Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rócio I.R. Macias"'
Autor:
Corentin Louis, Tanguy Ferlier, Raffaële Leroux, Raphaël Pineau, Matthis Desoteux, Panagiotis Papoutsoglou, Delphine Leclerc, Gaëlle Angenard, Javier Vaquero, Rocio I.R. Macias, Julien Edeline, Cédric Coulouarn
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100900- (2023)
Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) is a deadly cancer worldwide with an increasing incidence and limited therapeutic options. Therefore, there is an urgent need to open the field to new concepts for identifying clinically relev
Externí odkaz:
https://doaj.org/article/d65272770452400784fb8235c71e509e
Autor:
Adelaida La Casta, Mariano Ponz-Sarvise, Chiara Braconi, Rócio I.R. Macias, Marco Marzioni, Alvaro Santos-Laso, Wacław Hołówko, Jouzas Kupčinskas, Angela Lamarca, Ana Landa-Magdalena, Juan W. Valle, Arndt Vogel, Raffaele Brustia, Vincenzo Cardinale, L. Fabris, Flora López-López, Trine Folseraas, Nigel B. Jamieson, Carpino Guido, Domenico Alvaro, Joris Erdmann, Jan Nm Ijzermans, Stefan Buettner, Anna Saborowski, Alejandro Forner, Laura Izquierdo-Sanchez, Gianpaolo Vidili, Marcin Krawczyk, Ana Lleo, Katja Evert, Viorel Scripcariu, Luis Bujanda, Jorge Adeva, Jan Philipp Jonas, Alexander Scheiter, Zeno Sparchez, Bas Groot Koerkamp, J. Andersen, Jesus M. Banales, Jose J.G. Marín, Kirsten Utpatel, Heinz-Josef Klümpen, Łukasz Krupa
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd6481d9063202291021f2501ffe866
https://doi.org/10.2139/ssrn.3844868
https://doi.org/10.2139/ssrn.3844868
Ascorbic acid (AA), the active form of vitamin C, is a potent antioxidant involved in many functions throughout the body, particularly in the liver. SLC2A and SLC23A plasma membrane transporters account for the efficient intestinal absorption and cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3eb48cb65051b618dcd5e92d65eb9e
https://doi.org/10.1016/b978-0-12-803951-9.00013-6
https://doi.org/10.1016/b978-0-12-803951-9.00013-6
Autor:
M.C. Garcia-Moreno, Rócio I.R. Macias, Julio J. Criado, Manuel Medarde, E. Rodrı́guez-Fernández, Jose J.G. Marin
Publikováno v:
BioMetals. 12:283-290
With a view to using bile acids as shuttles for delivering platinum-related cytostatic drugs to liver tumors, a chenodeoxycholylglycinato(CDCG)-derivative of platinum(II) has been synthesized. The complex - named Bamet-M2- was chemically characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312f0491299b05ba9054104c83f60d2a
https://doi.org/10.1023/a:1009289928944
https://doi.org/10.1023/a:1009289928944
Autor:
Monika Lewinska, PhD, Alvaro Santos-Laso, PhD, Enara Arretxe, PhD, Cristina Alonso, PhD, Ekaterina Zhuravleva, PhD, Raul Jimenez-Agüero, MD, PhD, Emma Eizaguirre, MD, PhD, María Jesús Pareja, MD, PhD, Manuel Romero-Gómez, MD, PhD, Marco Arrese Jimenez, MD, PhD, Malte P. Suppli, MD, PhD, Filip K. Knop, MD, PhD, Stine Karlsen Oversoe, MD, PhD, Gerda Elisabeth Villadsen, MD, PhD, Thomas Decaens, MD, PhD, Flair Jose Carrilho, MD, PhD, Claudia PMS de Oliveira, MD, PhD, Bruno Sangro, MD, PhD, Rocio I.R. Macias, MD, PhD, Jesus M. Banales, PhD, Jesper B. Andersen, PhD
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103661- (2021)
Background: Non-alcoholic fatty liver disease (NAFLD) is affecting more people globally. Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular carcinoma (NAFLD-HCC). This development can occur in a non-cirrhotic li
Externí odkaz:
https://doaj.org/article/a98663c5714b4b39a2da1a493b1539b3
Autor:
Ainhoa Lapitz, Ander Arbelaiz, Colm J. O’Rourke, Jose L. Lavin, Adelaida La Casta, Cesar Ibarra, Juan P. Jimeno, Alvaro Santos-Laso, Laura Izquierdo-Sanchez, Marcin Krawczyk, Maria J. Perugorria, Raul Jimenez-Aguero, Alberto Sanchez-Campos, Ioana Riaño, Esperanza Gónzalez, Frank Lammert, Marco Marzioni, Rocio I.R. Macias, Jose J. G. Marin, Tom H. Karlsen, Luis Bujanda, Juan M. Falcón-Pérez, Jesper B. Andersen, Ana M. Aransay, Pedro M. Rodrigues, Jesus M. Banales
Publikováno v:
Cells, Vol 9, Iss 3, p 721 (2020)
Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis of CCA is challenging and ac
Externí odkaz:
https://doaj.org/article/3b3b763b3a064cf0b5e939942071ce9a
Autor:
Jose J.G. Marin, Rocio I.R. Macias, Candela Cives-Losada, Ana Peleteiro-Vigil, Elisa Herraez, Elisa Lozano
Publikováno v:
Cells, Vol 9, Iss 2, p 498 (2020)
The dismal prognosis of patients with advanced cholangiocarcinoma (CCA) is due, in part, to the extreme resistance of this type of liver cancer to available chemotherapeutic agents. Among the complex mechanisms accounting for CCA chemoresistance are
Externí odkaz:
https://doaj.org/article/5939db0de36e49708baab083bd1bef2c
Publikováno v:
Journal of Functional Foods, Vol 5, Iss 3, Pp 1170-1179 (2013)
The present study investigated the antioxidant and cytoprotective effects of purified ethanolic extracts of Cytisus multiflorus, Lamium album L. and Thymus citriodorus plants. These extracts showed high antioxidant activity in DPPH and reducing power
Externí odkaz:
https://doaj.org/article/2a37667ddaa1458398a73999755311c8
Autor:
Susana Cuesta de Juan, Maria J. Monte, Rocio I.R. Macias, Valérie Wauthier, Pedro Buc Calderon, Jose J.G. Marin
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1362-1370 (2007)
Ontogenic changes in the rat bile acid (BA) pool, measured enzymatically and by GC-MS, and expression of enzymes (5α-reductase, 5β-reductase, and cytochrome P450 enzymes Cyp7a1, Cyp8b1, Cyp27 and Cyp3a11), transporters [bile salt export pump, sodiu
Externí odkaz:
https://doaj.org/article/f97c76c1a801447eb8b70a682d6e5643
Publikováno v:
Annals of Hepatology, Vol 4, Iss 2, Pp 70-76 (2005)
Since the excretion of potentially toxic cholephilic organic anions (COAs) produced by the fetus, such as bile acids and biliary pigments, cannot be performed by the fetal liver alone, the placenta and the maternal liver must play a key role collabor
Externí odkaz:
https://doaj.org/article/3c00e8cfb350498a81a7ecca34930997