Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Rómulo Aráoz"'
Autor:
Yves Bourne, Gerlind Sulzenbacher, Laurent Chabaud, Rómulo Aráoz, Zoran Radić, Sandrine Conrod, Palmer Taylor, Catherine Guillou, Jordi Molgó, Pascale Marchot
Publikováno v:
Marine Drugs, Vol 22, Iss 4, p 149 (2024)
Macrocyclic imine phycotoxins are an emerging class of chemical compounds associated with harmful algal blooms and shellfish toxicity. Earlier binding and electrophysiology experiments on nAChR subtypes and their soluble AChBP surrogates evidenced co
Externí odkaz:
https://doaj.org/article/e2a8c4f697904501875d503c589a25e4
Autor:
Evelyne Benoit, Aurélie Couesnon, Jiri Lindovsky, Bogdan I. Iorga, Rómulo Aráoz, Denis Servent, Armen Zakarian, Jordi Molgó
Publikováno v:
Marine Drugs, Vol 17, Iss 5, p 306 (2019)
Pinnatoxins (PnTXs) A-H constitute an emerging family belonging to the cyclic imine group of phycotoxins. Interest has been focused on these fast-acting and highly-potent toxins because they are widely found in contaminated shellfish. Despite their h
Externí odkaz:
https://doaj.org/article/309c1c6ae51141cc925bfe382303791f
Publikováno v:
Toxins, Vol 10, Iss 3, p 97 (2018)
Prorocentrolides are members of the cyclic imine phycotoxins family. Their chemical structure includes a 26-membered carbo-macrocycle and a 28-membered macrocyclic lactone arranged around a hexahydroisoquinoline that incorporates the characteristic c
Externí odkaz:
https://doaj.org/article/1a879bed43374ee3b339a454e17d3b5c
Autor:
Aurélie Couesnon, Rómulo Aráoz, Bogdan I. Iorga, Evelyne Benoit, Morgane Reynaud, Denis Servent, Jordi Molgó
Publikováno v:
Toxins, Vol 8, Iss 9, p 249 (2016)
The cyclic imine toxin 20-methyl spirolide G (20-meSPX-G), produced by the toxigenic dinoflagellate Alexandrium ostenfeldii/Alexandrium peruvianum, has been previously reported to contaminate shellfish in various European coastal locations, as reveal
Externí odkaz:
https://doaj.org/article/33f894b89f9042578f47da0b8495d3c4
Autor:
Antoine Huguet, Alfonso Lampen, Ludovic Le Hégarat, Valérie Fessard, Albert Braeuning, Jimmy Alarcan, Stefanie Hessel-Pras, Françoise Brée, Estelle Dubreil, Dominique Hurtaud-Pessel, Rómulo Aráoz, Belkacem Bouaita
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2019, 307, pp.17-25. ⟨10.1016/j.toxlet.2019.02.012⟩
Toxicology Letters, 2019, 307, pp.17-25. ⟨10.1016/j.toxlet.2019.02.012⟩
Toxicology Letters, Elsevier, 2019, 307, pp.17-25. ⟨10.1016/j.toxlet.2019.02.012⟩
Toxicology Letters, 2019, 307, pp.17-25. ⟨10.1016/j.toxlet.2019.02.012⟩
International audience; 13-Desmethylspirolide C (13-SPX-C) is a phycotoxin produced by dinoflagellates which can accumulate in shellfish. 13-SPX-C induces neurotoxic effects in rodents through blockade of nicotinic acetylcholine receptors. As no huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fe306e01358988ebb016cb07fc8a7c
https://hal-anses.archives-ouvertes.fr/anses-02083152/document
https://hal-anses.archives-ouvertes.fr/anses-02083152/document
Autor:
David Deniaud, Jean-Yves Le Questel, Sébastien G. Gouin, Rómulo Aráoz, Yoan Brissonnet, Sami Brument, Rui P. Sousa, Denis Servent, Jacques Lebreton, Lucie Percevault
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2019, 27 (5), pp.700-707. ⟨10.1016/j.bmc.2019.01.013⟩
Bioorganic and Medicinal Chemistry, 2019, 27 (5), pp.700-707. ⟨10.1016/j.bmc.2019.01.013⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2019, 27 (5), pp.700-707. ⟨10.1016/j.bmc.2019.01.013⟩
Bioorganic and Medicinal Chemistry, 2019, 27 (5), pp.700-707. ⟨10.1016/j.bmc.2019.01.013⟩
International audience; In the field of nicotinic acetylcholine receptors (nAChRs), recognized as important therapeutic targets, much effort has been dedicated to the development of nicotinic analogues to agonize or antagonize distinct homo-and heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44621ae622e05693fe1e93abc80f7db1
https://hal.archives-ouvertes.fr/hal-02140859/document
https://hal.archives-ouvertes.fr/hal-02140859/document
Publikováno v:
Toxicon
Toxicon, Elsevier, 2018, 149, pp.103-104. ⟨10.1016/j.toxicon.2018.02.029⟩
Toxicon, Elsevier, 2018, 149, pp.103-104. ⟨10.1016/j.toxicon.2018.02.029⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bd9ed23df41217305c9d69621a466b
https://hal.archives-ouvertes.fr/hal-03164771
https://hal.archives-ouvertes.fr/hal-03164771
Publikováno v:
Journal of Neurochemistry (2017) 142: 197-198
XVth International Symposium on Cholinergic Mechanisms
XVth International Symposium on Cholinergic Mechanisms, Oct 2017, Marseille, France. pp.197-198
HAL
XVth International Symposium on Cholinergic Mechanisms
XVth International Symposium on Cholinergic Mechanisms, Oct 2017, Marseille, France. pp.197-198
HAL
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8f663d06e42c3d4a3c9ac9c65ac81f94
https://hal.science/hal-02334372
https://hal.science/hal-02334372
Autor:
Denis Servent, Yves Bourne, Zoran Radić, Morgane Reynaud, Rómulo Aráoz, Gerlind Sulzenbacher, Jordi Molgó, Palmer Taylor, Pascale Marchot, Evelyne Benoit, Armen Zakarian
Publikováno v:
Structure (London, England : 1993)
Structure (London, England : 1993), 2015, 23 (6), pp.1106-15. ⟨10.1016/j.str.2015.04.009⟩
Structure (London, England : 1993), vol 23, iss 6
Structure (London, England : 1993), 2015, 23 (6), pp.1106-15. ⟨10.1016/j.str.2015.04.009⟩
Structure (London, England : 1993), vol 23, iss 6
International audience; Pinnatoxins are macrocyclic imine phycotoxins associated with algal blooms and shellfish toxicity. Functional analysis of pinnatoxin A and pinnatoxin G by binding and voltage-clamp electrophysiology on membrane-embedded neuron
Autor:
Julien Echterbille, Edwin De Pauw, Loïc Quinton, Rómulo Aráoz, N. Gilles, Gilles Mourier, Muriel Amar, Denis Servent
Publikováno v:
Toxicon
Toxicon, 2017, 130, pp.1-10. ⟨10.1016/j.toxicon.2017.02.023⟩
Toxicon, 2017, 130, pp.1-10. ⟨10.1016/j.toxicon.2017.02.023⟩
Animal toxins are peptides that often bind with remarkable affinity and selectivity to membrane receptors such as nicotinic acetylcholine receptors (nAChRs). The latter are, for example, targeted by α-conotoxins, a family of peptide toxins produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e3df2e97af7f090762f452f3457ccf
https://hal.science/hal-03633242
https://hal.science/hal-03633242