Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Róbert Hromádka"'
Autor:
Oleksandra Vozniuk, Dr. Zdeněk Kejík, Kateřina Veselá, Markéta Skaličková, Petr Novotný, Róbert Hromádka, Dr. Jan Hajduch, Prof. Pavel Martásek, Prof. Milan Jakubek
Publikováno v:
ChemistryOpen, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract A simple, sensitive and quick HPLC method was developed for the determination of ketoprofen in cell culture media (EMEM, DMEM, RPMI). Separation was performed using a gradient on the C18 column with a mobile phase of acetonitrile and miliQ w
Externí odkaz:
https://doaj.org/article/0832fbd895a44ca19ceeff9b64fc0b8c
Autor:
Robert Kaplánek, Zdeněk Kejík, Jan Hajduch, Kateřina Veselá, Kateřina Kučnirová, Markéta Skaličková, Anna Venhauerová, Božena Hosnedlová, Róbert Hromádka, Petr Dytrych, Petr Novotný, Nikita Abramenko, Veronika Antonyová, David Hoskovec, Petr Babula, Michal Masařík, Pavel Martásek, Milan Jakubek
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115324- (2023)
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. Regulation of their activity by sp
Externí odkaz:
https://doaj.org/article/5c2fac8900f04ce2a9512f02c02393de
Autor:
Milan Jakubek, Zdeněk Kejík, Robert Kaplánek, Róbert Hromádka, Viera Šandriková, David Sýkora, Veronika Antonyová, Marian Urban, Petr Dytrych, Ivan Mikula, Pavel Martásek, Vladimír Král
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
Gastric cancer is a common oncological disease. Although enormous efforts have been expended, possible therapeutic modalities are still limited. For this reason, new therapeutic approaches and agents are highly requested and intensively developed. On
Externí odkaz:
https://doaj.org/article/9e4a3d568a3d47f3ba9619a08b68ebc9
Autor:
Martina Pajková, Róbert Hromádka, Lucie Mikšátková, Veronika Antonyová, Michal Masařík, Robert Kaplánek, Veronika Talianová, Zdeněk Kejík, Tereza Brogyányi, Pavel Martásek, David Sýkora, Milan Jakubek
Publikováno v:
DNA repair.
Neurodegenerative diseases (e.g. Alzheimer's and Parkinson's disease) are becoming increasingly problematic to healthcare systems. Therefore, their underlying mechanisms are trending topics of study in medicinal research. Numerous studies have eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203854d237c5f8c7d73935eee828f3ed
https://pubmed.ncbi.nlm.nih.gov/32502755
https://pubmed.ncbi.nlm.nih.gov/32502755
Autor:
Milan Jakubek, Róbert Hromádka, Vladimír Král, Pavel Martásek, Kateřina Vyhlídalová, Zdeněk Kejík, David Sýkora, Robert Kaplánek, Veronika Antonyová
Publikováno v:
Supramolecular Chemistry. 31:19-27
Benzoisothiazole-1,1-dioxide-based synthetic receptor was prepared by two step synthesis in 92 % overall yield. Its applicability for the determination of Zn(II) and interction with nucleic acids w...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74fb53928bcb219b1a8a34d162b277ca
https://doi.org/10.1080/10610278.2018.1523409
https://doi.org/10.1080/10610278.2018.1523409
Autor:
Zdeněk Kejík, Róbert Hromádka, Ivan Mikula, Viera Šandriková, Robert Kaplánek, Marian Urban, David Sýkora, Vladimír Král, Pavel Martásek, Petr Dytrych, Milan Jakubek, Veronika Antonyová
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss, Pp-(2019)
Gastric cancer is a common oncological disease. Although enormous efforts have been expended, possible therapeutic modalities are still limited. For this reason, new therapeutic approaches and agents are highly requested and intensively developed. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db65f0f4673e19eb87610de67a7737d7
http://www.sciencedirect.com/science/article/pii/S0753332219311795
http://www.sciencedirect.com/science/article/pii/S0753332219311795
Autor:
Jakub Hrib, A. Zak, Jakub Sirc, Róbert Hromádka, Jiri Michalek, Ondrej Slanar, Barbora Stankova, Eva Chylikova Krumbholcova, Radka Hobzova
Publikováno v:
Macromolecular Symposia. 366:14-22
Summary Hydrogels based on copolymers of N-vinylpyrrolidone and ethylidene-bis-3-(N-vinyl-2-pyrrolidone) (EBVP) were prepared as polymer matrices for controlled release of high loads of hydrophilic compounds into the gastrointestinal tract. EBVP was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc7eae1b4bfd2c2f1fd7e12c16fbdbb
https://doi.org/10.1002/masy.201650042
https://doi.org/10.1002/masy.201650042
Autor:
Robert Kaplánek, Zdeněk Kejík, Viera Šandriková, Róbert Hromádka, Milan Jakubek, Marian Urban, Vladimír Král, Pavel Martásek
Publikováno v:
Current medicinal chemistry. 26(20)
Filamentous ascomycetes (Neurospora and Monascus) have been studied for a long time because of their production of secondary metabolites such as microbial pigments. The ascomycetes represent an interesting group of compounds with high potential for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95028fc3c1e0bd40045dff08384c858
https://pubmed.ncbi.nlm.nih.gov/29600749
https://pubmed.ncbi.nlm.nih.gov/29600749
Autor:
Eva Tvrzická, Miroslav Zeman, Marek Vecka, Barbora Staňková, František Perlík, Róbert Hromádka, A. Žák
Publikováno v:
ResearcherID
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Niacin is considered to be a powerful drug for the treatment of lipid and lipoprotein abnormalities connected with "residual cardiovascular risk", which persist in high-risk patients even when the target goals of LDL-C are achieved with statin therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcedf53f6541164578085380f532c81
https://doi.org/10.12659/msm.893619
https://doi.org/10.12659/msm.893619
Publikováno v:
European journal of medicinal chemistry. 144
Polymeric bile acid sequestrants (BAS) have recently attracted much attention as lipid-lowering agents. These non-absorbable materials specifically bind bile acids (BAs) in the intestine, preventing bile acid (BA) reabsorption into the blood through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8baf48fd64bc2c50a5f09827e0e8b5d
https://pubmed.ncbi.nlm.nih.gov/29275230
https://pubmed.ncbi.nlm.nih.gov/29275230