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pro vyhledávání: '"Röhn, G."'
Akademický článek
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Publikováno v:
68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); 20170514-20170517; Magdeburg; DOCMi.13.05 /20170609/
OBJECTIVE: MutT homolog1 (MTH1) is required for survival of cancer cells. These have irregular redox formations resulting in the production of reactive oxygen species which damage the deoxynucleoside triphosphate pool and subsequent the DNA. MTH1 pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493ab6f54ef9f493fdba4ec0c6176cb0
Publikováno v:
68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); 20170514-20170517; Magdeburg; DOCP 112 /20170609/
Objective: The ENPP (ectonucleotide pyrophosphatase/phosphodiesterase) ectoenzymes 1, 2 and 3 are type II transmembrane proteins with ATPase and ATP pyrophosphatase activities. ENPP3 (CD203c) is an activation marker for mast cells and basophils. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c431dd3671130edc9dc66f29d8364a
Autor:
Telentschak, S, Röhn, G, Görtz, L, von Spreckelsen, N, Stavrinou, P, Goldbrunner, R, Timmer, M
Publikováno v:
68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS); 20170514-20170517; Magdeburg; DOCDI.18.02 /20170609/
Objective: There is still no effective chemotherapy regimen for malignant meningiomas. Numerous studies on different malignancies indicate that Ran (Ras-related nuclear protein), some components of its pathway and TPX2 (Targeting protein for Xenopus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6a77c04621172f53c8abdbd1e5c8df
Publikováno v:
67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCMI.10.03 /20160608/
Objective: Adjuvant GBM chemotherapy is carried out with the alkylating agent Temozolomide (TMZ). The aggressiveness of GBM is mainly based on resistance to radio- and chemotherapy. In order to understand the underlying molecular mechanisms of resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56643e102caf3a61dc03c5b871dde967
Publikováno v:
66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20150607-20150610; Karlsruhe; DOCP 038 /20150602/
Objective: Cell surface molecules (CDs) are very important in diagnostics and a cornerstone in the process of understanding the behavior of tumors. A better understanding of the immunological surface of human glioma cells could lead to a deeper under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac7e79ce1b9931352e0c35eb0cf63fe
Publikováno v:
65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCP 044 /20140513/
Objective: Increasing knowledge of the molecular basis of gliomas supports the identification of tumor subgroups that differ in biological behaviour and response to treatment. IDH1 mutation, for example, seems to be crucial in distinguishing primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7186b5649ec15eac7e49d70a5bf2c7
Publikováno v:
65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCP 056 /20140513/
Objective: Real-time RT-PCR (RT-qPCR) is often used to analyse gene expression. In human meningiomas, many different reference genes are frequently used, however, no study has been performed yet to validate these “reference genes” with respect to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0443fb93b3602601dd868259f88c5d41
Publikováno v:
65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCP 054 /20140513/
Objective: The ribosomal protein L37a is a protein that is encoded by the RPL37A gene in humans. Ribosomes are organelles catalyzing protein synthesis. They consist of a large 60S- and a small 40S subunit. Together, these subunits are composed of 4 R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce38031c891fc8de1d560b292d120e65
Publikováno v:
64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20130526-20130529; Düsseldorf; DOCMO.11.05 /20130521/
Objective: The dioxin/aryl hydrocarbon receptor (AhR) is a transcription factor, to which a role in human cancerogenesis, cell cycle progression and transforming growth factor-β (TGF-β) has been attributed. The endogenous tumor-promoting ligand of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787166f42c6bc693a513e0e17105a0bd