Standardized pyrogen testing of medical products with the bacterial endotoxin test (BET) as a substitute for rabbit Pyrogen testing (RPT): A scoping review

Autor: José Mauro Granjeiro, Jesse Negherbon, Izabela Gimenes, Thomas Hartung, Janaína Spoladore, Gutemberg Gomes Alves, Róber Bachinski

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 74

The Bacterial Endotoxin Test (BET) is a method for exclusion of endotoxin-related pyrogen contamination in pharmaceutical products, as an alternative to the Rabbit Pyrogen Test (RPT). However, BET does not detect a broad range of biologically relevan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdb52cbda13f3620422a7cbac1359d3
https://pubmed.ncbi.nlm.nih.gov/33831473

Brazil starts to ban animal use in higher education: A positive and progressive development

Autor: Karynn Capilé, Gutemberg Gomes Alves, Luciano da Silva Alonso, Rita Leal Paixão, Vanessa Carli Bones, Rita de Cássia A. A. de Menezes, Monica L. Andersen, Débora Aita Gasparetto, Thales de Astrogildo e Tréz, Claudia M.C. Dias, Róber Bachinski, Valeska Regina Reque Ruiz, Júlia Maria Matera, Nick Jukes, Rita de Cassia Maria Garcia, Rosangela Ribeiro Gebara, Alexandro Aluísio Rocha, Simone Tostes de Oliveira, Mariângela Freitas de Almeida Souza

Publikováno v: Alternatives to laboratory animals : ATLA. 46(4)

The Brazilian government has published a resolution that bans animal use in some practical classes within undergraduate and high school technical education from April 2019. Resolution No. 38/2018, issued by the National Council for the Control of Ani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9692a29885c5c062cbb9f542dfa332a
https://pubmed.ncbi.nlm.nih.gov/30365336

Salivary protein polymorphisms and risk of dental caries: a systematic review

Autor: Erika Calvano Küchler, Róber Bachinski, Leonardo Santos Antunes, Diana Amado Baptista Dos Santos, Andrea Lips, Lívia Azeredo Alves Antunes, Gutemberg Gomes Alves, Andréa Vaz Braga Pintor

Publikováno v: Brazilian Oral Research, Volume: 31, Article number: e41, Published: 05 JUN 2017
Brazilian Oral Research, Vol 31, Iss 0 (2017)
Brazilian Oral Research v.31 2017
Brazilian Oral Research
Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO

Dental caries is an oral pathology associated with both lifestyle and genetic factors. The caries process can be influenced by salivary composition, which includes ions and proteins. Studies have described associations between salivary protein polymo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb5d6f777e9f178f3a3a692792216d2
https://doi.org/10.1590/1807-3107bor-2017.vol31.0041

2016 Lush Lobbying Prize Winner: 1R Institute of Promotion and Research for the Replacement of Animal Experimentation, Brazil

Autor: Róber Bachinski

Publikováno v: Alternatives to Laboratory Animals. 45:277-278

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dc17c4e668aa8529c1cbc2a86e15ac5
https://doi.org/10.1177/026119291704500502

A 3D Osteoblast In Vitro Model for the Evaluation of Biomedical Materials

Autor: Daniela Costa-Silva, Ana Carolina Batista, Adriana Linhares, Gutemberg Gomes Alves, Luciana Restle, Róber Bachinski, Emanuelle Stellet Lourenço

Publikováno v: Advances in Materials Science and Engineering, Vol 2015 (2015)

Biomedical materials for bone therapy are usually assessed for their biocompatibility and safety employing animal models orin vitromonolayer cell culture assays. However, alternativein vitromodels may offer controlled conditions closer to physiologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6dc045ab15437736018b59c5acc9a8
https://doaj.org/article/d0ea77b05335462e9264f791d6ab9118