Oncology and of Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesú, Sapienza, University of Rome, Rome, Italy., Zwaan CM; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. c.m.zwaan@prinsesmaximacentrum.nl.; Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands. c.m.zwaan@prinsesmaximacentrum.nl.

Publikováno v: Leukemia [Leukemia] 2022 Jun; Vol. 36 (6), pp. 1516-1524. Date of Electronic Publication: 2022 Apr 25.